6-Bromo-2-naphthoic acid
- CAS No.
- 5773-80-8
- Chemical Name:
- 6-Bromo-2-naphthoic acid
- Synonyms
- RAVI-001;6-Bromo-2-naphthoic;6-BROMO-2-NAPHTHALENE;6-Bromo-2-phthoic acid;6-BROMO-2-NAPHTHOIC ACID;6-BROMO-2-NAPHTHIOC ACID;6-BROMO-2-NAPHTHOLIC AICD;6-BROMO-2-NAPHTHOLIC ACID;6-Bromo-2-naphthoicacid,96%;6-BROMO-2-NAPHTHOIC ACID 99%
- CBNumber:
- CB2467951
- Molecular Formula:
- C11H7BrO2
- Molecular Weight:
- 251.08
- MDL Number:
- MFCD01075720
- MOL File:
- 5773-80-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 294-295°C |
|---|---|
| Boiling point | 387.3±17.0 °C(Predicted) |
| Density | 1.648±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | powder to crystal |
| pka | 4.06±0.30(Predicted) |
| color | White to Light yellow |
| Water Solubility | Insoluble in water. |
| BRN | 2328940 |
| InChI | InChI=1S/C11H7BrO2/c12-10-4-3-7-5-9(11(13)14)2-1-8(7)6-10/h1-6H,(H,13,14) |
| InChIKey | NPMCAVBMOTZUPD-UHFFFAOYSA-N |
| SMILES | C1=C2C(C=C(Br)C=C2)=CC=C1C(O)=O |
| CAS DataBase Reference | 5773-80-8(CAS DataBase Reference) |
| UNSPSC Code | 12352106 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H335-H315-H319 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36/37/39-36 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HS Code | 2916399090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
6-Bromo-2-naphthoic acid price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | CDS004635 | 6-Bromo-2-naphthoic acid AldrichCPR | 100 mg | $77.9 | 2026-04-30 | Buy | |
| TCI Chemical | B3823 | 6-Bromo-2-naphthoic Acid >98.0%(GC)(T) | 5773-80-8 | 5g | $56 | 2026-04-30 | Buy |
| TCI Chemical | B3823 | 6-Bromo-2-naphthoic Acid >98.0%(GC)(T) | 5773-80-8 | 25g | $220 | 2026-04-30 | Buy |
| Usbiological | 262018 | 6-Bromo-2-naphtholic acid Asreported | 5773-80-8 | 50g | $545 | 2026-06-03 | Buy |
| Usbiological | 262018 | 6-Bromo-2-naphtholic acid Asreported | 5773-80-8 | 100g | $746 | 2026-06-03 | Buy |
6-Bromo-2-naphthoic acid Chemical Properties, Uses, Production
Chemical Properties
Pale brown solid
Uses
Benzimidazole derivatives has been prepared by using ortho-phenyl diamine and 6-bromo-2-naphthoic acid.
Synthesis
33626-98-1
5773-80-8
Methyl 6-bromo-2-naphthalenecarboxylate (3b) (2.7 g, 10.0 mmol) was used as a raw material to form a suspension with potassium hydroxide (1.1 g, 20.0 mmol) in methanol (50 mL) at 50 °C with vigorous stirring. At the beginning of the reaction, the suspension gradually changed to a homogeneous solution, indicating that the raw material was completely consumed. After the reaction lasted for 8 hours, about 2/3 of the volume of solvent was removed by evaporation under reduced pressure. Subsequently, water (1500 mL) was added to the residue and the unreacted esters were extracted with ethyl acetate. The aqueous phase was acidified to pH 3 with 10% H2SO4 and subsequently extracted with ethyl acetate (3 x 200 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give pure 6-bromo-2-naphthalenecarboxylic acid (3a) (2.1 g, 8.4 mmol, 84% yield). The melting point of the product was 290-294 °C (decomposition). High resolution mass spectrum (ESI+): m/z [M + 1]+ calculated value (C11H8BrO2) was 252.08591, measured value was 252.08582. 1H NMR (DMSO-d6) δ= 7.72 (1H, dd, J = 8.5 and 1.8 Hz, 7-naphthalenyl H), 7.99 (1H, d, J = 8.6 Hz, 4-naphthalenyl H) ), 8.02 (1H, dd, J = 8.6 and 1.4 Hz, 8-naphthalenyl H), 8.09 (1H, d, J = 8.8 Hz, 3-naphthalenyl H), 8.30 (1H, d, J = 1.6 Hz, 5-naphthalenyl H), 8.62 (1H, s, 1-naphthalenyl H), and 13.15 (1H, br.s, COOH).13C NMR ( 125.76 MHz, DMSO-d6) δ= 121.93, 126.50, 127.61, 128.81, 129.83, 130.01, 130.64, 130.90, 131.63, 136.11, 167.30.
References
[1] Organic and Biomolecular Chemistry, 2015, vol. 13, # 27, p. 7477 - 7486
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 4, p. 1557 - 1568
[3] Bioorganic Chemistry, 2011, vol. 39, # 4, p. 151 - 158
[4] Patent: US2012/88746, 2012, A1. Location in patent: Page/Page column 47-48
6-Bromo-2-naphthoic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Xingshun New Material Co., Ltd. | 0519-86464994 13382824994 | gxy@xingshengtech.com | China | 100 | 65 |
| Wuhan Yuqing Jiaheng Pharmaceutical Co., Ltd | 027-83850128 18207128853 | 3860188266@qq.com | China | 997 | 58 |
| Nanjing Henghua Pharmaceutical Technology Co., Ltd | 15862800858 | 173990752@qq.com | China | 25 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 18918157536; | sales8178@energy-chemical.com | China | 45000 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Latest Price from 6-Bromo-2-naphthoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-10-16 | 6-Bromo-2-naphthoic acid
5773-80-8
|
10KG | 98%min | 500kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-08-25 | 6-Bromo-2-naphthoic acid
5773-80-8
|
$2.00-5.00 | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |||
 |
2025-04-04 | 6-Bromo-2-naphthoic acid
5773-80-8
|
1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd.
|
-
- 6-Bromo-2-naphthoic acid
5773-80-8
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 6-Bromo-2-naphthoic acid
5773-80-8
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- 6-Bromo-2-naphthoic acid
5773-80-8
- 98%
- Henan Aochuang Chemical Co.,Ltd.
