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6-Aminocaproic acid

Description References
6-Aminocaproic acid
6-Aminocaproic acid
CAS No.
60-32-2
Chemical Name:
6-Aminocaproic acid
Synonyms
ACS;EACS;EACA;177jd;cy116;Hepin;Amikar;Amicar;CY 116;177 J.D
CBNumber:
CB5223888
Molecular Formula:
C6H13NO2
Formula Weight:
131.17
MOL File:
60-32-2.mol

6-Aminocaproic acid Properties

Melting point:
207-209 °C (dec.)(lit.)
Boiling point:
242.49°C (rough estimate)
Density 
1.03 g/mL at 20 °C
refractive index 
1.4870 (estimate)
Flash point:
207-209°C
storage temp. 
2-8°C
solubility 
H2O: 50 mg/mL
form 
powder
pka
4.373(at 25℃)
color 
white
PH
7.0-7.5 (50g/l, H2O, 20℃)
Water Solubility 
SOLUBLE
Merck 
14,432
BRN 
906872
CAS DataBase Reference
60-32-2(CAS DataBase Reference)
NIST Chemistry Reference
Hexanoic acid, 6-amino-(60-32-2)
EPA Substance Registry System
Hexanoic acid, 6-amino-(60-32-2)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  MO6300000
TSCA  Yes
HS Code  29224995
Hazardous Substances Data 60-32-2(Hazardous Substances Data)
Toxicity LD50 in rats (g/kg): 7.0 i.p.; ~3.3 i.v. (Hallesy)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

6-Aminocaproic acid price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 07260 6-Aminohexanoic acid ≥98.5% (NT) 60-32-2 100g $103 2018-11-13 Buy
Sigma-Aldrich 07260 6-Aminohexanoic acid ≥98.5% (NT) 60-32-2 1kg $383 2018-11-13 Buy
TCI Chemical A0312 6-Aminohexanoic Acid >98.0%(T) 60-32-2 25g $23 2018-11-22 Buy
TCI Chemical A0312 6-Aminohexanoic Acid >98.0%(T) 60-32-2 500g $266 2018-11-22 Buy
Alfa Aesar A14719 6-Aminohexanoic acid, 99% 60-32-2 100g $27.5 2018-11-13 Buy

6-Aminocaproic acid Chemical Properties,Uses,Production

Description

6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.

References

https://pubchem.ncbi.nlm.nih.gov/compound/6-aminohexanoic_acid#section=Pharmacology-and-Biochemistry
https://en.wikipedia.org/wiki/Aminocaproic_acid

Chemical Properties

white crystalline powder

Uses

hemostatic

Uses

6-Aminohexanoic Acid is a reagent commonly used for the extraction of aldehydes from reaction mixtures. 6-Aminohexanoic Acid has also been shown to improve solubilization of membrane proteins in elect rophoresis. Studies suggest that 6-Aminohexanoic Acid inhibits the activation of the first component of the complement system.

Uses

Propylparaben Food preservative

Uses

EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.

Definition

ChEBI: An amino-acid anion that is the conjugate base of 6-aminohexanoic acid.

brand name

Amicar (Xanodyne).

Safety Profile

Moderately toxic by intravenous route. Human systemic effects by ingestion: changes in tubules (includmg acute renal failure, acute tubular necrosis), hematuria, and increased body temperature. Experimental reproductive effects. An eye irritant. When heated to decomposition it emits toxic fumes such as NOx,.

6-Aminocaproic acid Preparation Products And Raw materials

Raw materials

Preparation Products


6-Aminocaproic acid Suppliers

Global( 349)Suppliers
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career henan chemical co
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Chemspon Bio-Tech Co., Ltd 0571-88937695 88937835
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View Lastest Price from 6-Aminocaproic acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-23 6-Aminocaproic acid
60-32-2
US $40.00-308.00 / KG 1KG 99 200kg career henan chemical co

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