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N-Heptafluorobutyrylimidazole

CAS No.
32477-35-3
Chemical Name:
N-Heptafluorobutyrylimidazole
Synonyms
HEPTAFLUOROBUTYRYLIMIDAZOLE;HFBI;NSC 151966;1-(HeptafL;uorobutyryL;Heptafluorobutyric iMidazole;N-HEPTAFLUOROBUTYRYLIMIDAZOLE;1-(PERFLUOROBUTYRYL)IMIDAZOLE;N-(Perfluorobutyryl)imidazole;N-HEPTAFLUOROBUTANOYLIMIDAZOLE
CBNumber:
CB4100522
Molecular Formula:
C7H3F7N2O
Molecular Weight:
264.1
MDL Number:
MFCD00014503
MOL File:
32477-35-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:18:33

N-Heptafluorobutyrylimidazole Properties

Melting point 9-13 °C
Boiling point 161 °C(lit.)
Density 1.490 g/mL at 25 °C(lit.)
refractive index n20/D 1.3865(lit.)
Flash point 171 °F
storage temp. 2-8°C
solubility Miscible with chloroform and methanol.
form Oil
pka 1.37±0.10(Predicted)
color Pale Yellow
Sensitive Hygroscopic
BRN 4488026
Stability Moisture Sensitive
InChI 1S/C7H3F7N2O/c8-5(9,6(10,11)7(12,13)14)4(17)16-2-1-15-3-16/h1-3H
InChIKey MSYHGYDAVLDKCE-UHFFFAOYSA-N
SMILES FC(F)(F)C(F)(F)C(F)(F)C(=O)n1ccnc1
CAS DataBase Reference 32477-35-3(CAS DataBase Reference)
NIST Chemistry Reference N-Heptafluorobutyrylimidazole(32477-35-3)
EPA Substance Registry System 1-(Heptafluorobutyryl)imidazole (32477-35-3)
UNSPSC Code 12352005
NACRES NA.32

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a-P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P403+P235-P501
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36/37/39-24/25
RIDADR  NA 1993 / PGIII
WGK Germany  3
F  3-10-21
Hazard Note  Irritant/Hygroscopic/Keep Cold
HazardClass  IRRITANT, MOISTURE SENSITIVE, KEEP COLD
HS Code  29332900
Storage Class 10 - Combustible liquids
NFPA 704
2
2 0

N-Heptafluorobutyrylimidazole price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 74382 N-Heptafluorobutyrylimidazole for GC derivatization, ≥98.5% (GC) 32477-35-3 1ml $115 2026-04-30 Buy
Sigma-Aldrich 74382 N-Heptafluorobutyrylimidazole for GC derivatization, ≥98.5% (GC) 32477-35-3 10x1ml $739 2026-04-30 Buy
Sigma-Aldrich 556645 N-Heptafluorobutyrylimidazole 97% 32477-35-3 1g $52.6 2026-04-30 Buy
TCI Chemical H0467 1-(Heptafluorobutyryl)imidazole [Acylating Agent] >97.0%(GC)(T) 32477-35-3 5g $110 2026-04-30 Buy
TCI Chemical H0467 1-(Heptafluorobutyryl)imidazole [Acylating Agent] >97.0%(GC)(T) 32477-35-3 25g $447 2026-04-30 Buy
Product number Packaging Price Buy
74382 1ml $115 Buy
74382 10x1ml $739 Buy
556645 1g $52.6 Buy
H0467 5g $110 Buy
H0467 25g $447 Buy

N-Heptafluorobutyrylimidazole Chemical Properties, Uses, Production

Chemical Properties

N-Heptafluorobutyrylimidazole is colorless liquid

Uses

1-(Heptafluorobutyryl)imidazole is used in gas chromatography for the determination of various pharmaceutical compounds like retronecine in biological matrixes. It acts as a reagent for derivatize amine-groups. It plays an essential role to reduce GC column degradation due to its non-acidic property. It is an acylating agent, which converts thermally unstable compounds to its more volatile derivative and then made suitable for GC analysis.

Uses

N-Heptafluorobutyrylimidazole is a derivatization agent used in gas chromatography for determination of various pharmaceutical compounds such as retronecine in biological matrixes.

General Description

May form a precipitate and may darken on storage-will not effect performance.

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

Biochem/physiol Actions

Mild amine-group derivatizing reagent; non-acidic by-product prevents decomposition and reduces GC column degradation.

336-59-4
32477-35-3
Synthesis of N-Heptafluorobutyrylimidazole from Heptafluorobutyric anhydride

N-Heptafluorobutyrylimidazole Preparation Products And Raw materials

Global Suppliers ( 233)
Supplier Tel Email Country ProdList Advantage
Shanghai daoyang technology co., ltd QQ:3150471267 13381681725 3150471267@qq.com China 473 58
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Hangzhou Fuze Pharmaceutical Technology Co., Ltd. 0572-0571-82870240 13586109179 47302108@qq.com China 264 58
Shanghai Boyle Chemical Co., Ltd. sales@boylechem.com China 2915 55
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44852 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64

View Latest Price from N-Heptafluorobutyrylimidazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-Heptafluorobutyrylimidazole pictures 2026-09-02 N-Heptafluorobutyrylimidazole
32477-35-3
$5.00 1KG 98% Henan Fengda Chemical Co., Ltd
N-Heptafluorobutyrylimidazole pictures 2019-07-06 N-Heptafluorobutyrylimidazole
32477-35-3
$1.00 1KG 97% 200KG Career Henan Chemical Co
N-(HEPTAFLUORO-N-BUTYRYL)IMIDAZOLE N-HEPTAFLUOROBUTANOYLIMIDAZOLE N-HEPTAFLUOROBUTYRYLIMIDAZOLE N-Heptafluorobutyryl-imidazole 98+ 1-(Heptafluorobutyryl)imidazole, 98+% 2,2,3,3,4,4,4-Heptafluoro-1-(1H-imidazol-1-yl)butan-1-one, HFBI, 1-(Heptafluorobutyryl)-1H-imidazole 1-(Heptafluorobutyryl)imidazole [Acylating Agent] 1-(Heptafluorobutyryl)-1H-imidazole 1-(Heptafluorobutyryl)imidazole,1-(Perfluorobutyryl)imidazole 1-(Perfluorobutanoyl)-1H-imidazole 97% 1-(Perfluorobutanoyl)-1H-imidazole 99+% 2,2,3,3,4,4,4-Heptafluoro-1-(1H-imidazol-1-yl)butan-1-one, HFBI 2,2,3,3,4,4,4-Heptafluoro-1-(1H-iMidazol-1-yl)-1-butanone NSC 151966 Heptafluorobutyric iMidazole 2,2,3,3,4,4,4-Heptafluoro-1-(1H-imidazol-1-yl)butan-1-one, HFBI, Heptafluorobutyrylimidazole HFBI (Heptafluorobutyryl iMidazole) 2,2,3,3,4,4,4-heptafluoro-1-(1H-iMidazol-1-yl)butan-1-one 2,2,3,3,4,4,4-heptafluoro-1-imidazol-1-ylbutan-1-one 2,2,3,3,4,4,4-Heptafluoro-1-(1H-imidazol-1-yl) 1H-Imidazole, 1-(2,2,3,3,4,4,4-heptafluoro-1-oxobutyl)- 1-(PERFLUOROBUTYRYL)IMIDAZOLE 1-(HEPTAFLUOROBUTYRYL)IMIDAZOLE 1-(2,2,3,3,4,4,4-heptafluoro-1-oxobutyl)-1H-imidazole N-HEPTAFLUOROBUTYRYLIMIDAZOLE 98% HeptafluoroButyrylimidazole99+% N-(HEPTAFLUORO-N-BUTYRYL)IMIDAZOLE[ACYLATINGAGENT] Heptafluorobutyrylimidazole 97% N-Heptafluorobutanoylimidazole, 97+% 1-(1,2,3,4,4,5,5-heptafluoro-2-imidazolidinyl)-1-butanone 1-(HeptafL uorobutyryL 1-(Heptafluorobutyryl)imidazole[AcylatingAgent]> 1-Butanone, 2,2,3,3,4,4,4-heptafluoro-1-(1H-imidazol-1-yl)- N-Heptafluorobutyryl-Imidazole, 98&plus HEPTAFLUOROBUTYRYLIMIDAZOLE N-Heptafluorobutyrylimidazole 1-(Perfluorobutanoyl)-1H-imidazole HFBI N-(Perfluorobutyryl)imidazole 32477-35-3 12477-35-3 C7H3F7N2O Building Blocks Biochemicals and Reagents BioChemical GC Derivatizing Reagents Acylation (GC Derivatizing Reagents) Luminescent Compounds/Detection Heterocyclic Building Blocks Derivatization agents Imidazoles Acylation Reagent Imidazol&Benzimidazole Acylation (GC Derivatizing Reagents) Analytical Chemistry GC Derivatizing Reagents Acylation ReagentsBiochemicals and Reagents