ChemicalBook >> CAS DataBase List >>1H-Indole-3-carboxamide(9CI)

1H-Indole-3-carboxamide(9CI)

CAS No.
1670-85-5
Chemical Name:
1H-Indole-3-carboxamide(9CI)
Synonyms
1H-Indole-3-carboxamide(9CI);indole-3-yl carboxylic acid amide;2,6-Piperidinedione,3-[(6-chlorophenyl)methyl]-
CBNumber:
CB01282935
Molecular Formula:
C9H8N2O
Molecular Weight:
160.17
MDL Number:
MOL File:
1670-85-5.mol
MSDS File:
SDS
Last updated:2026-03-18 11:52:23
Product description Number Pack Size Price
1H-Indole-3-carboxylicAcidAmide I629028 100mg $65
1H-INDOLE-3-CARBOXYLIC ACID AMIDE 95.00% CHM0077922 1G $808.89
1H-INDOLE-3-CARBOXYLIC ACID AMIDE 95.00% CHM0077922 2.5G $1147.43
1H-INDOLE-3-CARBOXYLIC ACID AMIDE 95.00% CHM0077922 5G $1421.65
1H-Indole-3-carboxylicacidamide W3631 1g $192

1H-Indole-3-carboxamide(9CI) Properties

Melting point 201 °C
Boiling point 457.6±18.0 °C(Predicted)
Density 1.328±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 15.80±0.30(Predicted)
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
HS Code  2933998090

1H-Indole-3-carboxamide(9CI) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC I629028 1H-Indole-3-carboxylicAcidAmide 1670-85-5 100mg $65 2021-12-16 Buy
American Custom Chemicals Corporation CHM0077922 1H-INDOLE-3-CARBOXYLIC ACID AMIDE 95.00% 1670-85-5 1G $808.89 2021-12-16 Buy
American Custom Chemicals Corporation CHM0077922 1H-INDOLE-3-CARBOXYLIC ACID AMIDE 95.00% 1670-85-5 2.5G $1147.43 2021-12-16 Buy
American Custom Chemicals Corporation CHM0077922 1H-INDOLE-3-CARBOXYLIC ACID AMIDE 95.00% 1670-85-5 5G $1421.65 2021-12-16 Buy
AK Scientific W3631 1H-Indole-3-carboxylicacidamide 1670-85-5 1g $192 2021-12-16 Buy
Product number Packaging Price Buy
I629028 100mg $65 Buy
CHM0077922 1G $808.89 Buy
CHM0077922 2.5G $1147.43 Buy
CHM0077922 5G $1421.65 Buy
W3631 1g $192 Buy

1H-Indole-3-carboxamide(9CI) Chemical Properties,Uses,Production

Synthesis

3-Cyanoindole

5457-28-3

1H-Indole-3-carboxamide(9CI)

1670-85-5

GENERAL METHOD: To an anhydrous ethanol solution of 3-cyanoindole (15 mmol) was added 40% aqueous NaOH (5 mL) under stirring conditions. The reaction process was monitored by thin layer chromatography (TLC). Subsequently, 30% aqueous H2O2 solution (10.5 mL, 104.7 mmol) was slowly added dropwise to the reaction mixture. Upon completion of the reaction, the precipitated solid was collected by filtration, washed with water and recrystallized with anhydrous ethanol. Finally, the product was dried under vacuum to give 1H-indole-3-carboxamide (20a). The product was a white solid in 75% yield with a melting point of 195-197 °C (literature value 197-199 °C [31]).1H NMR (δ, ppm): 6.84 (s, 1H, NH), 7.13-7.21 (m, 2H, ArH), 7.47 (d, J = 8.0 Hz, 2H, ArH), 8.08 (s, 1H, NH), 8.20 (d, J = 7.5 Hz, 1H, ArH), 11.60 (s, 1H, NH).

References

[1] Applied Organometallic Chemistry, 2014, vol. 28, # 12, p. 900 - 907
[2] Catalysis Science and Technology, 2015, vol. 5, # 3, p. 1606 - 1622
[3] Synthetic Communications, 2013, vol. 43, # 21, p. 2867 - 2875
[4] Dalton Transactions, 2016, vol. 45, # 34, p. 13590 - 13603
[5] Russian Journal of General Chemistry, 2017, vol. 87, # 12, p. 3006 - 3016

1H-Indole-3-carboxamide(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole-3-carboxamide(9CI) Suppliers

Global( 39)Suppliers
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1H-Indole-3-carboxamide(9CI) Spectrum

1H-Indole-3-carboxamide(9CI) indole-3-yl carboxylic acid amide 2,6-Piperidinedione,3-[(6-chlorophenyl)methyl]- 1670-85-5 AMIDE