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DIHYDRORHODAMINE 123

DIHYDRORHODAMINE 123 structure

CAS No.: 109244-58-8

Chemical Name:: DIHYDRORHODAMINE 123

Synonyms: DHR;D 632;DHR123;D 23806;Dihydrorhodamine;DIHYDRORHODAMINE 123;Dihydrohodamine 123;Dihydrorhodamine123(DHR123);Dihydrorhodamine 123 *CAS 109244-58-8*;DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE

CBNumber:: CB3320004

Molecular Formula:: C21H18N2O3

Molecular Weight:: 346.38

MDL Number:: MFCD04221428

MOL File:: 109244-58-8.mol

MSDS File:: SDS

Last updated:2023-09-20 16:43:00

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DIHYDRORHODAMINE 123 Properties

Melting point	163–165℃
Boiling point	526.9±50.0 °C(Predicted)
Density	1.313±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMSO: >5mg/mL
form	powder
pka	4.70 ± 0.40, most basic, temperature: 25 °C
color	Light red or pinkish-white
λmax	289 nm
BRN	5989965
Biological Applications	Generating,detecting & measuring reactive oxygen species; generating,detecting & measuring reactive nitrogen species; detecting phosphates,peroxynitrile; measuring respiratory burst; chronic granulomatous disease DHR assay; screening

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H302-H315-H335
Precautionary statements	P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Safety Statements	22-24/25
WGK Germany	3
F	10-23

DIHYDRORHODAMINE 123 price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	D1054	Dihydrorhodamine 123 ≥95%	109244-58-8	2mg	$131	2024-03-01	Buy
Sigma-Aldrich	D1054	Dihydrorhodamine 123 ≥95%	109244-58-8	10mg	$415	2024-03-01	Buy
Cayman Chemical	85100	Dihydrorhodamine 123 ≥98%	109244-58-8	1mg	$37	2024-03-01	Buy
Cayman Chemical	85100	Dihydrorhodamine 123 ≥98%	109244-58-8	5mg	$98	2024-03-01	Buy
Sigma-Aldrich	309825	Dihydrorhodamine 123 - CAS 109244-58-8 - Calbiochem	109244-58-8	5mg	$461	2024-03-01	Buy

Product number	Packaging	Price	Buy
D1054	2mg	$131	Buy
D1054	10mg	$415	Buy
85100	1mg	$37	Buy
85100	5mg	$98	Buy
309825	5mg	$461	Buy

DIHYDRORHODAMINE 123 Chemical Properties,Uses,Production

Description

DHR is a cell-permeable fluorogenic probe that is used as an indicator of intracellular peroxynitrite formation. It is oxidized by peroxynitrite to the highly fluorescent product rhodamine in vitro. Neither nitric oxide, superoxide, nor hydrogen peroxide alone appear to oxidize DHR. Formation of rhodamine can be monitored by fluorescence spectroscopy using excitation and emission wavelengths of 500 and 536 nm, respectively, or by absorbance spectroscopy at 500 nm (ε = 78,800 M⁻¹cm⁻¹). DHR has been used to investigate reactive oxygen intermediates produced by endothelial cells, eosinophils, and reactive microglia.

Uses

Dihydrorhodamine 123 (DHR) has been used for the detection of free intracellular radicals or ROS (reactive oxygen species) in head kidney-derived macrophages. It has also been used in DHR assay in red blood cells and in oxidative burst assay in neutrophils.

Uses

Dihydrorhodamine 123 is the uncharged and nonfluorescent reduction product of the mitochondrion-selective dye rhodamine 123 used for investigation of reacitve oxygen intermediates.

General Description

Cell-permeable fluorogenic probe that is useful for the detection of reactive oxygen species (ROS) such as peroxide and peroxynitrite. Dihydrorhodamine is not fluorescent unless it is converted to rhodamine 123.

Biochem/physiol Actions

Cell permeable: yes

DIHYDRORHODAMINE 123 Preparation Products And Raw materials

Raw materials

Preparation Products

DIHYDRORHODAMINE 123 Suppliers

Global( 111)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	product@acmec-e.com	China	33349	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Nantong Hi-Future Biotechnology Co., Ltd	18051384581	sales@chemhifuture.com	China	2996	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Beijing Ouhe Technology Co., Ltd	010-82967028 13552068683	2355560935@qq.com	China	12426	60
Syntechem Co.,Ltd		info@syntechem.com	China	12990	57

Supplier	Advantage
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
Alfa Chemistry	58
Nantong HI-FUTURE Biology Co., Ltd.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
Nantong Hi-Future Biotechnology Co., Ltd	58
J & K SCIENTIFIC LTD.	76
Beijing Ouhe Technology Co., Ltd	60
Syntechem Co.,Ltd	57

DIHYDRORHODAMINE 123 Spectrum

DIHYDRORHODAMINE 123(109244-58-8)¹HNMR

109244-58-8(DIHYDRORHODAMINE 123)Related Search:

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DIHYDRORHODAMINE 123 DHR DHR123 2-(3,6-DIAMINO-9H-XANTHEN-9-YL)-BENZOIC ACID, METHYL ESTER Dihydrohodamine 123 Dihydrorhodamine DIHYDRORHODAMINE 123, FOR FLUOR-ESCENCE Dihydrorhodamine123(DHR123) Benzoic acid, 2-(3,6-diamino-9H-xanthen-9-yl)-, methyl ester Methyl 2-(3,6-diamino-9H-xanthen-9-yl)benzoate D 23806 D 632 Dihydrorhodamine 123 - CAS 109244-58-8 - Calbiochem Dihydrorhodamine 123 *CAS 109244-58-8* 109244-58-8 BioChemical Biochemicals and Reagents Fluorescent Enzyme Substrates Fluorescent Probes, Labels, Particles and Stains Alphabetical Xanthene AlphabeticalStains and Dyes DFluorescent Probes, Labels, Particles and Stains Fluorescent Enzyme Substrates Fluorescent Enzyme Substrates for Flow Cytometry Fluorescent Probes, Labels, Particles and Stains Stains&Dyes, A to