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9-Phenylacridin

9-Phenylacridine Struktur
602-56-2
CAS-Nr.
602-56-2
Bezeichnung:
9-Phenylacridin
Englisch Name:
9-Phenylacridine
Synonyma:
9-PA;phenylacridine;9-phenyl-acridin;9-PHENYLACRIDINE;Acridine, 9-phenyl-;9-Phenylacridine>9-Phenylacridin (9-PA);3-propan-2-yloxy-1-cyclohex-2-enone;TIANFU-CHEM CAS:602-56-2 9-Phenylacridine
CBNumber:
CB9478127
Summenformel:
C19H13N
Molgewicht:
255.31
MOL-Datei:
602-56-2.mol
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9-Phenylacridin Eigenschaften

Schmelzpunkt:
184°C
Siedepunkt:
388.54°C (rough estimate)
Dichte
0.9418 (rough estimate)
Brechungsindex
1.6500 (estimate)
storage temp. 
Sealed in dry,Room Temperature
pka
5.45±0.10(Predicted)
Aggregatzustand
powder to crystal
Farbe
Light yellow to Amber to Dark green
InChI
InChI=1S/C19H13N/c1-2-8-14(9-3-1)19-15-10-4-6-12-17(15)20-18-13-7-5-11-16(18)19/h1-13H
InChIKey
MTRFEWTWIPAXLG-UHFFFAOYSA-N
SMILES
C1C2C(=NC3C(C=2C2=CC=CC=C2)=CC=CC=3)C=CC=1
CAS Datenbank
602-56-2(CAS DataBase Reference)
NIST chemische Informationen
Acridine, 9-phenyl-(602-56-2)
EPA chemische Informationen
Acridine, 9-phenyl- (602-56-2)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
S-Sätze: 22-24/25
HS Code  2933.99.8210
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

9-Phenylacridin Chemische Eigenschaften,Einsatz,Produktion Methoden

S-Sätze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

Research has found that 9-phenylacridine (ACPH) exhibited anticancer activity in cell lines and in vivo animal models. Bioinformatics studies have indicated that it could have topoisomerase I inhibitory activity. It could also act as a PARP 1 inhibitor and was very effective in combination with cisplatin in cell line-based assays. ACPH also satisfied all criteria for a candidate drug from the Lipinski rule and showed good cell uptake. ACPH alone was effective in the A375 melanoma cell line. ACPH could be used as a promising new photosensitizer[1-2]. 9-Phenylacridine is the parent base of chrysaniline or 3,6-diamino-9- phenylacridine, the chief constituent of the dyestuff phosphine. It is commonly used in the electronics industry as a free radical photoinitiator, significantly improving photo speed.

Beschreibung

9-Phenylacridine has antitumour activity. It can be used as a photosensitiser and can sensitise UVA-induced DNA damage in vitro and in cells. It also enhances cell killing by UVA. In addition. It is also used in photochemical research and as a raw material for organic synthesis.

9-Phenylacridin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Acridine, 1,2,3,4-tetrahydro-9-phenyl- 9-Phenyl-9,10-dihydroacridine Benzonitrile, 2-(phenylamino)- Methanone, phenyl[2-(phenylamino)phenyl]- TRIPHENYLMETHYLAMINE Diphenylammoniumchlorid DIPHENYLIODONIUM TRIFLUOROMETHANESULFONATE Acridin Benzolboronsäure 9-Chloracridin Diphenylzink Benzonitril Benzoesure Diphenylamin 2-Cyclohexen-1-on

Downstream Produkte

9-Phenylacridin Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 182)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Zhengzhou Lingzhiyue Technology Co., Ltd
+86-0371-55074660 +86-13783527580
 Lingzhiyue@aliyun.com China 3138 58
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177
 peter@yan-xi.com China 5993 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886
info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512
 info@tianfuchem.com China 21695 55
Tianjin Zhongxin Chemtech Co., Ltd. 		+86-022-66880623 +8618622897568
 sales@tjzxchem.com China 559 58
Zhengzhou Yuanli Biological Technology Co., Ltd 		0086-371-67897895
info@zzyuanli.cn CHINA 136 58
Tianjin Huiren Chemtech Co., Ltd 		86-22-23707858; +8613672008665
 huirentech@foxmail.com China 168 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873
 sales@chemdad.com China 39916 58
career henan chemical co 		+86-0371-86658258 15093356674;
 factory@coreychem.com China 29826 58
Antai Fine Chemical Technology Co.,Limited 		18503026267
 info@antaichem.com CHINA 9641 58

602-56-2(9-Phenylacridin)Verwandte Suche:

5,12-Dihydrochino[2,3-b]acridin-7,14-dion 9-Acridon N,N,N',N'-Tetramethylacridin-3,6-diaminmonohydrochlorid, Verbindung mit Zinkdichlorid Ethacridinlactat Amsacrine hydrochloride Ethacridin 9-(4-Aminophenyl)acridin-3-aminnitrat 9-Phenylacridin
  • 9-phenyl-acridin
  • phenylacridine
  • 9-PHENYLACRIDINE
  • Acridine, 9-phenyl-
  • 9-Phenylacridin (9-PA)
  • 3-propan-2-yloxy-1-cyclohex-2-enone
  • 9-PA
  • 9-Phenylacridine>
  • TIANFU-CHEM CAS:602-56-2 9-Phenylacridine
  • 602-56-2
  • C19H13N
  • Miscellaneous
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