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Benzonitril Produkt Beschreibung

Benzonitrile Struktur
100-47-0
CAS-Nr.
100-47-0
Bezeichnung:
Benzonitril
Englisch Name:
Benzonitrile
Synonyma:
BN;FB;3BN;BRR;BRN;2BNC;AKOS 91614;Benzoitrile;Benzontrile;Fenylkyanid
CBNumber:
CB7852585
Summenformel:
C7H5N
Molgewicht:
103.12
MOL-Datei:
100-47-0.mol

Benzonitril Eigenschaften

Schmelzpunkt:
-13 °C (lit.)
Siedepunkt:
191 °C (lit.)
Dichte
1.01
Dampfdichte
3.6 (vs air)
Dampfdruck
1 hPa at 20 °C
Brechungsindex
n20/D 1.528(lit.)
Flammpunkt:
161 °F
storage temp. 
Store below +30°C.
Löslichkeit
10g/l
Aggregatzustand
Liquid
Farbe
Clear colorless to slightly yellow
Relative polarity
0.333
Geruch (Odor)
Almond-like.
Explosionsgrenze
1.4-7.2%(V)
Wasserlöslichkeit
10 g/L (100 ºC)
maximale Wellenlänge (λmax)
λ: 300 nm Amax: 1.0
λ: 310 nm Amax: 0.40
λ: 335 nm Amax: 0.03
λ: 360-400 nm Amax: 0.01
Merck 
14,1097
BRN 
506893
Stabilität:
Stable. Incompatible with strong bases, strong acids, strong oxidizing agents, strong reducing agents. Air-sensitive. Combustible.
InChIKey
JFDZBHWFFUWGJE-UHFFFAOYSA-N
CAS Datenbank
100-47-0(CAS DataBase Reference)
NIST chemische Informationen
Benzonitrile(100-47-0)
EPA chemische Informationen
Benzonitrile (100-47-0)
Sicherheit
  • Risiko- und Sicherheitserklärung
  • Gefahreninformationscode (GHS)
Kennzeichnung gefährlicher Xn
R-Sätze: 21/22-38
S-Sätze: 23
RIDADR  UN 2224 6.1/PG 2
WGK Germany  2
RTECS-Nr. DI2450000
Selbstentzündungstemperatur 550 °C
TSCA  Yes
HazardClass  6.1
PackingGroup  II
HS Code  29269090
Giftige Stoffe Daten 100-47-0(Hazardous Substances Data)
Toxizität LDLo orl-rat: 720 mg/kg AMRL** TR-74-78,74
Bildanzeige (GHS)
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H227 Combustible liquid Flammable liquids Category 4 Warnung P210, P280, P370+P378, P403+P235,P501
H302 Gesundheitsschädlich bei Verschlucken. Akute Toxizität oral Kategorie 4 Warnung P264, P270, P301+P312, P330, P501
H312 Gesundheitsschädlich bei Hautkontakt. Akute Toxizität dermal Kategorie 4 Warnung P280,P302+P352, P312, P322, P363,P501
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung P264, P280, P305+P351+P338,P337+P313P
H331 Giftig bei Einatmen. Akute Toxizität inhalativ Kategorie 3 Achtung P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizität (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung
H371 Kann die Organe schädigen. Spezifische Zielorgan-Toxizität Kategorie 2 Warnung P260, P264, P270, P309+P311, P405,P501
H373 Kann die Organe schädigen bei längerer oder wiederholter Exposition. Spezifische Zielorgan-Toxizität (wiederholte Exposition) Kategorie 2 Warnung P260, P314, P501
H402 Harmful to aquatic life Hazardous to the aquatic environment, acute hazard Category 3
Sicherheit
P210 Von Hitze, heißen Oberflächen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen.
P260 Dampf/Aerosol/Nebel nicht einatmen.
P264 Nach Gebrauch gründlich waschen.
P264 Nach Gebrauch gründlich waschen.
P270 Bei Gebrauch nicht essen, trinken oder rauchen.
P271 Nur im Freien oder in gut belüfteten Räumen verwenden.
P273 Freisetzung in die Umwelt vermeiden.
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P321 Besondere Behandlung
P403+P235 An einem gut belüfteten Ort aufbewahren. Kühl halten.

Benzonitril Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD

FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.

CHEMISCHE GEFAHREN

Zersetzung beim Erhitzen oder Verbrennen unter Bildung giftiger Rauche mit Cyanwasserstoff und Stickstoffoxiden. Reagiert sehr heftig mit starken Säuren unter Bildunghochgiftigen Cyanwasserstoffs. Greift einige Kunststoffe an.

ARBEITSPLATZGRENZWERTE

TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).

AUFNAHMEWEGE

Aufnahme in den Körper durch Inhalation, über die Haut und durch Verschlucken.

INHALATIONSGEFAHREN

Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.

WIRKUNGEN BEI KURZZEITEXPOSITION

WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen, die Haut und die Atemwege. Möglich sind Auswirkungen auf die Zellatmung mit nachfolgender Zyanose. Die Auswirkungen treten u.U. verzögert ein. ärztliche Beobachtung notwendig.

LECKAGE

Ausgelaufene Flüssigkeit möglichst in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. NICHT in die Umwelt gelangen lassen. Chemikalienschutzanzug mit umgebungsluftunabhängigem Atemschutzgerät.

R-Sätze Betriebsanweisung:

R21/22:Gesundheitsschädlich bei Berührung mit der Haut und beim Verschlucken.

S-Sätze Betriebsanweisung:

S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).

Aussehen Eigenschaften

C7H5N; Benzoesäurenitril, Phenylcyanid; farblose, bittermandelartig riechende Flüssigkeit.

Allgemeine Beschreibung

Benzonitrile is a clear colorless liquid with an almond-like odor. Flash point 161°F. Denser (at 8.4 lb / gal) than water and slightly soluble in water. Used as a specialty solvent and to make other chemicals.

Gefahren für Mensch und Umwelt

Bei Verbrennung können cyanhaltige Gase entstehen.

Gesundheitsschädlich bei Berührung mit der Haut und beim Verschlucken.
Für Nitrile allgemein gilt: Höchste Vorsicht! Blausäurefreisetzung möglich - Blockade der Zellatmung, Herz-Kreislaufstörungen, Atemnot, Bewußtlosigkeit. Latenzzeit bis Wirkungseintritt.
Benzonitril ist wassergefährdend.

Schutzmaßnahmen und Verhaltensregeln

Im Abzug arbeiten.
Schutzhandschuhe (als kurzzeitiger Spritzschutz).

Verhalten im Gefahrfall

Mit flüssigkeitsbindendem Material (z.B. Rench-Rapid) aufnehmen. Ais Sondermüll entsorgen.
Kohlendioxid, Pulver
Im Brandfall können cyanhaltige Gase entstehen.

Erste Hilfe

Nach Hautkontakt: Betroffene Hautstellen gründlich mit Wasser und Seife abwaschen.
Nach Augenkontakt: Mindestens 15 Minuten unter fließendem Wasser bei geöffnetem Lidspalt spülen. Augenarzt konsultieren.
Nach Einatmen: Frischluft.
Nach Verschlucken: Viel Wasser trinken lassen; nur bei vollem Bewußtsein des Betroffenen Erbrechen auslösen. Bei Bewußtlosigkeit stabile Seitenlage. Arzt hinzuziehen.
Nach Kleidungskontakt: Kontaminierte Kleidung ausziehen.
Ersthelfer: siehe gesonderten Anschlag

Sachgerechte Entsorgung

Als Sondermüll entsorgen.

Chemische Eigenschaften

Bezonitrile is a colorless, oily liquid. It has an almond odor.

Chemische Eigenschaften

When heated to decomposition, benzonitrile emits toxic hydrogen cyanide and oxides of nitrogen (HSDB 1988).

Occurrence

Benzonitrile is reported to be found in natural cocoa aroma), in milk products, roasted filberts and peanuts and cooked trassi . Benzonitrile also has been detected in the thermal decomposition products of flexible polyurethane foam.

Verwenden

Manufacture of benzoguanamine; intermediate for rubber chemicals; solvent for nitrile rubber, spe- cialty lacquers, and many resins and polymers, and for many anhydrous metallic salts.

Verwenden

The most important commercial use for benzonitrile is the synthesis of benzoguanamine, which is a derivative of melamine and is used in protective coatings and molding resins.

Verwenden

Benzonitrile is a widely utilized as a solvent and an intermediate in industries making drugs, perfumes, dyes, rubber, textiles, resins and specialty lacquers. It finds application as a versatile precursor for many derivatives. It coordinates with transition metal to form complexes which act as synthetic intermediates.

Definition

ChEBI: A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a phenyl group.

Vorbereitung Methode

Benzonitrile can be produced in high yield by the vapor-phase catalytic ammoxidation of toluene.

Vorbereitung Methode

Benzonitrile can be prepared by one of the following methods: 1) on a small scale by the dehydration in an inert solvent with phosphorus oxychloride or benzenesulfonyl chloride and an organic amine; 2) from benzoic acid by heating with lead thiocyanate; 3) by heating sodium benzenesulfonate with sodium cyanide or by adding benzenediazonium chloride solution to a hot aq sodium cyanide solution containing cupric sulfate and distilling by ammoxidation of toluene.

Synthesis Reference(s)

Chemistry Letters, 13, p. 1913, 1984
Journal of the American Chemical Society, 111, p. 4903, 1989 DOI: 10.1021/ja00195a050
Tetrahedron Letters, 11, p. 2085, 1970

Air & Water Reaktionen

Slightly soluble in water.

Reaktivität anzeigen

The cyano group can be readily hydrolyzed in the presence of mineral acids to produce stable, moderately toxic benzoic acid . When heated to decomposition, Benzonitrile emits highly toxic fumes of nitrogen oxides and hydrogen cyanide [Sax, 9th ed., 1996, p. 353].

Hazard

High toxicity; absorbed by skin.

Health Hazard

Following an occupational accident in which a worker's head and clothing were drenched with benzonitrile (Zeller et al 1969), the worker suffered severe respiratory distress and tonic convulsions between periods of unconsciousness which lasted for 75 min. Thereafter he gradually recovered, but several years later he experienced episodes of unconsciousness which might have been related to the benzonitrile exposure.
Extensive reddening and blister formation resulted from accidental exposure of human skin to benzonitrile (Zeller et al 1969). A maximization test (Kligman 1966; Kligman and Epstein 1975) was also carried out on 35 volunteers. Benzonitrile was tested at a concentration of 2% in petrolatum on 27 volunteers in a mixed panel, and was found to produce no sensitization reactions after a 48 h closed-patch test (Opdyke 1979).

Health Hazard

Benzonitrile may enter the human body by ingestion, absorption through the skin, or inhalation. The earliest symptoms of cyano compound intoxication may be weakness, headaches, confusion, and occasionally nausea and vomiting. The respiratory rate and depth will usually be increased at the beginning and at later stages become slow and gasping. Blood pressure is usually normal, especially in the mild or moderately severe cases, although the pulse rate is usually more rapid than normal.

Brandgefahr

Special Hazards of Combustion Products: Toxic hydrogen cyanide and oxides of nitrogen may form in fire.

Chemische Reaktivität

Reactivity with Water No reaction; Reactivity with Common Materials: Will attack some plastics; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Industrielle Verwendung

Benzonitrile is used as an intermediate for rubber chemicals and as a solvent for nitrile rubber, specialty lacquers, many resins, polymers and for many anhydrous metallic salts (HSDB 1988; Hawley 1981). It is principally used as an intermediate for benzoguanamine (HSDB 1988). It is also used as an additive in nickel-plating baths, separating naphthalene and alkylnaphthalenes from non-aromatics by azetropic distillation; as jet-fuel additive; in cotton bleaching baths; as a drying additive for acrylic fibers; and in the removal of titanium tetrachloride and vanadium oxychloride from silicon tetrachloride (HSDB 1988; Smiley 1981). Benzonitrile is also used in perfumes at a maximum level of 0.2% in the final product (Opdyke 1979).

Sicherheitsprofil

Poison by intraperitoneal andsubcutaneous routes. Moderately toxic by ingestion,inhalation, and skin contact. A skinirritant. Combustible liquid. When heated todecomposition it emits toxic fumes of CN- and NOx.

mögliche Exposition

Bezonitrile is used as an electroplating agent; in organic synthesis of pharmaceuticals; dyestuffs; rubber chemicals; as a solvent and chemical intermediate.

Stoffwechsel

Benzonitrile is mainly hydroxylated in vivo to cyanophenols, a small amount being hydrolysed to benzoic acid (Williams 1959). Benzonitrile also forms 6>-hydroxybenzonitrile, m-hydroxybenzonitrile, and /p-hydroxybenzonitrile in rabbits (HSDB 1988). In rabbit, 50% of a dose of 150 mg/kg was converted to conjugated cyanophenols and 10% of the benzonitrile fed was excreted as benzoic acid. Hydrogen cyanide is not a metabolite of benzonitrile (Williams 1959) and cyanide was not found to be formed by benzonitrile either in vivo or in vitro (Tanii and Hashimoto 1984). The in vivo microsomal hydroxylation of specifically deuterated benzonitrile in the rat yielded mainly 4-hydroxybenzonitrile with 41% retention of deuterium (Daly et al 1968).

Versand/Shipping

UN2224 Benzonitrile, Hazard Class: 6.1; Labels: 6.1—Poisonous materials.

läuterung methode

Dry benzonitrile with CaSO4, CaCl2, MgSO4 or K2CO3, and distil it from P2O5 in an all-glass apparatus, under reduced pressure (b 69o/10mm), collecting the middle fraction. Distillation from CaH2 causes some decomposition of benzonitrile. Isonitriles can be removed by preliminary treatment with conc HCl until the odour of isonitrile (carbylamine) has gone, followed by preliminary drying with K2CO3. (This treatment also removes amines.) Steam distil (to remove small quantities of carbylamine). The distillate is extracted into ether, washed with dilute Na2CO3, dried overnight with CaCl2, and the ether is removed by evaporation. The residue is distilled at 40mm (b 96o) [Kice et al. J Am Chem Soc 82 834 1960]. Conductivity grade benzonitrile (specific conductance 2 x 10-8 mho) is obtained by treatment with anhydrous AlCl3, followed by rapid distillation at 40-50o under vacuum. After washing with alkali and drying with CaCl2, the distillate is redistilled in a vacuum several times at 35o before fractionally crystallising several times by partial freezing. It is dried over finely divided activated alumina from which it is withdrawn when required [Van Dyke & Harrison J Am Chem Soc 73 402 1951]. [Beilstein 9 IV 892.]

Inkompatibilitäten

May form explosive mixture with air. Strong acids which can release hydrogen cyanide. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Nitriles may polymerize in the presence of metals and some metal compounds. They are incompatible Benzonitrile 403 with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions. Nitriles are generally incompatible with other oxidizing agents such as peroxides and epoxides. The combination of bases and nitriles can produce hydrogen cyanide. Nitriles are hydrolyzed in both aqueous acid and base to give carboxylic acids (or salts of carboxylic acids). These reactions generate heat. Peroxides convert nitriles to amides. Nitriles can react vigorously with reducing agents. Acetonitrile and propionitrile are soluble in water, but nitriles higher than propionitrile have low aqueous solubility. They are also insoluble in aqueous acids.

Waste disposal

(1) Mix with calcium hypochlorite and flush to sewer with water or (2) incinerate.

Benzonitril Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Benzonitril Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 288)Lieferanten
Firmenname Telefon Fax E-Mail Land Produktkatalog Edge Rate
YANGZHOU SHUANGDING CHEM CO., LTD
18051432592 0514-83613866
0514-83423334 Alice@shuangdingchem.com CHINA 69 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 15426 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com China 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 9143 55
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679
86-0551-65418697 info@tnjchem.com China 3000 55
career henan chemical co
+86-0371-55982848
sales@coreychem.com China 29953 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5943 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58
Shandong chuangyingchemical Co., Ltd.
18853181302
sale@chuangyingchem.com CHINA 5917 58

100-47-0(Benzonitril)Verwandte Suche:


  • PHENYL CYANIDE
  • PHENYLMETHANITRILE
  • Benzontrile
  • Benzoitrile
  • BENZONITRILE, 99.9%, HPLC GRADE
  • BENZONITRILE, REAGENTPLUS, 99%
  • BENZONITRILE OEKANAL, 250 ML
  • BENZONITRILE, ANHYDROUS, 99+%
  • Benzonitrile, extra pure, 99%
  • Benzonitrile, for spectroscopy, 99+%
  • AKOS BBS-00004403
  • AKOS B004231
  • AKOS 91614
  • CYANOBENZENE
  • BENZONITRILE
  • BN
  • 2BNC
  • 3BN
  • Benzene, cyano-
  • benzenecarbonitrile
  • Benzenenitrile
  • Benzoic acid nitrile
  • benzoicacidnitrile
  • BRR
  • C.I.SulphurBlue7(53440)
  • cyano-benzen
  • FB
  • Fenylkyanid
  • ImmedialIndoneRF
  • KayakuSul-phurBlueBK
  • MifsuiSulphurBlueBC
  • ThionolBlue2BN
  • Benzonitrile ReagentPlus(R), 99%
  • Sulphur Blue BRN
  • Benzonitrile, 99+%
  • Benzonitrile, 99%, J&KSeal
  • Benzonitrile, 99%, SuperDry, water≤30 ppm, J&KSeal
  • benzonitride
  • Benzonitrile( 99%, HyDry, Water≤50 ppm (by K.F.))
  • Benzonitrile( 99%, HyDry, with molecular sieves, Water≤50 ppm (by K.F.))
  • Benzonitril
  • BRN
  • phenylcyanide,benzonitrile,cyanobenzene
  • BENZONITRILE,REAGENT
  • phenylnitrile
  • Benzonitrile, 99%, extra pure
  • Benzonitrile, for spectroscopy
  • Benzenenitrile (benzonitrile)
  • Benzonitrile,99+%,for spectroscopy
  • Benzonitrile,Phenyl cyanide
  • Benzonitrile 10g [100-47-0]
  • Benzonitrile, 99%, pure
  • Benzonitrile, extra pure, 99% 1LT
  • BENZONITRILE FOR SYNTHESIS
  • Benzonitrile, SuperDry, J&KSeal
  • Benzonitrile, J&KSeal
  • Benzonitrile, 99%, SpcDry, with Molecular sieves, Water≤50 ppM (by K.F.), SpcSeal
  • Benzonitrile 2
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