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(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine structure

CAS No.: 327623-37-0

Chemical Name:: (2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

Synonyms: Aprepitant Impurity 1;Aprepitant Impurity 11;Fosaprepitant Impurity 30;Aprepitant M2 Metabolite Enantiomer;Aprepitant Impurity 1 Hydrochloride;Aprepitant Impurity 10 Hydrochloride;Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer;Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1’Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant;(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine

CBNumber:: CB12657010

Molecular Formula:: C20H18F7NO2

Molecular Weight:: 437.35

MDL Number:: MFCD25976444

MOL File:: 327623-37-0.mol

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(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Properties

Boiling point	387.9±42.0 °C(Predicted)
Density	1.37±0.1 g/cm3(Predicted)
pka	6.93±0.60(Predicted)

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	D297830	Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1''S)-Aprepitant	327623-37-0	1mg	$90	2021-12-16	Buy

Product number	Packaging	Price	Buy
D297830	1mg	$90	Buy

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Chemical Properties,Uses,Production

Uses

Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1''S)-Aprepitant is an impurity of Aprepitant (A729800); a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine Suppliers

Global( 41)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14336	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
S.Z. PhyStandard Bio-Tech. Co., Ltd.	0755-4000505016 13380397412	3001272453@qq.com	China	4991	50
CEG Chemical Science&Technology Co., Ltd.	Mobile:13665161512		China	1785	58
GIHI CHEMICALS CO.,LTD	0086-571-86217390	Sales@gihichem.com	China	861	58
Shanghai Ranxon Chemical Co., Ltd.	13148101715	2073632910@qq.com	China	38	55
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Shanghai HuanChuan Industry Co.,Ltd.	021-61478794	sales@hcshhai.com	China	9798	50

Supplier	Advantage
Hubei Jusheng Technology Co.,Ltd.	58
Standardpharm Co. Ltd.	58
China National Standard Pharmaceutical Corporation Limited	58
BOC Sciences	65
S.Z. PhyStandard Bio-Tech. Co., Ltd.	50
CEG Chemical Science&Technology Co., Ltd.	58
GIHI CHEMICALS CO.,LTD	58
Shanghai Ranxon Chemical Co., Ltd.	55
Shanghai Kewel Chemical Co., Ltd.	50
Shanghai HuanChuan Industry Co.,Ltd.	50

327623-37-0((2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine)Related Search:

(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(phenyl)Morpholine Aprepitant Fosaprepitant dimeglumine Aprepitant Aprepitant

Aprepitant Fosaprepitant Impurity 6 (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanol

4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE Aprepitant Fosaprepitant Impurity 5 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one

1,1,1-Trimethoxy-2-chloroethane Aprepitant Benzyl dihydrogen phosphate

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(2S,3R)-2-((S)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine (2S,3R)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride (2S,3R)-2-[(1S)-1-(3,5-bis-trifluoro-Methylphenyl)ethoxy]-3-(4-fluorophenyl)Morpholine Aprepitant Impurity 1 Des-1,2,4-triazol-3-one-5-methyl (2S,3R,1'S)-Aprepitant Aprepitant Impurity 11 Aprepitant M2 Metabolite (1S, 2S, 3R)-Isomer Fosaprepitant Impurity 30 Aprepitant Impurity 1 Hydrochloride Aprepitant M2 Metabolite Enantiomer Morpholine, 2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2S,3R)- Des-1,2,4-triazol-3-one-5-methyl(2S,3R,1&rsquo Aprepitant Impurity 10 Hydrochloride 327623-37-0