ChemicalBook >> CAS DataBase List >>N-acetyl aspartyl-glutaMic acid

N-acetyl aspartyl-glutaMic acid

CAS No.
3106-85-2
Chemical Name:
N-acetyl aspartyl-glutaMic acid
Synonyms
NAAG;NAAGA;Naaxia;α-NAAG;ZY-15106;AC-ASP-GLU;ALPHA-NAAG;ACETYL-D-E;AC-ASP-GLU-OH;AC-ASP-GLU H2O
CBNumber:
CB1742046
Molecular Formula:
C11H16N2O8
Molecular Weight:
304.25
MDL Number:
MFCD00076652
MOL File:
3106-85-2.mol
Last updated:2023-06-30 15:45:59

N-acetyl aspartyl-glutaMic acid Properties

Melting point 171-173 °C
Boiling point 769.5±60.0 °C(Predicted)
Density 1.472±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility H2O: 50 mg/mL
pka 3.04±0.10(Predicted)
form powder
color white
optical activity [α]22/D 34.5°, c = 1.1 in H2O(lit.)
Water Solubility Soluble to 100 mM in water
Stability Hygroscopic
FDA UNII 1W8M12WXYL
ATC code R01AC05,S01GX03

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
HS Code  29241990
NFPA 704
0
2 0

N-acetyl aspartyl-glutaMic acid price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A5930 N-Acetyl-Asp-Glu ≥97% (TLC), powder 3106-85-2 25mg $137 2024-03-01 Buy
Sigma-Aldrich A5930 N-Acetyl-Asp-Glu ≥97% (TLC), powder 3106-85-2 100mg $384 2024-03-01 Buy
Usbiological 166584 Spaglumic Acid 3106-85-2 50mg $403 2021-12-16 Buy
TRC S679100 SpaglumicAcid 3106-85-2 50mg $50 2021-12-16 Buy
Biosynth Carbosynth FA05316 N-Acetyl-L-aspartyl-L-glutamic acid 3106-85-2 100mg $65 2021-12-16 Buy
Product number Packaging Price Buy
A5930 25mg $137 Buy
A5930 100mg $384 Buy
166584 50mg $403 Buy
S679100 50mg $50 Buy
FA05316 100mg $65 Buy

N-acetyl aspartyl-glutaMic acid Chemical Properties,Uses,Production

Chemical Properties

White powder

Uses

N-Acetyl-Asp-Glu has been used in N-acetylated α-linked acidic dipeptidase (NAALADase) assay and affinity experiments.

Uses

N-acetyl aspartyl-glutamic acid is a spaglumic acid is a marker of neuronal integrity and was used in the detection of therapeutic values of antidrepressant treatments.

Definition

ChEBI: A dipeptide composed of N-acetyl-L-aspartic acid and L-glutamic acid joined by a peptide linkage.

General Description

NAAG is a neuropeptide and a neurotransmitter that is abundant in the mammalian nervous system. It remains uncertain whether this compound activates NMDA receptors; however, it is clearly demonstrated to act as a selective agonist of mGluR3, both in vitro and in vivo.

Biochem/physiol Actions

Endogenous neurotransmitter localized to neurons with high affinity for metabotropic glutamate receptors, mGluR3. It is an antagonist at NMDA receptors. Catabolized by carboxypeptidase II, which is expressed on astrocyte membranes, to N-acetylaspartate and glutamate.

storage

-20°C

N-acetyl aspartyl-glutaMic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 127)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29067 58
BOC Sciences
+16314854226 inquiry@bocsci.com United States 19743 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
Hangzhou Go Top Peptide Biotech
0571-88211921 sales1@gotopbio.com CHINA 2609 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634 Cecilia@youngshechem.com China 2345 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503259 +86-19930503259 cherry@crovellbio.com China 18455 58
Nanjing TGpeptide
+86-13347807150 +86-13347807150 support@tgpeptide.com China 3279 58
Zhejiang Hangyu API Co., Ltd
+8617531972939 anna@api-made.com China 2944 58

N-acetyl aspartyl-glutaMic acid Spectrum

SPAGLUMIC ACID NAAG N-ACETYL-L-ASPARTYL-L-GLUTAMIC ACID N-ACETYLASPARTYLGLUTAMIC ACID N-ACETYL-ASP-GLU N-ACETYL-ASP-GLU-OH ALPHA-NAAG AC-ASP-GLU AC-ASP-GLU H2O AC-ASP-GLU-OH n-acetyl-1-aspartylglutamicacid isospaglumic acid Naaxia 2-[(2-acetamido-3-carboxy-propanoyl)amino]pentanedioic acid ACETYL-D-E NAAG, Spaglumic acid NAAGA ZY-15106 6-AMINO-1-HEXANETHIOL,HCL (S)-2-((S)-2-acetaMido-3-carboxypropanaMido)pentanedioic acid NAAG - CAS 3106-85-2 - Calbiochem N-acetyl aspartyl-glutaMic acid USP/EP/BP L-Glutamic acid, N-acetyl-L-α-aspartyl- (S)-2-((S)-2-Acetamido-3-carboxypropanamido)pentanedioic acid[Spaglumic Acid α-NAAG 3106-85-2 3106-86-2 C11H16N2O8