4-(2-Dimethylaminoethyl)phenol
|
|
|
- CAS-Nr.
- 539-15-1
- Bezeichnung:
- 4-(2-Dimethylaminoethyl)phenol
- Englisch Name:
- Hordenine
- Synonyma:
- Hordenin;Hordeine;Anhalin;Cactine;Anhaline;Hordetin;Ordenina;Ordenine;Eremursin;Hordenine
- CBNumber:
- CB4747471
- Summenformel:
- C10H15NO
- Molgewicht:
- 165.23
- MOL-Datei:
- 539-15-1.mol
|
4-(2-Dimethylaminoethyl)phenol Eigenschaften
- Schmelzpunkt:
- 117-118°
- Siedepunkt:
- bp11 173°
- Dichte
- 1.0203 (rough estimate)
- Brechungsindex
- 1.4820 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- DMSO (Slightly), Methanol (Slightly)
- pka
- 10.05±0.26(Predicted)
- Farbe
- Pale Yellow to Dark Beige
- Merck
- 14,4746
- BRN
- 2207615
- LogP
- 1.400 (est)
- CAS Datenbank
- 539-15-1(CAS DataBase Reference)
- NIST chemische Informationen
- Phenol, 4-[2-(dimethylamino)ethyl]-(539-15-1)
Sicherheit
- Risiko- und Sicherheitserklärung
- Gefahreninformationscode (GHS)
| Kennzeichnung gefährlicher |
Xn |
|
|
| R-Sätze: |
22-36-43 |
|
|
| S-Sätze: |
26-36/37 |
|
|
| WGK Germany |
3 |
|
|
| HS Code |
29222990 |
|
|
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizität (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
|
|
| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P271 |
Nur im Freien oder in gut belüfteten Räumen verwenden. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P302+P352 |
BEI BERÜHRUNG MIT DER HAUT: Mit viel Wasser/... (Hersteller kann, falls zweckmäßig, ein Reinigungsmittel angeben oder, wenn Wasser eindeutig ungeeignet ist, ein alternatives Mittel empfehlen) waschen. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen. |
|
4-(2-Dimethylaminoethyl)phenol Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Hordenine (Item No. 21626) is a naturally occurring alkaloid found in a variety of plants, most commonly germinated barley (
Hordeum species) from which the name is derived, and is structurally classified as a phenethylamine. It is biosynthesized by the step-wise double methylation of tyramine . Hordenine binds to and activates the dopamine D
2 receptor (K
i = 13 μM) but antagonizes D
2 receptor β-arrestin recruitment. It inhibits tyrosinase activity and expression at concentrations ≥ 50 μM resulting in reduced melanin accumulation in human melanocytes. Hordenine is present in significant amounts in beer and can be measured in serum in the free form, for up to 2 hours, and the glucuronidated form, for up to 6 hours, after beer consumption. This product is intended for research and forensic applications.
Chemische Eigenschaften
Light yellow solid
Verwenden
Hordenine is suitable to study the effect of reed canary grass alkoloids on in vito digestibility. It is also suitable for use as a standard to identify endogenous hordenine in ungerminated and germinated barley by HPLC/diode array detection analysis. Hordenine may be used as an analytical reference material and in research on the activities of phenethylamine type alkaloids.
läuterung methode
Crystallise Hordenine from EtOH or H2O and sublime it at 105o/5mm. The 4,4’-dichlorodiphenyl disulfimide salt has m 145-146o (from Me2CO/H2O) [Runge et al. Chem Ber 88 50 1955]. [Beilstein 13 H 626, 13 I 236, 13 II 356, 13 III 1640, 13 IV 1790.]
4-(2-Dimethylaminoethyl)phenol Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
4-(2-Dimethylaminoethyl)phenol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global( 319)Lieferanten
539-15-1(4-(2-Dimethylaminoethyl)phenol)Verwandte Suche:
- AKOS 227-22
- Hordenine, froM D.tiliaefoliuM G.Don
- Anhalin
- Anhaline
- N,N-(DiMethyl-d6)tyraMine
- Ordenina-d6
- p-[2-[(DiMethyl-d6)aMino]ethyl]phenol
- Peyocactine-d6
- p-Hydroxy-N,N-(diMethyl-d6)phenethylaMine
- Anhaline
4-[2-(Dimethylamino)ethyl]phenol
4-Hydroxy-N,N-dimethylphenethylamine
- Hordenine SynonyMs 4-(2-DiMethylaMinoethyl)phenol
- Venlafaxine Impurity (4-(2-(Dimethylamino)ethyl)-Phenol)
- Hordenine
4-(2-Dimethylaminoethyl)phenol
- Eremursin
- Cactine
- Eremursine
- Hordetin
- N,N-Dimethyl-2-(4-hydroxyphenyl)ethylamine
- N,N-Dimethyl-4-hydroxy-beta-phenethylamine
- N,N-Dimethyl-p-hydroxyphenethylamine
- N,N-Dimethyltyramine
- Ordenina
- Ordenine
- p-[2-(Dimethylamino)ethyl]phenol
- Peyocactine
- Phenol, 4-[2-(dimethylamino)ethyl]-
- Phenol, p-[2-(dimethylamino)ethyl]-
- p-Hydroxy-N,N-dimethylphenethylamine
- p-[2-(dimethylamino)ethyl]phenol sulphate
- N,N-dimethyl-p-hydroxyphenylethyl
- HORDENINE(FREE BASE)(P)
- Dimethyl[2-(4-hydroxyphenyl)ethyl]amine
- Hordenine
- 4-(2-Dimethylaminoethyl)phenol
- N,N-DiMethyl-4-hydroxy-β-phenethylaMine
- 4-[2-(DiMethyl-d6)aMinoethyl]phenol
- Anhalin-d6
- Anhaline-d6
- Cactine-d6
- Hordenin-d6
- N,N-(DiMethyl-d6)-4-hydroxy-β-phenethylaMine
- N,N-(DiMethyl-d6)-p-hydroxyphenethylaMine
- Venlafaxine Impurity
- Hordenine, 98%, from D.tiliaefolium G.Don
- Desvenlafaxine Impurity 8
- Hordenine>
- 4-Hydroxy-N,N-dimethylphenethylamine
- Hordenine USP/EP/BP
- Hordenine (Ordenina
- TIANFU-CHEM CAS:539-15-1 Hordenine
- Hordenin
- Hordeine
- hordeniniumsulfat
- Barley malt alkali
- Hordenine (25 mg) (4-(2-(dimethylamino)ethyl)phenol)
- Hordenine, ≥ 98.0%
- 539-15-1
- HOC6H4CH22NCH32
