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ESTRONE 3-O-SULFAMATE

ESTRONE 3-O-SULFAMATE Structure
ESTRONE 3-O-SULFAMATE structure
CAS No.
148672-09-7
Chemical Name:
ESTRONE 3-O-SULFAMATE
Synonyms
EMATE;ESTRONE SULFAMATE;ESTRONE O-SULFAMATE;ESTRONE 3-SULFAMATE;ESTRONE 3-O-SULFAMATE;1,3,5(10)-Estratrien-17-one 3-sulfamate;Estrone sulfamate (Estrone 3-O-Sulfamate;1,3,5[10]-ESTRATRIEN-3-OL-17-ONE SULFAMATE;3-HYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE 3-SULFAMATE;3-[(AMinosulfonyl)oxy]estra-1,3,5(10)-trien-17-one
CBNumber:
CB4739432
Molecular Formula:
C18H23NO4S
Molecular Weight:
349.44
MDL Number:
MFCD00676965
MOL File:
148672-09-7.mol
Last updated:2023-05-24 08:28:53
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ESTRONE 3-O-SULFAMATE Properties

Melting point 195-197°C
Boiling point 530.9±60.0 °C(Predicted)
Density 1.314±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO, Ethanol, Methanol
form Solid
pka 8.86±0.70(Predicted)
color Pale Beige
Stability Hygroscopic

SAFETY

Risk and Safety Statements

WGK Germany  3

ESTRONE 3-O-SULFAMATE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC E889060 Estrone3-O-Sulfamate 148672-09-7 1mg $110 2021-12-16 Buy
Medical Isotopes, Inc. 9910 Estrone3-O-Sulfamate 148672-09-7 1mg $290 2021-12-16 Buy
Product number Packaging Price Buy
E889060 1mg $110 Buy
9910 1mg $290 Buy

ESTRONE 3-O-SULFAMATE Chemical Properties,Uses,Production

Chemical Properties

White to Off-White Crystalline Solid

Uses

A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM.

Purification Methods

Estrone 3-O-sulfamate [148672-09-7] M 349.5. Estrone 3-O-sulfamate is purified by silica gel flash chromatography to give a product with one spot on TLC. It is an active site-directed inhibitor of estrone sulfatase, i.e. a time-dependent enzyme inactivator. [Woo et al. J Med Chem 39 1349 1996, Purohit et al. Biochemistry 34 11508 1995.]

ESTRONE 3-O-SULFAMATE synthesis

53-16-7
148672-09-7
Synthesis of ESTRONE 3-O-SULFAMATE from Estrone

ESTRONE 3-O-SULFAMATE Preparation Products And Raw materials

Raw materials

Estrone

Preparation Products

ESTRONE 3-O-SULFAMATE Suppliers

Global( 29)Suppliers
Supplier Tel Email Country ProdList Advantage
Finetech Industry Limited 		+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9640 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 sales@tybiochem.com China 5584 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2210 55
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9649 58
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 8162 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 sales@rrkchem.com China 56086 58
Supplier Advantage
Finetech Industry Limited 		58
Aladdin Scientific 		58
Nanjing Tengyi Biotechnology Co., Ltd 58
Shanghai Boyle Chemical Co., Ltd. 55
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky（shanghai）International Co.,Ltd. 50
Finetech Industry Limited 58
Yantai ShengKailun Chemical Technology Co., Ltd. 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58

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DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) METHYL ISOCYANOACETATE Ethyl isocyanoacetate Benzyl isocyanide
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ESTRONE 3-O-SULFAMATE ESTRONE 3-SULFAMATE ESTRONE SULFAMATE ESTRONE O-SULFAMATE 3-HYDROXY-1,3,5[10]-ESTRATRIEN-17-ONE 3-SULFAMATE Estrone 3-sulfamate, Estrone O-Sulfamate, Estrone Sulfamate 1,3,5[10]-ESTRATRIEN-3-OL-17-ONE SULFAMATE 1,3,5(10)-Estratrien-17-one 3-sulfamate 3-[(AMinosulfonyl)oxy]estra-1,3,5(10)-trien-17-one EMATE Estrone sulfamate (Estrone 3-O-Sulfamate Estra-1,3,5(10)-trien-17-one, 3-[(aminosulfonyl)oxy]- 148672-09-7 BioChemical Biochemicals and Reagents Enzyme Inhibitors D to K Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Enzyme Estrone sulfatase Intermediates & Fine Chemicals Pharmaceuticals Steroids & Hormones - 13C & 2H Inhibitors Steroids