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Ly2835219

Ly2835219 structure

CAS No.: 1231930-82-7

Chemical Name:: Ly2835219

Synonyms: Bemaciclib;Abemaciclib Mesylate;CS-806;LY2835219;Bemaciclib(salt);LY2835219 mesylate;Bamaciclib Mesylate;LY2835219 USP/EP/BP;LY2835219/LY-2835219;ABEMACICLIB LY2835219 100MG

CBNumber:: CB00123200

Molecular Formula:: C28H36F2N8O3S

Molecular Weight:: 602.71

MDL Number:: MFCD25562906

MOL File:: 1231930-82-7.mol

MSDS File:: SDS

Last updated:2023-06-08 09:03:09

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Ly2835219 Properties

storage temp.	-20°
solubility	Soluble in DMSO (up to at least 25 mg/ml) or in Water (up to at least 25 mg/ml).
form	solid
color	Off-white
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
CAS DataBase Reference	1231930-82-7
FDA UNII	KKT462Q807

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501

NFPA 704

	0
2		0

Ly2835219 price More Price(21)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	17740	LY2835219 (methanesulfonate) ≥95%	1231930-82-7	1mg	$44	2024-03-01	Buy
Cayman Chemical	17740	LY2835219 (methanesulfonate) ≥95%	1231930-82-7	5mg	$63	2024-03-01	Buy
Cayman Chemical	17740	LY2835219 (methanesulfonate) ≥95%	1231930-82-7	10mg	$93	2024-03-01	Buy
TRC	E925710	N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamineMethanesulfonate	1231930-82-7	2.5mg	$185	2021-12-16	Buy
ChemScene	CS-1229	Abemaciclib(methanesulfonate) 99.95%	1231930-82-7	200mg	$190	2021-12-16	Buy

Product number	Packaging	Price	Buy
17740	1mg	$44	Buy
17740	5mg	$63	Buy
17740	10mg	$93	Buy
E925710	2.5mg	$185	Buy
CS-1229	200mg	$190	Buy

Ly2835219 Chemical Properties,Uses,Production

Description

Abemaciclib (LY2835219) is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively.

Mechanism of action

Through this mechanism, LY2835219 blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when used alone or in combination with other chemotherapeutic compounds.

Ly2835219 Preparation Products And Raw materials

Raw materials

Preparation Products

Ly2835219 Suppliers

Global( 182)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9342	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shenzhen Excellent Biotech Co., Ltd.	13480692018	ramyan@ex-biotech.com	CHINA	954	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Biochempartner	58
Hubei Jusheng Technology Co.,Ltd.	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Shenzhen Excellent Biotech Co., Ltd.	58
career henan chemical co	58

View Lastest Price from Ly2835219 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2021-10-08	Abemaciclib;LY2835219 1231929-97-7	US $585.00-0.00 / g	1g	98%+	100kgs	Wuhan Nutra Biotechnology Co.,Ltd
	2019-12-31	LY2835219 1231930-82-7	US $7.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

Abemaciclib;LY2835219
1231929-97-7
US $585.00-0.00 / g
98%+
Wuhan Nutra Biotechnology Co.,Ltd

LY2835219
1231930-82-7
US $7.00 / KG
99%
Career Henan Chemical Co

Abemaciclib mesylate (LY2835219) Spectrum

LY2835219(1231930-82-7)¹HNMR

1231930-82-7(Ly2835219)Related Search:

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2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine methanesulfonate (1:1) LY2835219 LY2835219 mesylate Bemaciclib(salt) N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine,methanesulfonic acid N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine methanesulfonate N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methyle LY2835219 Ms salt, Abemaciclib Ms salt Abemaciclib (methanesulfonate) Abemaciclib mesylate(LY2835219) LY2835219 (methanesulfonate) ABEMACICLIB (LY2835219);LY2835219;LY 2835219;LY-2835219 ABEMACICLIB LY2835219 100MG N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H LY2835219 LY2835219/LY-2835219 N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine Methanesulfonate N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine methanesulfonate (1:1) LY2835219methanesulfonic acid ABEMACICLIB METHANESULFONATE (LY2835219 METHANESULFONATE) LY2835219 (Abemaciclib) mesylate Abemaciclib mesylate(LY2835219 mesylate) CS-806 LY2835219; LY-2835219; LY 2835219 Bamaciclib Mesylate Abemaciclib (LY2835219) mesylate LY2835219 USP/EP/BP Abemaciclib Mesylate Bemaciclib N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzodimidazol-6-yl)pyrimidin-2-amine mesylate 1231930-82-7 C28H36F2N8O3S C27H32F2N8CH4O3S CH4O3SC27H32F2N8 Inhibitors