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Octopamine

CAS No.
104-14-3
Chemical Name:
Octopamine
Synonyms
p-Octopamine;Norden;OctopaMine-d3;ND-50;ND 50;C04227;Analet;Norfen;Norphen;OCTOPAMINE
CBNumber:
CB8482020
Molecular Formula:
C8H11NO2
Molecular Weight:
153.18
MDL Number:
MFCD00044589
MOL File:
104-14-3.mol
MSDS File:
SDS
Last updated:2023-09-11 17:45:53

Octopamine Properties

Melting point 157-158 °C
Boiling point 276.1°C (rough estimate)
Density 1.1577 (rough estimate)
refractive index 1.5010 (estimate)
pka pKa 8.88 (Uncertain);9.53 (Uncertain)
CAS DataBase Reference 104-14-3(CAS DataBase Reference)
EWG's Food Scores 1-3
FDA UNII 14O50WS8JD
ATC code C01CA18

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312
Precautionary statements  P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501
RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 oral in rat: 1240mg/kg

Octopamine price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 461480 Octopamine 104-14-3 250mg $496 2021-12-16 Buy
American Custom Chemicals Corporation API0008679 DL-OCTOPAMINE 95.00% 104-14-3 0.5G $271 2021-12-16 Buy
AHH MT-39562 4-(2-Amino-1-hydroxy-ethyl)phenol 98% 104-14-3 1000g $680 2021-12-16 Buy
Product number Packaging Price Buy
461480 250mg $496 Buy
API0008679 0.5G $271 Buy
MT-39562 1000g $680 Buy

Octopamine Chemical Properties,Uses,Production

Description

An alkaloid found in annual rye grass, this base has been suggested as a possible precursor of annuloline (q.v.).

Originator

Norfen,Morishita, Japan ,1975

Uses

Octopamine is a biogenic monoamine structurally related to Noradrenaline (N661038), it acts as a neurohormone, neuromodulator and a neurotransmitter in invertebrates.

Definition

ChEBI: Octopamine is a member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates. It has a role as a neurotransmitter. It is a member of phenylethanolamines and a member of tyramines. It is a conjugate base of an octopaminium.

Manufacturing Process

A solution of 33 grams of anhydrous aluminum chloride in 60 grams of nitrobenzene, to which a mixture of 14 grams of phenol and 9.3 grams of hydrochloride of amino-acetonitrile was added, had dry hydrochloric acid gas introduced into it for 3 hours, while stirring and cooling to keep the temperature between 20° and 30°C. The reaction mixture was then poured, with cooling, into 70 cc of water and the deposit obtained was sucked off, washed with acetone and dissolved in 300 cc of water. The solution thus prepared was decolorized with carbon, 50 grams of 30% sodium citrate solution was added to it, and then it was made slightly alkaline with ammonia. Thereupon hydroxy-4'-phenyl-1-amino-2-ethanone crystallized out in the form of leaflets. The yield was 7.7 grams.
The hydrochloride of this base, obtained by evaporation to dryness of a solution of the base in dilute hydrochloric acid and subsequent treatment of the residue with ethyl alcohol and acetone, had a chlorine content of 18.84%, (calculated, 18.90%).
This hydrochloride, on being dissolved in water and hydrogenated with hydrogen and a nickel catalyst, gave a good yield of hydrochloride of hydroxy4'-phenyl-1-amino-2-ethanol melting, after crystallization from a mixture of ethyl alcohol and butanone-2, at from 177° to 179°C with decomposition

Therapeutic Function

Hypertensive

References

Hardwick, Axelrod, Plant Physiol., 44, 1745 (1969)

121778-81-2
104-14-3
Synthesis of Octopamine from 2-Oxazolidinone, 5-(4-methoxyphenyl)-

Octopamine Preparation Products And Raw materials

Octopamine Suppliers

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Zhejiang ZETian Fine Chemicals Co. LTD
18957127338 stella@zetchem.com China 2141 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9991 58
Wuhan Han Sheng New Material Technology Co.,Ltd
+8617798174412 admin01@hsnm.com.cn China 2118 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Shandong Hanjiang Chemical Co., Ltd
+86-0533-2066820 +8618369939125 hanson@sdhanjiang.com China 1527 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32360 55

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View Lastest Price from Octopamine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Octopamine pictures 2023-09-11 Octopamine
104-14-3
US $100.00 / bag 1bag 99 5000 Hebei Fengqiang Trading Co., LTD
Octopamine pictures 2023-06-10 Octopamine
104-14-3
US $150.00 / kg 1kg 99.9% 10000MT Henan Bao Enluo International TradeCo.,LTD
Octopamine pictures 2020-02-12 Octopamine
104-14-3
US $7.00 / KG 1KG 99% 100KG Career Henan Chemical Co
  • Octopamine pictures
  • Octopamine
    104-14-3
  • US $100.00 / bag
  • 99
  • Hebei Fengqiang Trading Co., LTD
  • Octopamine pictures
  • Octopamine
    104-14-3
  • US $150.00 / kg
  • 99.9%
  • Henan Bao Enluo International TradeCo.,LTD
  • Octopamine pictures
  • Octopamine
    104-14-3
  • US $7.00 / KG
  • 99%
  • Career Henan Chemical Co
4-(2-AMINO-1-HYDROXY-ETHYL)-PHENOL ALPHA-(AMINOMETHYL)-PARA-HYDROXYBENZYLALCOHOL PARA-OCTOPAMINE D-(-)-octopamine ND 50 ND-50 α-(Aminomethyl)-p-hydroxybenzyl alcohol C04227 p-Hydroxyphenylethanolamine RARECHEM AL BW 0555 OCTOPAMINE AURORA KA-7795 1-(4-HYDROXYPHENYL)-2-AMINOETHANOL Etilefrine Impurity 9 Benzenemethanol, α-(aminomethyl)-4-hydroxy- Octopamine Impurity 3 Octopamine DISCONTINUED. Please see O239750. Octapamine Analet Norfen Norphen Norsympathol p-Octopamine OctopaMine-d3 Norden 104-14-3 C9H10NO2D3