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ChemicalBook >> CAS DataBase List >>2'-Deoxy-L-thymidine

2'-Deoxy-L-thymidine

2'-Deoxy-L-thymidine Structure
2'-Deoxy-L-thymidine structure
CAS No.
3424-98-4
Chemical Name:
2'-Deoxy-L-thymidine
Synonyms
Ldt;L-Dt;Sebivo;NV 02B;Epavudine;Aids112549;elbivudine;Aids-112549;L-Deoxythymidine;BETA-L-THYMIDINE
CBNumber:
CB4321891
Molecular Formula:
C10H14N2O5
Molecular Weight:
242.23
MDL Number:
MFCD02683612
MOL File:
3424-98-4.mol
Last updated:2023-08-17 13:06:49
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2'-Deoxy-L-thymidine Properties

Melting point 188-190°C
alpha D20 -20.3° (c = 0.192 in water)
Density 1.452±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility H2O: soluble10mg/mL (clear solution)
pka 9.55±0.10(Predicted)
form powder
color white to beige
optical activity [α]/D -15 to -22°, c = 1 in H2O
InChIKey IQFYYKKMVGJFEH-CSMHCCOUSA-N
FDA UNII 2OC4HKD3SF

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
Safety Statements  24/25
WGK Germany  3
RTECS  UV9048500
HS Code  29349990
NFPA 704
0
2 0

2'-Deoxy-L-thymidine price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0293 Telbivudine ≥98% (HPLC) 3424-98-4 5mg $130 2024-03-01 Buy
Sigma-Aldrich SML0293 Telbivudine ≥98% (HPLC) 3424-98-4 25mg $523 2024-03-01 Buy
Cayman Chemical 21453 Telbivudine 3424-98-4 10mg $100 2024-03-01 Buy
Cayman Chemical 21453 Telbivudine 3424-98-4 100mg $656 2024-03-01 Buy
Cayman Chemical 21453 Telbivudine 3424-98-4 5mg $57 2024-03-01 Buy
Product number Packaging Price Buy
SML0293 5mg $130 Buy
SML0293 25mg $523 Buy
21453 10mg $100 Buy
21453 100mg $656 Buy
21453 5mg $57 Buy

2'-Deoxy-L-thymidine Chemical Properties,Uses,Production

Description

Telbivudine is a b-L-thymidine nucleoside analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection. It is the fourth nucleoside or nucleotide analog to be marketed for this indication. The previous drugs from this class include lamivudine, a deoxythiacytosine analog, adefovir, a nucleotide analog, and entecavir, a guanosine analog. Adefovir, entecavir, and telbivudine are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections. Telbivudine is efficiently phosphorylated by cellular kinases to the active triphosphate derivative, which inhibits HBV DNA polymerase by competing with the natural substrate, thymidine- 5’-triphosphate.

Chemical Properties

2'-Deoxy-L-thymidine is White Solid

Originator

Idenix (US)

Uses

Telbivudine(Tyzeka, Sebivo) is an antiviral drug used in the treatment of hepatitis B infection. Clinical trials have shown it to be significantly more effective than lamivudine or adefovir, and less likely to cause resistance. Telbivudine is a synthetic

Uses

Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.

Definition

ChEBI: A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase.

brand name

(Novirio).

2'-Deoxy-L-thymidine Preparation Products And Raw materials

Raw materials

Preparation Products

2'-Deoxy-L-thymidine Suppliers

Global( 306)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd 		+8613288715578 sales@hbmojin.com China 12456 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		+86 18953170293 sales@sdzschem.com China 2931 58
Jinan Carbotang Biotech Co.,Ltd. 		+8615866703830 figo.gao@foxmail.com China 6992 58
Beijing Ribio Biotech Co.,Ltd 		010-62664360 +8613328773880 wucy@ribio.com.cn China 117 58
Yunbio Tech Co.,Ltd. 		+86-010-60605551 +86-18046518538 yunbiochem@126.com China 321 58
Hebei Guanlang Biotechnology Co., Ltd. 		+86-19930503282 alice@crovellbio.com China 8823 58
Supplier Advantage
Hebei Mojin Biotechnology Co., Ltd 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
SHANDONG ZHI SHANG CHEMICAL CO.LTD 		58
Jinan Carbotang Biotech Co.,Ltd. 		58
Beijing Ribio Biotech Co.,Ltd 		58
Yunbio Tech Co.,Ltd. 		58
Hebei Guanlang Biotechnology Co., Ltd. 		58

View Lastest Price from 2'-Deoxy-L-thymidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2'-Deoxy-L-thymidine pictures 2023-08-18 2'-Deoxy-L-thymidine
3424-98-4
 US $20.00 / KG 1KG 99% 50000kg Hebei Mojin Biotechnology Co., Ltd
Telbivudine pictures 2023-06-26 Telbivudine
3424-98-4
 US $200.00 / kg 1kg 99% 1000kg/Month Hebei Mingeng Biotechnology Co., Ltd
2'-Deoxy-L-thymidine pictures 2023-04-21 2'-Deoxy-L-thymidine
3424-98-4
 US $50.00 / kg 1kg 99% 100 tons Hebei Duling International Trade Co. LTD
  • Telbivudine pictures
  • Telbivudine
    3424-98-4
  • US $200.00 / kg
  • 99%
  • Hebei Mingeng Biotechnology Co., Ltd

2'-Deoxy-L-thymidine Spectrum

2'-Deoxy-L-thymidine(3424-98-4)1HNMR

3424-98-4(2'-Deoxy-L-thymidine)Related Search:

CHLOROPHOSPHONAZO III Thymidine 3'-Azido-3'-deoxy-D-thymidine Clevudine DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
3'-Deoxy-D-thymidine 3'-AMINO-3'-DEOXY-D-THYMIDINE 2',3'-Didehydro-3'-deoxy-D-thymidine 5'-AZIDO-5'-DEOXY-D-THYMIDINE 3'-Azido-3'-deoxy-D-thymidine5'-monophosphatesodiumsalt
2'-Deoxy-L-thymidine-d3 5-METHYL-1-(β-L-RIBOFURANOSYL)URACIL 3'-Azido-3'-deoxy-D-thymidine-b-D-glucuronidesodiumsalt 3'-Iodo-3'-deoxy-D-thymidine 5'-Amino-5'-deoxy-D-thymidine
2'-Deoxy-L-thymidine Deoxynucleotide Deoxidizer

1of4

2'-Deoxy-L-thyMidine(Telbivudine) Telbivudine(Tyzeka, Sebivo) 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-Methyl- Telbivudine(L-ThyMidine,LDT-600) 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione 2,4(1H,3H)-PyriMidinedione,1-(2-deoxy-b-L-erythro-pentofuranosyl)-5-Methyl- Sebivo Telbivudine(L-ThyMidine) Telbivudine, >=98% 1-(2-Deoxy--L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione 1-(2-deoxy--L-erythro-pentofuranosyl)thymine Epavudine NV 02B Aids112549 Aids-112549 L-Deoxythymidine Ldt L-Dt Thymine, 1-(2-deoxy-.beta.-L-erythro-pentofuranosyl)- BETA-L-THYMIDINE 2'-DEOXY-L-THYMIDINE L-Thymidine(Telbivudine) 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione Β-L-2'-DEOXY-THYMIDINE 1-[(2S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-methyl- elbivudine 2'-Deoxy-L-thymidine USP/EP/BP Telbivudine (Epavudine) Telbivudine 13C 15N2 Inhibitor,Telbivudine,inhibit,HBV,Hepatitis B virus 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 2'-Deoxy-L-thymidine 3424-98-4 Anti-virals Bases & Related Reagents Carbohydrates & Derivatives Intermediates & Fine Chemicals Nucleotides Pharmaceuticals API intermediates Amines API Chiral Reagents Heterocycles