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Chemical Name:
OLIGOMYCIN C;Oligmycin C;12-Deoxyoligomycin A;Oligomycin A, 12-deoxy-;OLIGOMYCIN C, STREPTOMYCES DIASTATOCHROMOGENES;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-,(1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14S,15S,16R,18E,20E,22R,25S,28S,29R)-;Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11S,12S,14S,15S,16R,18E,20E,22R,25S,28S,29R)-
Molecular Formula:
Molecular Weight:
MDL Number:
MOL File:
MSDS File:
Modify Date:2023-01-11 10:46:38


Boiling point 876.2±65.0 °C(Predicted)
Density 1.091 g/cm3
storage temp. −20°C
solubility Soluble in DMSO
form White to off-white powder.
pka 13.49±0.70(Predicted)
Merck 13,6902
EWG's Food Scores 1


Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P271
Hazard Codes  Xn
Risk Statements  22
RIDADR  2811
RTECS  RK3335000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2941900000
Toxicity LD50 ipr-mus: 8300 mg/kg JACSAT 80,6092,1958

OLIGOMYCIN C price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19162 Oligomycin C ≥95% 11052-72-5 1mg $323 2023-01-06 Buy
Cayman Chemical 19162 Oligomycin C ≥95% 11052-72-5 5mg $969 2023-01-06 Buy
TRC O532985 OligomycinC 11052-72-5 1mg $325 2021-12-16 Buy
Usbiological O6154-02 Oligomycin C 11052-72-5 1mg $523 2021-12-16 Buy
Apolloscientific BIO1007 Oligomycin C 11052-72-5 1mg $134 2021-12-16 Buy
Product number Packaging Price Buy
19162 1mg $323 Buy
19162 5mg $969 Buy
O532985 1mg $325 Buy
O6154-02 1mg $523 Buy
BIO1007 1mg $134 Buy

OLIGOMYCIN C Chemical Properties,Uses,Production


Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin C is a minor component of the oligomycin complex that acts as an inhibitor of the mitochondrial F1FO-ATP synthase. Inhibition of the ATP synthase by oligomycins leads to cell death.


Oligomycin C is an ATP synthetase and RVD inhibitor.


Oligomycin C, a minor component of the oligomycin complex isolated from selected strains of Streptomyces, is an inhibitor of mitochondrial F1F0-ATPase. It makes cells more susceptible to cell death, and also leads to a switch in the death mode from apoptosis to necrosis.

Safety Profile

A poison by intraperitoneal route.When heated to decomposition it emits acrid smoke andirritating vapors


[1]. yang p w, li m g, zhao j y, et al. oligomycins a and c, major secondary metabolites isolated from the newly isolated strain streptomyces diastaticus[j]. folia microbiologica, 2010, 55(1): 10-16.
[2]. marton a, mihalik r, bratincsák a, et al. apoptotic cell death induced by inhibitors of energy conservation[j]. european journal of biochemistry, 1997, 250(2): 467-475.

OLIGOMYCIN C Preparation Products And Raw materials

Raw materials

Preparation Products

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12-Deoxyoligomycin A Oligmycin C OLIGOMYCIN C OLIGOMYCIN C, STREPTOMYCES DIASTATOCHROMOGENES Oligomycin A, 12-deoxy- Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione, 22-ethyl-3',4',5',6'-tetrahydro-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-, (1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11S,12S,14S,15S,16R,18E,20E,22R,25S,28S,29R)- Spiro[2,26-dioxabicyclo[23.3.1]nonacosa-4,18,20-triene-27,2'-[2H]pyran]-3,9,13-trione,22-ethyl-3',4',5',6'-tetrahydro-7,11,15-trihydroxy-6'-[(2R)-2-hydroxypropyl]-5',6,8,10,12,14,16,28,29-nonamethyl-,(1R,2'R,4E,5'S,6S,6'S,7R,8S,10R,11R,12S,14S,15S,16R,18E,20E,22R,25S,28S,29R)- 11052-72-5 11053-72-5 C45H74O10 Antibiotics A to Z Antibiotics N-S BioChemical Antibiotics Antibiotics Antibiotics A to Antibiotics by Application Antibiotics N-SAntibiotics AntifungalAntibiotics Antineoplastic and Immunosuppressive AntibioticsAntibiotics Chemical Structure Class Inhibits an EnzymeAntibiotics Macrolides Mechanism of Action Spectrum of Activity