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2-CHLOROQUINOLINE-3-CARBALDEHYDE

2-CHLOROQUINOLINE-3-CARBALDEHYDE structure

CAS No.: 73568-25-9

Chemical Name:: 2-CHLOROQUINOLINE-3-CARBALDEHYDE

Synonyms: SBB000302;ZINC00061503;AKOS AU36-M569;390119_ALDRICH;ASISCHEM C51996;AKOS BBS-00001118;RARECHEM AK ML 0551;TIMTEC-BB SBB000302;IFLAB-BB F0010-0600;2-Chloro-3-formylquinoline

CBNumber:: CB1451393

Molecular Formula:: C10H6ClNO

Molecular Weight:: 191.61

MDL Number:: MFCD00130079

MOL File:: 73568-25-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-04-24 14:58:19

Product description	Number	Pack Size	Price
2-Chloro-3-quinolinecarboxaldehyde 98%	390119	1g	$33
2-Chloro-3-quinolinecarboxaldehyde 98%	390119	10g	$165
2-Chloro-3-quinolinecarboxaldehyde >98.0%(GC)	C2289	1g	$19
2-Chloro-3-quinolinecarboxaldehyde >98.0%(GC)	C2289	5g	$55
2-CHLOROQUINOLINE-3-CARBALDEHYDE 95%	50954	5G	$35
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2-CHLOROQUINOLINE-3-CARBALDEHYDE Properties

Melting point	148-150 °C (lit.)
Boiling point	335.8±22.0 °C(Predicted)
Density	1.364
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
pka	-1.31±0.50(Predicted)
form	Liquid
color	Clear colorless to yellow
Sensitive	Air Sensitive
InChI	1S/C10H6ClNO/c11-10-8(6-13)5-7-3-1-2-4-9(7)12-10/h1-6H
InChIKey	SDKQWXCBSNMYBN-UHFFFAOYSA-N
SMILES	Clc1nc2ccccc2cc1C=O
CAS DataBase Reference	73568-25-9(CAS DataBase Reference)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-37/39

WGK Germany

HS Code

29334900

Storage Class

11 - Combustible Solids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	1
2		0

2-CHLOROQUINOLINE-3-CARBALDEHYDE price More Price(42)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	390119	2-Chloro-3-quinolinecarboxaldehyde 98%	73568-25-9	1g	$33	2023-01-07	Buy
Sigma-Aldrich	390119	2-Chloro-3-quinolinecarboxaldehyde 98%	73568-25-9	10g	$165	2023-01-07	Buy
TCI Chemical	C2289	2-Chloro-3-quinolinecarboxaldehyde >98.0%(GC)	73568-25-9	1g	$19	2026-04-30	Buy
TCI Chemical	C2289	2-Chloro-3-quinolinecarboxaldehyde >98.0%(GC)	73568-25-9	5g	$55	2026-04-30	Buy
AstaTech	50954	2-CHLOROQUINOLINE-3-CARBALDEHYDE 95%	73568-25-9	5G	$35	2026-04-30	Buy

Product number	Packaging	Price	Buy
390119	1g	$33	Buy
390119	10g	$165	Buy
C2289	1g	$19	Buy
C2289	5g	$55	Buy
50954	5G	$35	Buy

2-CHLOROQUINOLINE-3-CARBALDEHYDE Chemical Properties,Uses,Production

Chemical Properties

Yellow to yellow-brown crystalline powder

Synthesis

612-62-4

73568-25-9

Example 7 Synthesis of 2-chloro-3-quinolinecarboxaldehyde: 1.53 mL (3.30 mmol) of n-butyllithium (n-BuLi) was added slowly and dropwise to an 8 mL THF solution containing 0.46 mL (3.30 mmol) of diisopropylamine at 0 °C. After 20 minutes of reaction, the solution was cooled to -78 °C and 2-chloroquinoline (491 mg, 3.0 mmol) was added at this temperature. The mixture was stirred at -78 °C for 30 min, followed by dropwise addition of dimethylformamide (0.39 mL, 5.04 mmol) and continued stirring at the same temperature for 30 min. Upon completion of the reaction, the reaction was quenched with glacial acetic acid (1 mL) at -78 °C, then the mixture was slowly warmed to room temperature and diluted with ether (30 mL). The organic phase was washed sequentially with saturated NaHCO3 solution (10 mL) and brine (10 mL) and dried over anhydrous MgSO4. Concentration gave 2-chloro-3-quinolinecarboxaldehyde (530 mg, 92% yield) as a light yellow solid with melting point 145-149 °C, which could be used in the next reaction without further purification. By recrystallization from ethyl acetate, a pure product was obtained as pale yellow acicular crystals with a melting point of 149-150 °C (literature values 148-149 °C, see Meth-Cohn, O.; Narhe, B.; Tarnowski, B. J. Chem. Soc. Perkin Trans. I 1981, 1520).1H NMR (300 MHz, CDCl3) δ 10.57 (s, 1H), 8.77 (s, 1H), 8.08 (d, 1H, J = 9 Hz), 8.0 (d, 1H, J = 9 Hz), 7.90 (t, 1H, J = 9 Hz), 7.67 (t, 1H, J = 9 Hz); IR (nujol) 1685, 1575, 1045, 760, 745 cm-1. 745 cm-1.

References

[1] Patent: US5212317, 1993, A
[2] Patent: US5162532, 1992, A

2-CHLOROQUINOLINE-3-CARBALDEHYDE synthesis

Synthesis of 2-CHLOROQUINOLINE-3-CARBALDEHYDE from 2-Chloroquinoline

2-CHLOROQUINOLINE-3-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

2-Chloroquinoline (2-CHLORO-3-QUINOLINYL)METHANOL Acetophenone oxime 2-CHLORO-3-QUINOLINECARBOXALDEHYDE OXIME DIETHYL HYDRAZODICARBOXYLATE

Diethyl azodicarboxylate Aniline Acetanilide 2-METHYLACETANILIDE Acetic anhydride

Ethyl formate

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Preparation Products

2-MORPHOLIN-4-YL-QUINOLINE-3-CARBALDEHYDE Acridin-3-ol

2-CHLOROQUINOLINE-3-CARBALDEHYDE Suppliers

Global( 221)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	+86-86-13131129325 +8613131129325	sales1@chuanghaibio.com	China	5235	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21590	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29819	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
Hebei Zhanyao Biotechnology Co. Ltd	15369953316 +8615369953316	admin@zhanyaobio.com	China	2123	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58

Supplier	Advantage
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Hebei Zhanyao Biotechnology Co. Ltd	58
Dideu Industries Group Limited	58

View Lastest Price from 2-CHLOROQUINOLINE-3-CARBALDEHYDE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-11-18	2-CHLOROQUINOLINE-3-CARBALDEHYDE 73568-25-9	US $1.10 / g	1g	99.00%	100 Tons	Dideu Industries Group Limited
2025-06-27	2-CHLOROQUINOLINE-3-CARBALDEHYDE 73568-25-9	US $0.00-0.00 / KG	1KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd
2025-05-26	2-CHLOROQUINOLINE-3-CARBALDEHYDE 73568-25-9	US $30.00-10.00 / kg	10kg	99%	100000kg	Hebei Chuanghai Biotechnology Co,.LTD

2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
US $1.10 / g
99.00%
Dideu Industries Group Limited

2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
US $30.00-10.00 / kg
99%
Hebei Chuanghai Biotechnology Co,.LTD

2-CHLOROQUINOLINE-3-CARBALDEHYDE Spectrum

2-CHLOROQUINOLINE-3-CARBALDEHYDE(73568-25-9)FT-IR 2-CHLOROQUINOLINE-3-CARBALDEHYDE(73568-25-9)IR 2-CHLOROQUINOLINE-3-CARBALDEHYDE(73568-25-9)Raman

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2-CHLORO-6-(ETHYLOXY)QUINOLINE-3-CARBALDEHYDE 2-CHLORO-6,7-DIMETHOXY-QUINOLINE-3-CARBALDEHYDE 2,4-DICHLOROQUINOLIN-3-CARBOXALDEHYDE 2-CHLORO-8-METHYL-3-QUINOLINE CARBOXALDEHYDE 2-CHLORO-5,6,7-TRIMETHOXY-QUINOLINE-3-CARBALDEHYDE

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TIMTEC-BB SBB000302 RARECHEM AK ML 0551 2-CHLOROQUINOLINE-3-CARBALDEHYDE 2-CHLOROQUINOLINE-3-CARBOXALDEHYDE 2-CHLORO-3-QUINOLINECARBOXALDEHYDE ASISCHEM C51996 IFLAB-BB F0010-0600 AKOS AU36-M569 AKOS BBS-00001118 2-Chloro-3-formylquinoline 2-Chloro-3-quinolinecarbaldehyde 2-Chloro-3-quinolinecarboxaldehyde,98% 2-Chloro-3-quinolinecarboxaldehyde 98% 390119_ALDRICH SBB000302 ZINC00061503 JRH-03801, 2-Chloroquinoline-3-carbaldehyde, 97% 2-Chloro-3-quinolinecarboxaldehyde > 3-Quinolinecarboxaldehyde, 2-chloro- 2-CHLOROQUINOLINE-3-CARBALDEHYDE ISO 9001：2015 REACH 73568-25-9 73568-28-9 C10H6NOCl C10H6ClNO ARYL ALDEHYDE Building Blocks Heterocyclic Building Blocks Halogenated Heterocycles Quinolines Halogenated Heterocycles Heterocyclic Building Blocks Quinolines QuinolinesHeterocyclic Building Blocks Building Blocks