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Nabumetone

Nabumetone
Nabumetone structure
CAS No.
42924-53-8
Chemical Name:
Nabumetone
Synonyms
relifex;RELAFEN;brl147777;Nabumeton;BRL-14777;NABUMETONE;Nabumetone (DMF);Nabumetone (200 mg);NABUMETONE, BP STANDARD;NABUMETONE, EP STANDARD
CBNumber:
CB2386779
Molecular Formula:
C15H16O2
Formula Weight:
228.29
MOL File:
42924-53-8.mol

Nabumetone Properties

Melting point:
80-810C
Boiling point:
330.1°C (rough estimate)
Density 
1.0657 (rough estimate)
refractive index 
1.5542 (estimate)
storage temp. 
Refrigerator
solubility 
Soluble in alcohol or chloroform
form 
neat
CAS DataBase Reference
42924-53-8(CAS DataBase Reference)
NIST Chemistry Reference
Nabumetone(42924-53-8)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22-40
Safety Statements  36/37
WGK Germany  2
RTECS  EL9085000
Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H303 May be harmfulif swallowed Acute toxicity,oral Category 5 P312
Precautionary statements:

Nabumetone price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N6142 Nabumetone analytical standard 42924-53-8 5g $110 2018-11-20 Buy
Sigma-Aldrich 1449518 Nabumetone United States Pharmacopeia (USP) Reference Standard 42924-53-8 200mg $352.8 2018-11-20 Buy
Alfa Aesar J63072 Nabumetone 42924-53-8 5g $85.2 2018-11-13 Buy
Alfa Aesar J63072 Nabumetone 42924-53-8 25g $278 2018-11-13 Buy
Cayman Chemical 20251 Nabumetone ≥98% 42924-53-8 1g $25 2018-11-19 Buy

Nabumetone Chemical Properties,Uses,Production

Description

Nabumetone is a non-acidic, nonsteroidal antiinflammatory agent formally related to naproxen. Its main circulating metabolite is 6-methoxy-2-naphthylacetic acid (α-nornaproxen). Administered once daily (Tsub>1/2 * 30 hrs), nabumetone is reported to be effective in the treatment of rheumatoid and osteoarthritis.

Chemical Properties

White Powder

Originator

Beecham (United Kingdom)

Uses

Anti-inflamatory. Antibacterial

Uses

Anti-inflammatory. Antibacterial.

Uses

anesthetic (local)

Definition

ChEBI: A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is s own to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.

brand name

Relafen (Smith-Kline Beecham);RELIFEX.

General Description

Nabumetone (Relafen), a nonacidic NSAID prodrug, isclassified as an arylacetic acid, because it undergoes rapidhepatic metabolism to its active metabolite, 6-methoxy-2-naphthylacetic acid. Similar to the other arylacetic aciddrugs, it is used in short- or long-term management of RAand OA. Being nonacidic, it does not produce significantprimary insult to the GI mucosa lining and also has no effecton prostaglandin synthesis in gastric mucosa, thus producingminimum secondary GI damage when comparedwith other conventional NSAIDs.

Nabumetone Preparation Products And Raw materials

Raw materials

Preparation Products


Nabumetone Suppliers

Global( 162)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20229 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15926 69
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078,021-50426030
86-021-50426522,50426273 sales@jingyan-chemical.com China 10073 60
LGM Pharma 1-(800)-881-8210
615-250-9817 inquiries@lgmpharma.com United States 1954 70

View Lastest Price from Nabumetone manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Nabumetone
42924-53-8
US $1.00 / KG 1G 98% 100KG career henan chemical co

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