D(-)-Arginine
- CAS No.
- 157-06-2
- Chemical Name:
- D(-)-Arginine
- Synonyms
- D-ARGININE;H-D-ARG-OH;D-ARG;D-Arg-OH;D-Arginin;H-D-Arginine;ARGININE, D-;R-(-)-ARGININE;D-(-)-ARGININE;D-Arginine,98%
- CBNumber:
- CB2408147
- Molecular Formula:
- C6H14N4O2
- Molecular Weight:
- 174.2
- MDL Number:
- MFCD00063116
- MOL File:
- 157-06-2.mol
- MSDS File:
- SDS
Melting point | 226 °C (dec.) (lit.) |
---|---|
alpha | -28.5 º (c=8, 6 N HCl) |
Boiling point | 305.18°C (rough estimate) |
Density | 1.2297 (rough estimate) |
refractive index | -23 ° (C=8, 6mol/L HCl) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | Aqueous Acid (Slightly), Water (Slightly) |
form | Solid |
pka | 2.49±0.24(Predicted) |
color | White to Off-White |
Water Solubility | SOLUBLE |
Sensitive | Air Sensitive |
BRN | 1725412 |
InChIKey | ODKSFYDXXFIFQN-SCSAIBSYSA-N |
LogP | -0.999 (est) |
CAS DataBase Reference | 157-06-2(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | R54Z304Z7C |
EPA Substance Registry System | D-Arginine (157-06-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H319 | |||||||||
Precautionary statements | P264-P280i-P337+P313-P305+P351+P338 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36-36/37/38-20/21/22 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | CF1934220 | |||||||||
F | 9 | |||||||||
TSCA | Yes | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29252000 | |||||||||
NFPA 704 |
|
D(-)-Arginine price More Price(40)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A2646 | D-Arginine ≥98% (TLC) | 157-06-2 | 1g | $106 | 2024-03-01 | Buy |
Sigma-Aldrich | A2646 | D-Arginine ≥98% (TLC) | 157-06-2 | 5g | $364 | 2024-03-01 | Buy |
TCI Chemical | A1029 | D-(-)-Arginine >98.0%(T) | 157-06-2 | 1g | $57 | 2024-03-01 | Buy |
TCI Chemical | A1029 | D-(-)-Arginine >98.0%(T) | 157-06-2 | 5g | $196 | 2024-03-01 | Buy |
Alfa Aesar | A16137 | D-Arginine, 98% | 157-06-2 | 1g | $61.65 | 2024-03-01 | Buy |
D(-)-Arginine Chemical Properties,Uses,Production
Description
D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine.
Chemical Properties
white to light yellow crystal powde
Uses
1-Deamino-8-D-arginine vasopressin makes a new pharmacological approach to the management of haemophilia and von Willebrand's disease. A novel nonenzymatic pathway for the generation of nitric oxide is by the reaction of hydrogen peroxide and d- or l-arginine.
Uses
Arginine is an essential amino acid found in food and plant sources, and many biological systems.
D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man.
D-Arginine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. D-Arginine specifically can inhibit arginine decarboxylase enzymes and also functions as a metabolite.
Definition
ChEBI: A D-alpha-amino acid that is the D-isomer of arginine.
References
https://www.alfa.com/zh-cn/catalog/A16137/
Iannucci, N. B., et al. "Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells." Future Medicinal Chemistry 3.16(2011):1987-1993.
Ripoll, Giselle, et al. "Angiostatic activity of 1-Deamino-8-D-Arginine vasopressin and novel peptide analogues in breast cancer cells." Cancer Research 68(2008).
Navarro, Eduardo, et al. "Toxicological and Pharmacological Effects of D-Arginine." Basic & Clinical Pharmacology & Toxicology97.3(2005):149-154.
D(-)-Arginine Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | info@fortunachem.com | China | 5987 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 2990 | 58 |
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | +8615383190639 | admin@86-ss.com | China | 1000 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18629 | 58 |
Taizhou Tianhong Biochemistry Technology Co., Ltd. | 0523-86132544 | sales@thbiochem.com | CHINA | 305 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9355 | 55 |
Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
View Lastest Price from D(-)-Arginine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-18 | D(-)-Arginine
157-06-2
|
US $0.00-0.00 / kg | 1kg | 98%min | 500kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-09-18 | D(-)-Arginine
157-06-2
|
US $999.00-800.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | ||
2024-09-18 | D(-)-Arginine
157-06-2
|
US $100.00-75.00 / kg | 1kg | 99% | 5000 | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD |
- D(-)-Arginine
157-06-2
- US $0.00-0.00 / kg
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- D(-)-Arginine
157-06-2
- US $999.00-800.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
- D(-)-Arginine
157-06-2
- US $100.00-75.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
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