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Flutoprazepam

CAS No.
25967-29-7
Chemical Name:
Flutoprazepam
Synonyms
Restas;Restar;KB-509;KB-509P;ID-1937;Flutoprazepam;Flutoprazepamum;2H-1,4-BENZODIAZEPIN-2-ONE;7-Chloro-1-(cyclopropylMethyl)-5-(2-fluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one;7-Chloro-1-(cyclopropylmethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
CBNumber:
CB2125099
Molecular Formula:
C19H16ClFN2O
Molecular Weight:
342.79
MDL Number:
MFCD00866972
MOL File:
25967-29-7.mol
Last updated:2023-06-12 18:01:47

Flutoprazepam Properties

Melting point 118-122°
Boiling point 539.3±50.0 °C(Predicted)
Density 1.2683 (estimate)
solubility DMF: 30 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml
form A crystalline solid
pka 1.93±0.35(Predicted)
FDA UNII 2GHY1101MM

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332
Precautionary statements  P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P321-P330-P362+P364-P501
Toxicity LD50 in male, female mice, rats (mg/kg): 2640, 2430, 13760, 10060 orally; 2400, 2110, 2460, 2230 i.p.; >5000 s.c. all species (Takebe)
NFPA 704
0
3 0

Flutoprazepam Chemical Properties,Uses,Production

Description

Flutoprazepam is a benzodiazepine anti-anxiety agent, somewhat longer acting and more potent than diazepam.

Originator

Sumitomo (Japan)

Uses

Flutoprazepam, is a drug of a benzodiazepine class. It has shown to have muscle relaxant properties almost equivalent to Diazepam (D416855), however having more powerful sedative, hypnotic, anxiolytic and anticonvulsant effects.

Definition

ChEBI: Flutoprazepam is an organic molecular entity.

brand name

RESTAS

Flutoprazepam Preparation Products And Raw materials

Raw materials

Preparation Products

2H-1,4-BENZODIAZEPIN-2-ONE, 7-CHLORO-1-(CYCLOPROPYLMETHYL)-5-(2-FLUOROPHENYL)-1,3-DIHYDRO- Flutoprazepam ID-1937 KB-509 Restar Restas KB-509P 7-Chloro-1-(cyclopropylMethyl)-5-(2-fluorophenyl)-1H-benzo[e][1,4]diazepin-2(3H)-one 2H-1,4-BENZODIAZEPIN-2-ONE 7-Chloro-1-(cyclopropylmethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one Flutoprazepamum 25967-29-7 C19H16ClFN2O