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Phenol Red

CAS No.
143-74-8
Chemical Name:
Phenol Red
Synonyms
PR;PHENOLSULFONPHTHALEIN;phenolsulphonphthalein;A-HYDROXY-A A-BIS(P-HYDROXYPHENYL)-O-TOLUENESULFONIC ACID G-SULTONE;PRGR;NR3C3;P3532-5G;Phenolrde;Phenol re;PHENOL RED
CBNumber:
CB3780134
Molecular Formula:
C19H14O5S
Molecular Weight:
354.38
MDL Number:
MFCD00003552
MOL File:
143-74-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-20 18:12:28

Phenol Red Properties

Melting point >300 °C
Boiling point >300°C
bulk density 200-300kg/m3
Density 1.445 Mg m-3
refractive index 1.5300 (estimate)
Flash point >300°C
storage temp. no restrictions.
solubility 1 M NaOH: soluble1mg/mL
form Solid
pka 7.9(at 25℃)
color Red
PH Range 6.6(YELLOW)-8.0(RED)
Odor Odorless
PH 6.8~8.4
Water Solubility 0.77 g/L
λmax 557nm, 558nm, 360nm, 423nm, 433nm
ε(extinction coefficient) ≥10000 at 288-294nm in H2O
≥55000 at 555-561nm in H2O
≥7000 at 357-363nm in H2O
Merck 14,7247
BRN 326470
Major Application Display device, sol-gel matrix, photoreceptors, fuel cells, waveguides, paints, detergents, cosmetics, antiperspirant composition, diapers, screening bacteria, detecting viable cells, diagnosis of urogenital ureaplasmosis, treatment of pathogen infections, amyloid-associated diseases, glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud’s syndrome, heparin overdose, vulvodynia, wound healing, psychoactive drugs, evaluating dental caries activity
Cosmetics Ingredients Functions BUFFERING
InChI 1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H
InChIKey BELBBZDIHDAJOR-UHFFFAOYSA-N
LogP 3.020
CAS DataBase Reference 143-74-8(CAS DataBase Reference)
EWG's Food Scores 1
NCI Dictionary of Cancer Terms PR
FDA UNII I6G9Y0J1OJ
EPA Substance Registry System Phenol Red (143-74-8)
UNSPSC Code 12352207
NACRES NA.75

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340+P312
target organs Respiratory system
Hazard Codes  Xi,C
Risk Statements  36/37/38-34
Safety Statements  37/39-26-45-36/37/39-27
WGK Germany  3
RTECS  SJ7490000
TSCA  TSCA listed
HS Code  29349990
Storage Class 11 - Combustible Solids
Hazard Classifications Skin Irrit. 2
STOT SE 3
Toxicity LD50 orl-rat: >600 mg/kg CTOXAO 4(2),185,71
NFPA 704
0
1 0

Phenol Red price More Price(94)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 114529 Phenol Red ACS reagent 143-74-8 5g $31.8 2026-04-30 Buy
Sigma-Aldrich 114529 Phenol Red ACS reagent 143-74-8 25g $92.2 2026-04-30 Buy
Sigma-Aldrich 1.59375 Phenol red (phenolsulfonphthalein) Reag. Ph Eur 143-74-8 1g $906 2026-04-30 Buy
Sigma-Aldrich 1.07241 Phenol red indicator ACS 143-74-8 5G $129 2026-04-30 Buy
Sigma-Aldrich 1.59375 Phenol red (phenolsulfonphthalein) Reag. Ph Eur 143-74-8 100g $9060 2026-04-30 Buy
Product number Packaging Price Buy
114529 5g $31.8 Buy
114529 25g $92.2 Buy
1.59375 1g $906 Buy
1.07241 5G $129 Buy
1.59375 100g $9060 Buy

Phenol Red Chemical Properties, Uses, Production

Description

Phenol red belongs to the class of triphenylmethane dyes and is widely used in the textile industry.

Chemical Properties

dark red powder

Uses

As indicator in 0.02-0.05% alcohol solution. pH 6.8 yellow, 8.4 red.

Uses

Phenol red is used as a non absorbed marker in gravimetric method. It is a pH indicator used in cell biology laboratories and in home swimming pool test kits. It is used to check the kidney function based on the excreted phenol red by colorimetric method.

Uses

Phenol red solution acts as a pH indicator for the culture medium.

Definition

ChEBI: 3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.

Application

Phenol red solution has been used:
As a tracer dye for microinjection of zebrafish eggs.
As a component of the mMW medium for preparation of mouse embryos.
In the preparation of versene-ethylenediamine tetraacetic acid (EDTA) solution.

Preparation

Phenol red is prepared in Dulbecco′s Phosphate Buffered Saline.

Biochem/physiol Actions

Phenol Red is a pH indicator which changes color from yellow to red.

Safety Profile

Moderately toxic by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxicvapors of SOx.

Enzyme inhibitor

This pH-indicating dye (FW = 354.38 g/mol; CAS 143-74-8; pKa = 7.9; yellow < pH 6.8; red > pH 8.4), also known as phenolsulfonphthalein and sulfophthalein, is a diagnostic aid for evaluating renal function. A typical stock indicator solution is 0.1 g phenol red in 28.2 mL 10 mM NaOH and 221.8 mL water. Target(s): aldehyde reductase; glutaminase; gglutamyl transpeptidase; glutathione S-transferase; 4- methyleneglutaminase; phosphate uptake; thromboxane A2/prostaglandin H2 receptor; and thyroglobulin iodination.

81-08-3
108-95-2
143-74-8
Synthesis of Phenol Red from 2-Sulfobenzoic anhydride and Phenol

Phenol Red Preparation Products And Raw materials

Global Suppliers ( 623)
Supplier Tel Email Country ProdList Advantage
Kaiyuan city Shenxin fine chemical co., ltd. 024-22595298 18698863499 1253960@qq.com China 165 58
Shenyang Shengyuan chemical industry co., ltd 13190211560 1319074246@qq.com China 95 58
Shenyang Delier Biotechnology Co., Ltd. 15942301471 15942301471 15942301471@163.cn China 114 58
Anhui kuer Bioengineering Co., Ltd 0551-65171243 13856024262 kuer@kuerhuaxue.com China 2996 55
henyang Zhuohua Biotechnology Co., Ltd. 13940293610 13940293610 332189598@qq.com China 96 58
Shenyang Snota Biotech Co.,Ltd +86-024-31174117 18002429090 2193387905@qq.com China 104 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84

Related Questions

Ask a question
Q:How to prepare a phenol red (phenolsulphonphthalein) indicator solution?STAR - Jul 2,2026
A:Dissolve 0.1 g of phenol red in 100 mL of ethanol and sodium hydroxide solution, dilute to 0.1 mol/L, and make up to 100 mL with water. This acid-base indicator changes colour from brownish-orange to yellow in the pH range of 1.2 ~ 3.0; in the pH range of 6.5 ~ 8.0, it changes colour from brownish-yellow to red-violet.

View Latest Price from Phenol Red manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
phenol red pictures 2026-10-10 phenol red
143-74-8
$100.00 1KG 99% 1000 KG HANGZHOU DINGYAN CHEM CO.,LTD
Phenol Red pictures 2026-09-02 Phenol Red
143-74-8
$2.00-5.00 1kg 99% Henan Fengda Chemical Co., Ltd
Phenol Red pictures 2026-08-29 Phenol Red
143-74-8
$29.00 99.95% 10g TargetMol Chemicals Inc.
  • phenol red pictures
  • phenol red
    143-74-8
  • $100.00
  • 99%
  • HANGZHOU DINGYAN CHEM CO.,LTD
  • Phenol Red pictures
  • Phenol Red
    143-74-8
  • $2.00-5.00
  • 99%
  • Henan Fengda Chemical Co., Ltd
  • Phenol Red pictures
  • Phenol Red
    143-74-8
  • $29.00
  • 99.95%
  • TargetMol Chemicals Inc.
PHENOL REDRESEARCH GRADE 3,3-BIS(P-HYDROXYPHENYL)-2,1-3H-BENZOXATHIOLE SULFONAPHTHAL TIMTEC-BB SBB006473 PHENOSULFOHEPHTHALEIN INDICATOR PHENOLSULFONEPHTHALEIN PHENOLSULFONPHTHALEIN TEST SOLUTION PHENOLSULPHONEPHTHALEIN PHENYLSULFONEPHTHALEIN PHENYLSULFONPHTHALEIN PHENOL RED LABOTEST-BB LT00455865 PHENOL RED FREE ACID CELL CULTURE TESTED 4-[3-(4-Hydroxyphenyl)-1,1-dioxobenzo[c]oxathiol-3-yl]phenol 3,3-Bis(4-hydroxyphenyl)-3H-2,1-benzoxathiol 1,1-dioxide Phenol Red,pure,indicator Phenol Red,pure,conform to ACS 4,4’-(3h-2,1-benzoxathiol-3-ylidene)bisphenol,s,s-dioxide 4,4’-(3h-2,1-benzoxathiol-3-ylidene)diphenol,s,s-dioxide abcolphenolredf/a fenolipuna Phenol,4,4’-(3H-2,1-benzoxathiol-3-ylidene)bis-,S,S-dioxide phenol,4,4’-(3h-2,1-benzoxathiol-3-ylidene)di-,s,s-dioxide Phenolrde psp(indicator) Sulfonphthal sulphental sulphonphthal sulphonthal Phenol Red, indicator, pure 25GR Phenol red, indicator, ACS Phenol red, solution 0,02%, ACS Phenolsulfonphthalein (100 mg) Phenol Red p.a. PHENOL RED INDICATOR PH 6,4 - 8,2 ACS PHENOL RED (PHENOLSULFONPHTHALEIN) REAG. Phenol Red TS, (U.S.P. Test Solution) Phenol red,ACS Grade NR3C3 nuclear receptor 3C3 PRGR Phenol red (phenolsulfonphthalein) Reag. Ph Eur. Phenol Red, Pure 3,3-bis(p-Hydroxyphenyl)-3H-2,1-benzoxathiol-1,1-dioxide Phenol re 3,3-bis(4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide Phenol Red Solution 0.5% 2,4,6-Trimethylheptan-4-ol PHENOL RED FREE ACID PHENOL RED INDICATOR, REAG. ACS PHENOL RED 0.5% SOLUTION IN DULBECCO'S*P HOSPHATE BU PHENOL RED CONCENTRATE (2000X)*ELECTROPH ORESIS GRAD PhenolRedIndicatorGr PhenolRedIndicatorSolution PHENOL RED GR ( pH INDICATOR) Phenol Red, conform to ACS, pure Phenol Red, indicator, pure Phenol, 4,4-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-