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1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride structure

CAS No.: 70918-74-0

Chemical Name:: 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride

Synonyms: TIMTEC-BB SBB003004;Doxazosin iMpurity B;Doxazosin EP IMpurity B;Doxazosin Related CoMpound A;Doxazosin EP Impurity B(HCl);1-[(2RS)-2,3-Dihydro-1,4-benzodioxi;Doxazosin EP Impurity B Hydrochloride;1,4-BENZODIOXAN-2-CARBONYL PIPERAZINE HCL;Doxazosin EP Impurity B monohydrochloride;1-(1,4-Benzodioxan-2-carbonyl)piperazine*HCl

CBNumber:: CB2419783

Molecular Formula:: C13H17ClN2O3

Molecular Weight:: 284.74

MDL Number:: MFCD00729051

MOL File:: 70918-74-0.mol

Last updated:2025-07-04 15:13:15

Product description	Number	Pack Size	Price
Doxazosin Related Compound A certified reference material, pharmaceutical secondary standard	PHR3313	50MG	$592
Doxazosin Related Compound A	1225420	20mg	$1300
2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride >98.0%(HPLC)	P1890	5g	$27
2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride >98.0%(HPLC)	P1890	25g	$85
1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazineMonohydrochloride	D448445	5g	$165
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1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride Properties

Melting point	105-108°C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	powder to crystal
color	White to Almost white
Stability	Hygroscopic
InChI	InChI=1S/C13H16N2O3.ClH/c16-13(15-7-5-14-6-8-15)12-9-17-10-3-1-2-4-11(10)18-12;/h1-4,12,14H,5-9H2;1H
InChIKey	TUKBWYXLYINULI-UHFFFAOYSA-N
SMILES	C12=CC=CC=C1OCC(C(=O)N1CCNCC1)O2.Cl
CAS DataBase Reference	70918-74-0(CAS DataBase Reference)
EWG's Food Scores	1
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS06,GHS08,GHS09

Signal word

Danger

Hazard statements

H301+H311+H331-H373-H411

Precautionary statements

P273-P280-P301+P310-P302+P352+P312-P304+P340+P311-P314

Hazard Codes

T;N,Xi,N,T

Risk Statements

23/24/25-48/22-51/53

Safety Statements

45-53-61

RIDADR

UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all

Hazard Note

Irritant

HazardClass

6.1

PackingGroup

III

HS Code

2934990002

NFPA 704

	0
2		0

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride price More Price(32)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR3313	Doxazosin Related Compound A certified reference material, pharmaceutical secondary standard	70918-74-0	50MG	$592	2025-07-31	Buy
Sigma-Aldrich	1225420	Doxazosin Related Compound A	70918-74-0	20mg	$1300	2025-07-31	Buy
TCI Chemical	P1890	2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride >98.0%(HPLC)	70918-74-0	5g	$27	2025-07-31	Buy
TCI Chemical	P1890	2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride >98.0%(HPLC)	70918-74-0	25g	$85	2025-07-31	Buy
TRC	D448445	1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazineMonohydrochloride	70918-74-0	5g	$165	2021-12-16	Buy

Product number	Packaging	Price	Buy
PHR3313	50MG	$592	Buy
1225420	20mg	$1300	Buy
P1890	5g	$27	Buy
P1890	25g	$85	Buy
D448445	5g	$165	Buy

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride Chemical Properties,Uses,Production

Uses

1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride (Doxazosin EP Impurity B) is an impurity of Doxazosin (D537500), a selective a1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride synthesis

Synthesis of 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride from Piperazine and Ethyl 1,4-Benzodioxan-2-carboxylate

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride Preparation Products And Raw materials

Raw materials

Ethyl 1,4-Benzodioxan-2-carboxylate 2,3-DIHYDRO-1,4-BENZODIOXINE-2-CARBONYL CHLORIDE 2-HYDROXYMETHYL-1,4-BENZODIOXANE Piperazine

Preparation Products

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride Suppliers

Global( 227)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	722	55
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Standardpharm Co. Ltd.	86-714-3992388	overseasales1@yongstandards.com	United States	14332	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Wuhan Chemwish Technology Co., Ltd	027-67849912	sales@chemwish.com	CHINA	10821	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Finetech Industry Limited	+86-27-8746-5837 +8619945049750	info@finetechnology-ind.com	China	9629	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Chembon Pharmaceutical Co., Ltd.	55
Accela ChemBio Inc.	58
Standardpharm Co. Ltd.	58
Alchem Pharmtech,Inc.	58
Wuhan Chemwish Technology Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
SIMAGCHEM CORP	58
Finetech Industry Limited	58

View Lastest Price from 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-12-27	1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride 70918-74-0	US $1.00 / KG	1KG	99%	200kg	Career Henan Chemical Co

1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride
70918-74-0
US $1.00 / KG
99%
Career Henan Chemical Co

70918-74-0(1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride)Related Search:

Benzo[b]thien-2-ylboronic acid Piperazine citrate Dihydromyrcenol Dodecylbenzenesulphonic acid DODECYLBENZENE

CALCIUM DODECYLBENZENE SULFONATE Piperazine p-Phenylenediamine dihydrochloride Topotecan hydrochloride Doxazosin Related Compound F (15 mg) (N,N'-bis(1,4-benzodioxane-2-carbonyl)piperazine)

1-(1,4-Benzodioxane-2-carbonyl)piperazine 1,4-Benzodioxan Doxazosin 1-(CHLOROACETYL)-4-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)PIPERAZINE 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride

DOXAZOSIN MESILATE IMP. B (EP) AS HYDROCHLORIDE: 1-[(2RS)-2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL]PIPERAZINE HYDROCHLORIDE 1-(5-CHLORO-2-METHYLPHENYL)-4-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)PIPERAZINE 1-(3-CHLOROPHENYL)-4-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)PIPERAZINE

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1-(1,4-benzodioxan-2-ylcarbonyl)piperazine hydrochloride N-[(1,4-Benzodioxin-2-yl)carbonyl]piperazine hydrochloride 2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride 4-Benzodioxan-2-carbonyl)-piperazine hydrochloride Doxazosin Related Compound A (20 mg) (N-(1,4-benzodioxane-2-carbonyl)piperazine hydrochloride) Methanone,(2,3-dihydro-1,4-benzodioxin-2-yl)-1-piperazinyl-, hydrochloride (1:1) (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(piperazin-1-yl)Methanone hydrochloride N-(1,4-Benzodioxane-2-carbonyl)piperazine Hydrochloride Doxazosin EP IMpurity B N-[(1,4-Benzodioxane-2-yl)carboxyl] piperazine hydrochloride, >=98% N-(1,4-Benzodioxan-2-carbonyl)piperazinehydrochloride98% 1-(1,4-Benzodioxan-2-carbonyl)piperazine*HCl Doxazosin Related CoMpound A (2,3-Dihydrobenzo[1.4]dioxin-2-yl)piperazine-1-yl-methanone N-(2,3-Dihydro-1,4-Benzodioxane-2-Carbonyl)Piperazine HCl N-(1,4-Benzodioxan-2-carbonyl)piperazine hydrochloride 98% (2,3-Dihydro-benzo[1,4]dioxin-2-yl)piperazine- N-(1,4-BENZODIOXANE-2-CARBONYL) PIPERAZINE DIHYDRO 1-(2,3-DIHYDRO-1,4-BENZODIOXIN-2-YLCARBONYL)PIPERAZINE HCL RE-CREDIT RE-EXPORT OF QUALITY ISSUE-N (1 4 BENZODIOXAN-2-CARBONYL)-PIPERAZINE (2,3-DIHYDRO-BENZO[1,4]DIOXIN-2-YL)-PIPERAZIN-1-YL-METHANONE HYDROCHLORIDE (2,3-DIHYDRO-BENZO[1,4]DIOXIN-2-YL)PIPERAZINE-1-YL-METHANONE HYDROCHLORIDE 1,4-BENZODIOXAN-2-CARBONYL PIPERAZINE HCL 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride 1-(1,4-BENZODIOXANE-2-CARBONYL)PIPERAZINE HYDROCHLORIDE TIMTEC-BB SBB003004 N-(1,4-BENZODIOXAN-2-CARBONYL)-PIPERAZINE HCL N-(1,4-BENZODIOXAN-2-CARBONYL)PIPERAZINE HYDROCHLORIDE N-[(1,4-BENZODIOXANE-2-YL)CARBONYL]PIPERAZINE HCL N-[(1,4-BENZODIOXANE-2-YL)CARBOXYL] PIPERAZINE HYDROCHLORIDE N-(2,3-DIHYDRO-1,4-BENZODIOXANE-2-CARBONYL)PIPERAZINE HYDROCHLORIDE N-[(1,4-benzodioxane-2-yl)carbonyl]piperazine hydrochloride 1-[(1,4-Benzodioxane-2-Yl)Carboxyl]Piperazine Hydrochloride 2,3,4a,8a-tetrahydro-1,4-benzodioxin-3-yl(1-piperazinyl)methanone hydrochloride Doxazosin Impurity 2（Doxazosin EP Impurity B） Doxazosin EP Impurity B monohydrochloride (2,3-DIHYDRO-BENZO[1,4]DIOXIN-2-YL)-PIPERAZIN-1-YL-METHANONE HCL 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochlorid 2-(1-Piperazinylcarbonyl)-1,4-benzodioxaneHydrochloride> 1-[(2RS)-2,3-Dihydro-1,4-benzodioxi Doxazosin EP Impurity B Hydrochloride Doxazosin EP Impurity B/ Doxazosin Related Compund A 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydro... Doxazosin Related Compound A (N-(1,4-benzodioxane-2-carbonyl)piperazine hydrochloride) (1225420) Doxazosin EP Impurity B(HCl) Doxazosin USP Related Compound A as Hydrochloride Doxazosin Mesilate EP Impurity B as Hydrochloride Doxazosin EP Impurity B HCl (Doxazosin USP Related Compound A) 2-(1-Piperazinylcarbonyl)-1,4-benzodioxane Hydrochloride, ≥ 98.0% Doxazosin iMpurity B l-[(2,3-Dihydro-l,4-Benzodioxan-2-yl) Carbonyl] Piperazine 70918-74-0 C13H16N2O3HClC13H17ClN2O3 C13H16N2O3HClC13H17ClN2 C13H17N2O3Cl C13H16N2O3ClH (intermediate of doxazosin) (intermediate of doxazocin mesylate)