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Piperazine citrate

Chemical Name:
Piperazine citrate
ANTEPAR;Pinozan;PARAZINE;Patazine;Piperasol;Citraazine;Coliurinal;PIPERAZINE CITRATE;PiperazineCitrateBp;Tripiperazindicitrat
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
MSDS File:
Last updated:2024-07-25 20:04:51

Piperazine citrate Properties

Melting point 183-187℃
Boiling point 208℃[at 101 325 Pa]
Density 0.741[at 20℃]
vapor pressure 56.928Pa
storage temp. Inert atmosphere,Room Temperature
solubility Soluble in DMSO
form powder to crystal
color White to Almost white
Water Solubility 54g/L at 24℃
Merck 14,7464
LogP -1.15
CAS DataBase Reference 144-29-6(CAS DataBase Reference)
EPA Substance Registry System Piperazine, 2-hydroxy-1,2,3-propanetricarboxylate (3:2) (144-29-6)


Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
Signal word  Danger
Hazard statements  H317-H314-H319
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26
WGK Germany  1
RTECS  TL3485000
HS Code  29335990
NFPA 704
2 0

Piperazine citrate price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P2000000 Piperazine citrate European Pharmacopoeia (EP) Reference Standard 144-29-6 P2000000 $150 2024-03-01 Buy
TCI Chemical P0449 Piperazine Citrate Hydrate >98.0%(T) 144-29-6 25g $31 2024-03-01 Buy
TCI Chemical P0449 Piperazine Citrate Hydrate >98.0%(T) 144-29-6 500g $71 2024-03-01 Buy
TRC P479890 Piperazine citrate 144-29-6 25g $140 2021-12-16 Buy
TRC P479890 Piperazine citrate 144-29-6 100g $275 2021-12-16 Buy
Product number Packaging Price Buy
P2000000 P2000000 $150 Buy
P0449 25g $31 Buy
P0449 500g $71 Buy
P479890 25g $140 Buy
P479890 100g $275 Buy

Piperazine citrate Chemical Properties,Uses,Production


Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. First used as a solvent for uric acid, the use of piperazine as an anthelmintic agent was first introduced in 1953. Upon entry into the systemic circulation, the drug is partly oxidized and partly eliminated as an unchanged compound. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Piperazine was first introduced as an anthelmintic in 1953. Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.

Chemical Properties

Piperazine citrate is a white, crystalline powder, with not more than a slight odor. It is soluble in water, and insoluble in alcohol and in ether.


Piperazine Citrate is an anthelmintic agent used in the treatment of parasitic infections. Also used in the reduction of blood pressure.


Used as alternative treatment for ascariasis caused by Ascaris lumbricoides (roundworm) and enterobiasis (oxyuriasis) caused by Enterobius vermicularis (pinworm). It is also used to treat partial intestinal obstruction by the common roundworm, a condition primarily occurring in children.

brand name

Antepar (GlaxoSmithKline); Bryrel (Sanofi Aventis).

Flammability and Explosibility

Not classified

Mechanism of action

Piperazine is a GABA receptor agonist. Piperzine binds directly and selectively to muscle membrane GABA receptors, presumably causing hyperpolarization of nerve endings, resulting in flaccid paralysis of the worm. While the worm is paralyzed, it is dislodged from the intestinal lumen and expelled live from the body by normal intestinal peristalsis.


Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.

Piperazine citrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 232)Suppliers
Supplier Tel Email Country ProdList Advantage
Masteam Bio-tech Co., Ltd.
+86-15200345168 +86-15200345168 CHINA 153 58
Hebei Mojin Biotechnology Co., Ltd
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Hebei Guanlang Biotechnology Co,.LTD
+86-19930503253; +8619930503252 China 5852 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
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Henan Tianfu Chemical Co.,Ltd.
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career henan chemical co
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Jinan Shengqi pharmaceutical Co,Ltd
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View Lastest Price from Piperazine citrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Piperazine Citrate pictures 2024-07-25 Piperazine Citrate
US $10.00 / kg 1kg 98% 10 ton Hebei Guanlang Biotechnology Co,.LTD
Piperazine citrate pictures 2024-07-25 Piperazine citrate
US $0.00-0.00 / Kg/Drum 1KG 98.5%min 10 TONS WUHAN FORTUNA CHEMICAL CO., LTD
Piperazine Citrate pictures 2024-04-16 Piperazine Citrate
US $0.00 / kg 1kg 99% 10000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
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