9-keto Fluprostenol isopropyl ester
- CAS No.
- 1219032-18-4
- Chemical Name:
- 9-keto Fluprostenol isopropyl ester
- Synonyms
- Travoprost 12;9-Keto Travoprost;Travoprost Impurity 21;Travoprost Impurity 35;9-KETO FLUPROSTENOL ISOPROPYL ESTER;FLUPROSTENOL PROSTAGLANDIN E2 ISOPROPYL ESTER;Travoprost Impurity 16（9-keto Fluprostenol Isopropyl Ester）;(+)-9-OXO-11ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC-ACID, ISOPROPYL ESTER;(+)-9-OXO-11ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC-ACID, ISOPROPYL ESTER;5-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-5-oxocyclopentyl]-, 1-methylethyl ester, (5Z)-
- CBNumber:
- CB1143711
- Molecular Formula:
- C26H33F3O6
- Molecular Weight:
- 498.53
- MDL Number:
- MFCD02259341
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H225-H319 | |||||||||
| Precautionary statements | P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501 | |||||||||
| NFPA 704 |
|
9-keto Fluprostenol isopropyl ester price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16782 | 9-keto Fluprostenol isopropyl ester ≥98% | 1219032-18-4 | 1mg | $88 | 2024-03-01 | Buy |
| Cayman Chemical | 16782 | 9-keto Fluprostenol isopropyl ester ≥98% | 1219032-18-4 | 5mg | $389 | 2024-03-01 | Buy |
| Cayman Chemical | 16782 | 9-keto Fluprostenol isopropyl ester ≥98% | 1219032-18-4 | 10mg | $691 | 2024-03-01 | Buy |
| AK Scientific | 1006AH | (+)-9-oxo-11alpha,15R-Dihydroxy-16-(3-(trifluoromethyl)Phenoxy)-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-oicacidisopropylester | 1219032-18-4 | 10mg | $866 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | MTB0002293 | (+)-9-OXO-11ALPHA,15R-DIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID ISOPROPYL ESTER 95.00% | 1219032-18-4 | 5MG | $502.76 | 2021-12-16 | Buy |
9-keto Fluprostenol isopropyl ester Chemical Properties,Uses,Production
Uses
9-Keto Travoprost is an impurity of Travoprost (T715600), a selective FP prostaglandin receptor agonist used to treat glaucoma (1,2).
Uses
Fluprostenol is a well-studied, potent analog of prostaglandin F2α (PGF2α) and acts primarily through the FP receptor. 9-keto Fluprostenol is an analog of PGE2 with structural modifications intended to give it a prolonged half-life and greater potency. 9-keto Fluprostenol isopropyl ester has the potential to act as an EP agonist in prodrug form. However, no studies on the pharmacology of this compound have been published to date. In addition 9-keto fluprostenol isopropyl ester is a potential metabolite of Travoprost, which is the Alcon trade name for fluprostenol isopropyl ester. In monkey cornea, this transformation was observed as a product of NADP+-dependent 15-hydroxyprostaglandin dehydrogenase when the closely related analog Latanoprost was used as a substrate. Certain F-series prostaglandins have been shown to be converted to the corresponding E-series compounds in rabbit liver and human platelet preparations.
9-keto Fluprostenol isopropyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17994 | 56 |
| Hubei Yangxin Medical Technology Co., Ltd. | 15374522761 | 3003392093@qq.com | China | 7934 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 | synstar518@163.com | China | 1991 | 58 |
| TOSUN PHARM | 020-61855200 13326451905 | 2881290884@qq.com | China | 7497 | 58 |
| Guangzhou Dreampharm Biotechnology Co., Ltd. | 17825480238 | 3008233717@qq.com | China | 9843 | 12 |
| Jinan blalong chemical co. LTD | 2710913286@.com | 1513643261@qq.com | China | 14253 | 58 |
| Taizhou Nanfeng Pharmaceutical Research Institute | 12345678910 | nanfengdrug@163.com | China | 15323 | 58 |