| Identification | More | [Name]
Formamidine acetate | [CAS]
3473-63-0 | [Synonyms]
FAA
FORMAMIDINE ACETATE
FORMAMIDINE ACETATE SALT
FORMAMIDINE,ACETIC ACID
FORMAMIDINE ACETIC ACID SALT
IMINOFORMAMIDE ACETATE
Methanimidamideacetate
Formamidinium acetate
formamidine monoacetate
Formamidineacetate,99%
Formamidinmonoacetat
Methanimidamide monoacetate
Acetic acid·formamidine | [EINECS(EC#)]
222-442-5 | [Molecular Formula]
C3H8N2O2 | [MDL Number]
MFCD00012866 | [Molecular Weight]
104.11 | [MOL File]
3473-63-0.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow crystalline powder | [Melting point ]
158-161 °C (dec.)(lit.)
| [density ]
1.124 | [storage temp. ]
Store below +30°C. | [solubility ]
832g/l | [form ]
Liquid | [color ]
Clear colorless to light yellow | [PH]
8 (400g/l, H2O, 20℃) | [Water Solubility ]
832 g/L (21 ºC) | [Sensitive ]
Hygroscopic | [BRN ]
3563488 | [InChIKey]
XPOLVIIHTDKJRY-UHFFFAOYSA-N | [CAS DataBase Reference]
3473-63-0(CAS DataBase Reference) | [EPA Substance Registry System]
3473-63-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R43:May cause sensitization by skin contact.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36/37:Wear suitable protective clothing and gloves .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S27:Take off immediately all contaminated clothing . | [WGK Germany ]
2
| [F ]
3-9-21 | [Autoignition Temperature]
565 °C | [TSCA ]
Yes | [HS Code ]
29252000 | [Toxicity]
LD50 orally in Rabbit: 2510 mg/kg LD50 dermal Rat > 2000 mg/kg |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow crystalline powder | [Uses]
Formamidine acetate is used as an intermediate in the synthesis of active pharmaceutical ingredients. It is also used as a condensing agent for the preparation of pyrimidine and imidazole heterocycles. | [Purification Methods]
Unlike the hydrochloride, the acetate salt is not hygroscopic. It is recrystallised from a small volume of acetic acid, by addition of EtOH and the crystals are washed with EtOH then Et2O and dried in a vacuum. [Taylor et al. Org Synth 46 39 1966, Beilstein 2 IV 82.] |
|
|