Talniflumate

Talniflumate Struktur
66898-62-2
CAS-Nr.
66898-62-2
Englisch Name:
Talniflumate
Synonyma:
somalgen;ba7602-06;TALNIFLUMATE;Talniflumate, >=99%;Talniflumate (BA 7602-06);TALNIFLUMATE(INTERMEDIATE);phthalidyl2-(3-trifluoromethylanilino)nicotinate;2-(α,α,α-Trifluoro-m-toluidino)nicotinic acid phthalidyl ester;phthalidyl2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinate;2-(alpha,alpha,alpha-trifluoro-m-toluidino)-nicotinicaciphthalidylester
CBNumber:
CB7315594
Summenformel:
C21H13F3N2O4
Molgewicht:
414.33
MOL-Datei:
66898-62-2.mol

Talniflumate Eigenschaften

Schmelzpunkt:
165-167°C
Siedepunkt:
534.6±50.0 °C(Predicted)
Dichte
1.49±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
Löslichkeit
Chlorform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka
2.72±0.10(Predicted)
Aggregatzustand
Solid
Farbe
Off-White to Pale Yellow
maximale Wellenlänge (λmax)
287nm(CHCl3)(lit.)
Merck 
14,9044
Stabilität:
Acid Sensitive, Moisture Sensitive

Sicherheit

RTECS-Nr. QT2999200
HS Code  2933.39.9200
Toxizität LD50 orally in rats: 12000 mg/kg (Los)

Talniflumate Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

White to pale yellow crystalline powder

Verwenden

Talniflumate is a nonaspirin and nonsteroidal anti-inflammatory drug.

Biologische Aktivität

Calcium-activated chloride channel (hCLCA1/mCLCA3) blocker; reduces mucin synthesis and release in cell culture and animal models. Possesses anti-inflammatory actions via inhibition of cyclooxygenases and inhibits Cl - /HCO 3 - exchanger activity. Increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome.

Talniflumate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Talniflumate Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 114)Lieferanten
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66898-62-2()Verwandte Suche:


  • 2-(alpha,alpha,alpha-trifluoro-m-toluidino)-nicotinicaciphthalidylester
  • 3-ftalidilicodelacido2-((3-(trifluormetil)fenil)amino)-3-piridincarboxilic
  • 3-phthalidylesterof2-((3-(trifluoromethyl)phenyl)amino)-3-pyridinecarboxyl
  • Talniflumate, >=99%
  • 2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinicacidphthalidylester
  • ba7602-06
  • phthalidyl2-(3-trifluoromethylanilino)nicotinate
  • phthalidyl2-(alpha,alpha,alpha-trifluoro-m-toluidino)nicotinate
  • somalgen
  • 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO]-3-PYRIDINECARBOXYLIC ACID 1,3-DIHYDRO-3-OXO-1-ISOBENZOFURANYL ESTER
  • 3-pyridinecarboxylic acid 2-{[(3-trifluoromethyl)phenyl]amino}-1,3-dihydro-3-oxo-1-soenzofuranyl ester
  • TALNIFLUMATE
  • TALNIFLUMATE(INTERMEDIATE)
  • 2-(α,α,α-Trifluoro-m-toluidino)nicotinic acid phthalidyl ester
  • 2-[[3-(Trifluoromethyl)phenyl]amino]nicotinic acid 1,3-dihydro-3-oxoisobenzofuran-1-yl ester
  • 2-[[3-(Trifluoromethyl)phenyl]amino]-1,3-dihydro-3-oxo-1-isobenzofuranyl3-pyridinecarboxylicacidester
  • 2-[3-(trifluoromethyl)anilino]-3-pyridinecarboxylic acid (3-oxo-1H-isobenzofuran-1-yl) ester
  • (3-oxo-1H-2-benzofuran-1-yl) 2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylate
  • 3-Pyridinecarboxylic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, 1,3-dihydro-3-oxo-1-isobenzofuranyl ester
  • Talniflumate (BA 7602-06)
  • 3-Oxo-1,3-dihydroisobenzofuran-1-yl 2-((3-(trifluoromethyl)phenyl)amino)nicotinate
  • 66898-62-2
  • 66898-62
  • C21H13F3N2O4
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