3,3',4',7-Tetrahydroxyflavon

Fisetin Struktur
528-48-3
CAS-Nr.
528-48-3
Bezeichnung:
3,3',4',7-Tetrahydroxyflavon
Englisch Name:
Fisetin
Synonyma:
Fisetine;Fisetin Powder;2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chroMen-4-one;fisetholz;superfustel;Fisetin Extract;5-desoxyquercetin;ungarischesgelbholz;Cotinus coggygria extract;viset
CBNumber:
CB8451569
Summenformel:
C15H10O6
Molgewicht:
286.24
MOL-Datei:
528-48-3.mol

3,3',4',7-Tetrahydroxyflavon Eigenschaften

Schmelzpunkt:
>330 °C(lit.)
Siedepunkt:
348.61°C (rough estimate)
Dichte
1.2981 (rough estimate)
Brechungsindex
1.4413 (estimate)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
Löslichkeit
DMSO (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
Colour Index 
75620
pka
6.83±0.40(Predicted)
Farbe
Pale Yellow to Very Dark Yellow
Merck 
14,4088
BRN 
292829
Stabilität:
Hygroscopic
InChI
InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
InChIKey
XHEFDIBZLJXQHF-UHFFFAOYSA-N
SMILES
C1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC=C2C(=O)C=1O
LogP
1.970 (est)
EPA chemische Informationen
Fisetin (528-48-3)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
R-Sätze: 36/37/38
S-Sätze: 22-24/25
WGK Germany  3
RTECS-Nr. LK9250000
10
TSCA  Yes
HS Code  29329990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P304+P340 BEI EINATMEN: Die Person an die frische Luft bringen und für ungehinderte Atmung sorgen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
P405 Unter Verschluss aufbewahren.

3,3',4',7-Tetrahydroxyflavon Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Beschreibung

Fisetin, a well-known plant flavonol from natural flavonoid group, is found in traditional medicines, plants, vegetables, fruits. Fisetin also has anti-oxidant, anti-inflammatory, anti-tumor effects[1].

Chemische Eigenschaften

OCHRE POWDER

Verwenden

Fisetin is used in biological studies as spleen tyrosine kinase inhibitors for autoimmune inflammation disease. This compound has neuroprotective properties.

Application

Fisetin is primarily used in laboratory bioactivity studies as an analytical standard for qualitative and quantitative analyses of Fisetin, and as a dietary supplement, and sells well for its potential anti-aging and cognitive enhancing effects. Because of its potent antioxidant and anti-inflammatory properties, it has been shown to have varying degrees of inhibitory effects on a wide range of diseases (e.g., cancer, Alzheimer's disease, anti-aging cells, and diabetes), and has been extensively studied in terms of its pharmacological effects in vitro and in vivo.

benefits

Fisetin is known to have antioxidant properties and demonstrates the specific biological activity of protecting functional macromolecules against stress, resulting in a benefit to cellular cytoprotection.It is also known to have anti-inflammatory, chemopreventive, and chemotherapeutic properties.

Allgemeine Beschreibung

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Anticancer Research

Fisetin is a plant polyphenol from the flavonoid group. It occurs in fruits and vegetablesincluding persimmons, strawberries, onions, cucumbers, and apples. It is anantioxidant, exerts anticarcinogenic effects in HCT-116 (human colon carcinoma)cells, and modulates protein kinase and lipid kinase pathways (Wang et al. 2012).Fisetin alter signaling pathway like MAPK, NF-κB, activators of transcription(JAK/STAT), Janus kinase/signal transducers, phosphoinositide-3-kinase-proteinkinase (PI3K/Akt), Wnt, and mammalian target of rapamycin (mTOR), therebyleading to cell cycle arrest in HL-60 cells (human acute promyelocytic leukemiacells) (Singh et al. 2016b). Thus, it exhibits inhibitory effects on adhesion, migration,invasion, and multidrug resistance (Suh et al. 2009).

Source

Fisetin is a plant flavonol from the flavonoid group of polyphenols. It can be found in many plants, where it serves as a yellow/ochre colouring agent. It is also found in many fruits and vegetables, such as strawberries, apples, persimmons, onions and cucumbers.

3,3',4',7-Tetrahydroxyflavon Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


3,3',4',7-Tetrahydroxyflavon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 415)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Bonerge(Hunan) Lifescience Co., Ltd.
+86-731-82791134 +86-18801900056
hank.h@bonerge.com China 30 58
Maintain Biotech Co., Ltd.
+86-75589664337 +86-15112661142
cami@maintain-bio.com China 66 58
Xi’an Sengmei Biotech Co.,Ltd.
+8615398038360
lionel@accenturebio.com China 288 58
XI AN SGONEK BIOLOGICAL TECHNOLOGY CO., LTD
15202951039
jason@sgonekbio.com China 268 58
ZhenYiBio Technology Inc
+8615309206328
alexxue@zhenyibio.com China 299 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578
sales@hbmojin.com China 12456 58
Hebei Lingding Biotechnology Co., Ltd.
+86-18031140164 +86-19933155420
erin@hbldbiotech.com China 878 58
Sinoway Industrial co., ltd.
0592-5800732; +8613806035118
xie@china-sinoway.com China 992 58
Wuhan Haorong Biotechnology Co.,ltd
+8618565342920
sales@chembj.net China 269 58
Hebei Jingbo New Material Technology Co., Ltd
+8619931165850
hbjbtech@163.com China 1000 58

528-48-3(3,3',4',7-Tetrahydroxyflavon)Verwandte Suche:


  • fustel
  • fustet
  • jungerfustik
  • superfustelk
  • 3,7,3',4'-TETRAHYDROXYFLAVONE
  • 5-DEOXYQUERCETIN
  • AKOS 244-37
  • NATURAL BROWN 1
  • Fisetin, tech., 70%
  • FISETIN hplc
  • fisidenolon
  • Flavone, 3,3',4',7-tetrahydroxy-
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-
  • Fustic Crystals
  • Fisetin, 70%, tech.
  • 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
  • Fisidenolon 1521
  • FISETIN WITH HPLC
  • 3,7-Dihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one
  • 5kg 10kg Purity:70%
  • Fisetin (Fustel)
  • boisbleudehonqrie
  • c.i.naturalbrown1
  • cotinin
  • fietin
  • ventinsumach
  • viset
  • youngfustic
  • youngfusticcrystals
  • ZanteFustic
  • Fisetin, froM Toxicodendron sylvestre
  • CI 75620
  • FISETIN
  • FISETIN HYDRATE
  • 3,2',4',7-TETRAHYDROXYFLAVONE
  • 3,3',4',7-TETRAHYDROXYFLAVONE
  • 3,3',4',7-TETRAHYDROXYFLAVONE HYDRATE
  • Fisetin,2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4h-1-benzopyran-4-on
  • 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-4h-1-benzopyran-4-on
  • 3,3’,4’,7-tetrahydroxy-flavon
  • Fisetin, 98%, from Toxicodendron sylvestre
  • Paint flavin
  • Lacquer yellow
  • Fisetin 50%-95%
  • Fisetin >
  • Fisetin USP/EP/BP
  • CCRIS-9034
  • NSC-407010)
  • Lacquercitrin 98%
  • 3,3'',4'',7-Tetrahydroxyflavone,97%
  • 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one
  • AI3 01132
  • AI301132
  • AI3-01132
  • fisetholz
  • superfustel
  • ungarischesgelbholz
  • Fisetine
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