2-CHLOROQUINOLINE-3-CARBALDEHYDE
- CAS No.
- 73568-25-9
- Chemical Name:
- 2-CHLOROQUINOLINE-3-CARBALDEHYDE
- Synonyms
- SBB000302;ZINC00061503;AKOS AU36-M569;390119_ALDRICH;ASISCHEM C51996;AKOS BBS-00001118;RARECHEM AK ML 0551;TIMTEC-BB SBB000302;IFLAB-BB F0010-0600;2-Chloro-3-formylquinoline
- CBNumber:
- CB1451393
- Molecular Formula:
- C10H6ClNO
- Molecular Weight:
- 191.61
- MDL Number:
- MFCD00130079
- MOL File:
- 73568-25-9.mol
- MSDS File:
- SDS
| Melting point | 148-150 °C (lit.) |
|---|---|
| Boiling point | 335.8±22.0 °C(Predicted) |
| Density | 1.364 |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| pka | -1.31±0.50(Predicted) |
| form | Liquid |
| color | Clear colorless to yellow |
| Sensitive | Air Sensitive |
| InChIKey | SDKQWXCBSNMYBN-UHFFFAOYSA-N |
| CAS DataBase Reference | 73568-25-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29334900 | |||||||||
| NFPA 704 |
|
2-CHLOROQUINOLINE-3-CARBALDEHYDE price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 390119 | 2-Chloro-3-quinolinecarboxaldehyde 98% | 73568-25-9 | 1g | $33 | 2023-01-07 | Buy |
| Sigma-Aldrich | 390119 | 2-Chloro-3-quinolinecarboxaldehyde 98% | 73568-25-9 | 10g | $165 | 2023-01-07 | Buy |
| TCI Chemical | C2289 | 2-Chloro-3-quinolinecarboxaldehyde >98.0%(GC) | 73568-25-9 | 1g | $20 | 2024-03-01 | Buy |
| TCI Chemical | C2289 | 2-Chloro-3-quinolinecarboxaldehyde >98.0%(GC) | 73568-25-9 | 5g | $59 | 2024-03-01 | Buy |
| Alfa Aesar | H27133 | 2-Chloroquinoline-3-carboxaldehyde, 98% | 73568-25-9 | 1g | $35.65 | 2024-03-01 | Buy |
2-CHLOROQUINOLINE-3-CARBALDEHYDE Chemical Properties,Uses,Production
Chemical Properties
Yellow to yellow-brown crystalline powder
Synthesis
612-62-4
73568-25-9
Example 7 Synthesis of 2-chloro-3-quinolinecarboxaldehyde: 1.53 mL (3.30 mmol) of n-butyllithium (n-BuLi) was added slowly and dropwise to an 8 mL THF solution containing 0.46 mL (3.30 mmol) of diisopropylamine at 0 °C. After 20 minutes of reaction, the solution was cooled to -78 °C and 2-chloroquinoline (491 mg, 3.0 mmol) was added at this temperature. The mixture was stirred at -78 °C for 30 min, followed by dropwise addition of dimethylformamide (0.39 mL, 5.04 mmol) and continued stirring at the same temperature for 30 min. Upon completion of the reaction, the reaction was quenched with glacial acetic acid (1 mL) at -78 °C, then the mixture was slowly warmed to room temperature and diluted with ether (30 mL). The organic phase was washed sequentially with saturated NaHCO3 solution (10 mL) and brine (10 mL) and dried over anhydrous MgSO4. Concentration gave 2-chloro-3-quinolinecarboxaldehyde (530 mg, 92% yield) as a light yellow solid with melting point 145-149 °C, which could be used in the next reaction without further purification. By recrystallization from ethyl acetate, a pure product was obtained as pale yellow acicular crystals with a melting point of 149-150 °C (literature values 148-149 °C, see Meth-Cohn, O.; Narhe, B.; Tarnowski, B. J. Chem. Soc. Perkin Trans. I 1981, 1520).1H NMR (300 MHz, CDCl3) δ 10.57 (s, 1H), 8.77 (s, 1H), 8.08 (d, 1H, J = 9 Hz), 8.0 (d, 1H, J = 9 Hz), 7.90 (t, 1H, J = 9 Hz), 7.67 (t, 1H, J = 9 Hz); IR (nujol) 1685, 1575, 1045, 760, 745 cm-1. 745 cm-1.
References
[1] Patent: US5212317, 1993, A
[2] Patent: US5162532, 1992, A
2-CHLOROQUINOLINE-3-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mujin Biotechnology Co.,Ltd | +86-13288715578 | sales@hbmojin.com | China | 12648 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5251 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21622 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
View Lastest Price from 2-CHLOROQUINOLINE-3-CARBALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-07-07 | 2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mujin Biotechnology Co.,Ltd | |
 |
2025-06-27 | 2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-05-26 | 2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
|
US $30.00-10.00 / kg | 10kg | 99% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- 2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
- US $0.00 / KG
- 99%
- Hebei Mujin Biotechnology Co.,Ltd
-
- 2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 2-CHLOROQUINOLINE-3-CARBALDEHYDE
73568-25-9
- US $30.00-10.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
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