ChemicalBook >> CAS DataBase List >>PF 04995274
PF 04995274
- CAS No.
- 1331782-27-4
- Chemical Name:
- PF 04995274
- Synonyms
- PF 04995274;PF04995274;PF 04995274;PF-04995274 >=98% (HPLC);4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol;2H-Pyran-4-ol, tetrahydro-4-[[4-[[[4-[[(3R)-tetrahydro-3-furanyl]oxy]-1,2-benzisoxazol-3-yl]oxy]methyl]-1-piperidinyl]methyl]-;Inhibitor,5-HT4,5-hydroxytryptamine Receptor,behavior,Alzheimer′s disease,PF-04995274,inhibit,PF04995274,Serotonin Receptor,5-HT Receptor,Stress-induced,PF 04995274,depressive-like
- CBNumber:
- CB42668576
- Molecular Formula:
- C23H32N2O6
- Molecular Weight:
- 432.51
- MDL Number:
- MOL File:
- 1331782-27-4.mol
Last updated:2023-09-20 16:43:00
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO:20.0(Max Conc. mg/mL);46.2(Max Conc. mM) |
| form | A crystalline solid |
| FDA UNII | XI179PG9LV |
PF 04995274 price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28776 | PF-04995274 | 1331782-27-4 | 5mg | $100 | 2024-03-01 | Buy |
| Cayman Chemical | 28776 | PF-04995274 | 1331782-27-4 | 25mg | $412 | 2024-03-01 | Buy |
| Cayman Chemical | 28776 | PF-04995274 | 1331782-27-4 | 1mg | $34 | 2024-03-01 | Buy |
| Cayman Chemical | 28776 | PF-04995274 | 1331782-27-4 | 10mg | $183 | 2024-03-01 | Buy |
| ChemScene | CS-0007316 | PF-04995274 99.42% | 1331782-27-4 | 25mg | $250 | 2021-12-16 | Buy |
PF 04995274 Chemical Properties,Uses,Production
Description
PF-04995274 is a partial agonist of the serotonin (5-HT) receptor subtypes 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E (Kis = 0.36, 0.46, 0.15, and 0.32 nM, respectively, in a radioligand binding assay). It increases cAMP levels in HEK293 cells expressing 5-HT4A, 5-HT4B, 5-HT4D, and 5-HT4E receptors (EC50s = 0.47, 0.36, 0.37, and 0.26 nM, respectively, for the human recombinant receptors). PF-04995274 decreases scopolamine-induced increases in the distance traveled in the Morris water maze in rats when administered at a dose of 0.032 mg/kg.
PF 04995274 Preparation Products And Raw materials
Raw materials
Preparation Products
PF 04995274 Suppliers
Global( 36)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| Taizhou Tongxin Bio-Tech Co., Ltd | 0523-18601685-898 18652728585 | sales@allyrise.com | China | 2741 | 60 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4121 | 55 | |
| Taizhou Ruixin Chemical Co., Ltd. | 0576-89085261 15867635987 | jasonhu09@163.com | China | 442 | 50 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |
1331782-27-4(PF 04995274)Related Search:
PF-06282999
PF 4618433
PF-06650833
PF-6260933
5-PyriMidinecarboxaMide, 4-[(2-Methylpropyl)aMino]-N-(phenylMethyl)-2-[4-[(tetrahydro-2H-pyran-3-yl)Methyl]-1-piperazinyl]-
1of4
PF 04995274
PF-04995274 >=98% (HPLC)
2H-Pyran-4-ol, tetrahydro-4-[[4-[[[4-[[(3R)-tetrahydro-3-furanyl]oxy]-1,2-benzisoxazol-3-yl]oxy]methyl]-1-piperidinyl]methyl]-
PF04995274;PF 04995274
4-[[4-[[4-[(3R)-oxolan-3-yl]oxy-1,2-benzoxazol-3-yl]oxymethyl]piperidin-1-yl]methyl]oxan-4-ol
Inhibitor,5-HT4,5-hydroxytryptamine Receptor,behavior,Alzheimer′s disease,PF-04995274,inhibit,PF04995274,Serotonin Receptor,5-HT Receptor,Stress-induced,PF 04995274,depressive-like
1331782-27-4