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MK-1775

MK-1775
MK-1775 structure
CAS No.
955365-80-7
Chemical Name:
MK-1775
Synonyms
MK-1775;MK-1175;AZD1775;Adavosertib);MK-1775,MK1775;MK-1775, >=98%;MK-1775, AZD1775,;MK-1775(955365-80-7);Adavosertib (MK-1775);MK-1775(AZD1775,Adavosertib)
CBNumber:
CB82514921
Molecular Formula:
C27H32N8O2
Formula Weight:
500.59538
MOL File:
955365-80-7.mol

MK-1775 Properties

Density 
1.292

SAFETY

MK-1775 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21266 MK-1775 ≥98% 955365-80-7 5mg $35 2018-11-19 Buy
Cayman Chemical 21266 MK-1775 ≥98% 955365-80-7 10mg $63 2018-11-19 Buy
Cayman Chemical 21266 MK-1775 ≥98% 955365-80-7 25mg $140 2018-11-19 Buy
Cayman Chemical 21266 MK-1775 ≥98% 955365-80-7 50mg $228 2018-11-19 Buy

MK-1775 Chemical Properties,Uses,Production

Description

MK-1775 is a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDK1, CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. MK-1775 is a type of biological therapy. It is a cancer growth blocker. It stops signals that cancer cells use to divide and grow. MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.

MK-1775 Preparation Products And Raw materials

Raw materials

Preparation Products


MK-1775 Suppliers

Global( 120)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21751 58
Chengdu Henghui Pharm Tec Co. Ltd.
13540674322 15828370308,QQ:2879822141
028-89481236 service@2hpharm.com CHINA 121 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20672 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24192 60
Biochempartner
0086-13720134139
candy@biochempartner.com CHINA 955 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 sales@guangaobio.com CHINA 23049 58
BOC Sciences
1-631-619-7922
1-631-614-7828 inquiry@bocsci.com United States 20115 58
Chengdu Henghui Pharmaceutical Co., Ltd.
86-028-89481236 13540674322 15828370308
86-028-89481236 service@2hpharm.com China 96 58
Artis Chemistry (Shanghai) Co. Ltd. 13918153394 0575-89298960
0575-89298961 sales@artis-standards.com China 1236 58

955365-80-7(MK-1775)Related Search:


  • 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-
  • Adavosertib)
  • 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
  • Adavosertib (MK-1775)
  • MK-1775(955365-80-7)
  • MK-1775(AZD1775,Adavosertib)
  • 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one
  • MK-1775
  • MK-1775,MK1775
  • 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1,2-dihydropyrazolo[3,4-d]pyrimidin-3-one
  • 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one MK 1775
  • MK 1775 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one
  • MK-1775, >=98%
  • MK-1175
  • 3H-Pyrazolo[3,4-d]pyrimidin-3-one, 1,2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-
  • MK-1775, AZD1775,
  • AZD1775
  • 955365-80-7
  • Other APIs
  • Inhibitors
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