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ZM 449829

ZM 449829 structure

CAS No.: 4452-06-6

Chemical Name:: ZM 449829

Synonyms: ZM 449829;JAK3 INHIBITOR V;2'-Acrylonaphthone;naphthyl vinyl ketone;2-NAPHTHYLVINYL KETONE;1-Naphthalen-2-yl-propenone;1-(2-Naphthyl)-2-propen-1-one;1-(2-NAPHTHALENYL)-2-PROPEN-1-ONE;1-(Naphthalen-2-yl)prop-2-en-1-one;2-Propen-1-one, 1-(2-naphthalenyl)-

CBNumber:: CB2716532

Molecular Formula:: C13H10O

Molecular Weight:: 182.22

MDL Number:: MFCD04974535

MOL File:: 4452-06-6.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:16

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ZM 449829 Properties

Boiling point	319.3±15.0 °C(Predicted)
Density	1.093±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form	White waxy solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06,GHS08
Signal word	Danger
Hazard statements	H301-H311-H331-H341
Precautionary statements	P201-P202-P261-P264-P270-P271-P280-P302+P352-P304+P340-P308+P313-P310-P330-P361-P403+P233-P405-P501

ZM 449829 price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	420122	JAK3 Inhibitor V - CAS 932258 - Calbiochem The JAK3 Inhibitor V, also referenced under CAS 932258, controls the biological activity of JAK3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.	4452-06-6	10mg	$308	2023-01-07	Buy
Tocris	1366	ZM449829 ≥98%(HPLC)	4452-06-6	10	$164	2021-12-16	Buy
Tocris	1366	ZM449829 ≥98%(HPLC)	4452-06-6	50	$651	2021-12-16	Buy
TRC	Z487008	ZM449829	4452-06-6	50mg	$620	2021-12-16	Buy
TRC	Z487008	ZM449829	4452-06-6	10mg	$145	2021-12-16	Buy

Product number	Packaging	Price	Buy
420122	10mg	$308	Buy
1366	10	$164	Buy
1366	50	$651	Buy
Z487008	50mg	$620	Buy
Z487008	10mg	$145	Buy

ZM 449829 Chemical Properties,Uses,Production

Uses

ZM 449829, is a potent, selective inhibitor of JAK3 (Janus tyrosine kinase 3) which binds competitively to the JAK3 ATP site. Also inhibits STAT-5 phosphorylation and T-cell proliferation.

Definition

ChEBI: 1-(2-naphthalenyl)-2-propen-1-one is a member of naphthalenes.

ZM 449829 synthesis

Synthesis of ZM 449829 from Formaldehyde and 2-Acetonaphthone

ZM 449829 Preparation Products And Raw materials

Raw materials

1-Propanone, 3-chloro-1-(2-naphthalenyl)- 2-Naphthalenemethanol, α-ethenyl- N-methoxy-N-methylnaphthalene-2-carboxamide 4,4,4-TRIFLUORO-1-(2-NAPHTHYL)-1,3-BUTANEDIONE 4-(2-NAPHTHYL)-4-OXOBUTANOICACID

2-Naphthoyl chloride Methanol Dimethyl sulfoxide 2-Acetonaphthone Formaldehyde

2-Naphthaldehyde N,N-Dimethylacetamide Vinylmagnesium bromide

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Preparation Products

ZM 449829 Suppliers

Global( 54)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
ChemeGen 中国	18818260767	sales@chemegen.com	China	6975	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
BeiJing Hwrk Chemicals Limted	0757-86329057 18934348241	sales4.gd@hwrkchemical.com	China	14067	55
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Shanghai Jian Chao Chemical Technology Co., Ltd.	18017383231 18017383231	lyh_antaeus@163.com	China	9352	55
Synchem OHG	+49 5662 408730	info@synchem.de	Germany	4708	70

Supplier	Advantage
TargetMol Chemicals Inc.	58
LEAPCHEM CO., LTD.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
ChemeGen 中国	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
BeiJing Hwrk Chemicals Limted	55
VDM Biochemicals	64
Shanghai Jian Chao Chemical Technology Co., Ltd.	55
Synchem OHG	70

ZM 449829 Spectrum

ZM 449829(4452-06-6)¹HNMR

4452-06-6(ZM 449829)Related Search:

α-Naphthoflavone 1,4-CHRYSENEQUINONE 3-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-PROP-2-EN-1-ONE 1,4-ANTHRAQUINONE 1-(2-NAPHTHYL)-3-(2-THIENYL)-2-PROPEN-1-ONE

A-NAPHTHOFLAVONOL 4'-HYDROXY-ALPHA-NAPHTHOFLAVONE 3-(1,3-BENZODIOXOL-5-YL)-1-(2-NAPHTHYL)PROP-2-EN-1-ONE (E)-3-(2-FURYL)-1-(2-NAPHTHYL)-2-PROPEN-1-ONE 2'-METHOXY-7,8-BENZOFLAVONE

4'-METHOXY-ALPHA-NAPHTHOFLAVONE ETHYL 2-(2,6-DIBROMO-4-[3-(2-NAPHTHYL)-3-OXOPROP-1-ENYL]PHENOXY)ACETATE 1-(2-NAPHTHYL)-3-(3,4,5-TRIMETHOXYPHENYL)PROP-2-EN-1-ONE 3',4'-DIMETHOXY-ALPHA-NAPHTHOFLAVONE 4-[(E)-3-(2-naphthyl)-3-oxo-1-propenyl]phenyl 2-thiophenecarboxylate

3-(2-CHLOROPHENYL)-1-(2-NAPHTHYL)PROP-2-EN-1-ONE 3',4'-DIHYDROXY-ALPHA-NAPHTHOFLAVONE 3-(4-ISOPROPYLPHENYL)-1-(2-NAPHTHYL)PROP-2-EN-1-ONE

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2-NAPHTHYLVINYL KETONE 1-(2-NAPHTHALENYL)-2-PROPEN-1-ONE JAK3 INHIBITOR V 2-Propen-1-one, 1-(2-naphthalenyl)- 1-Naphthalen-2-yl-propenone 1-(2-Naphthyl)-2-propen-1-one 2'-Acrylonaphthone ZM 449829 JAK3 Inhibitor V - CAS 932258 - Calbiochem 1-(Naphthalen-2-yl)prop-2-en-1-one naphthyl vinyl ketone 4452-06-6 4452-6-6 Intracellular Signaling