ChemicalBook >> CAS DataBase List >>CILAZAPRIL
CILAZAPRIL
- CAS No.
- 92077-78-6
- Chemical Name:
- CILAZAPRIL
- Synonyms
- Justor;Dynorm;Vascase;Initiss;Inhibace;Cilazapril CRS;CILAZAPRIL EPC(;Cilazapril Hydrate;Vascace monohydrate;ro31-2848monohydrate
- CBNumber:
- CB4771690
- Molecular Formula:
- C22H33N3O6
- Molecular Weight:
- 435.51
- MDL Number:
- MFCD01692810
- MOL File:
- 92077-78-6.mol
- MSDS File:
- SDS
Last updated:2023-05-21 10:59:17
| Melting point | 98° (dec) |
|---|---|
| alpha | D20 -62.51° (c = 1% in ethanol) |
| storage temp. | Store at -20°C |
| solubility | Slightly soluble in water, freely soluble in methanol and in methylene chloride. |
| pka | pKa1 3.3; pKa2 6.4(at 25℃) |
| FDA UNII | 19KW7PI29F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
CILAZAPRIL price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C2174000 | Cilazapril European Pharmacopoeia (EP) Reference Standard | 92077-78-6 | c2174000 | $153 | 2024-03-01 | Buy |
| Biosynth Carbosynth | FC34997 | Cilazapril monohydrate | 92077-78-6 | 25mg | $185 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC34997 | Cilazapril monohydrate | 92077-78-6 | 10mg | $95 | 2021-12-16 | Buy |
| ChemScene | CS-2448 | Cilazaprilmonohydrate 99.44% | 92077-78-6 | 10mg | $108 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC34997 | Cilazapril monohydrate | 92077-78-6 | 5mg | $60 | 2021-12-16 | Buy |
CILAZAPRIL Chemical Properties,Uses,Production
Description
Cilazapril is a new ACE inhibitor useful in the management of mild to moderate hypertension. Orally administered cilazapril is a prodrug which is de-esterified to its active diacid metabolite cilazprilat. Compared with enalapril and captopril, cilazapril is more potent and longer lasting.
Chemical Properties
White or almost white, crystalline powder.
Originator
Hoffmann-LaRoche (Switzerland)
Uses
Antihypertensive.
Definition
ChEBI: Cilazapril monohydrate is a hydrate that is the monohydrate of cilazapril. It is used for the treatment of hypertension and heart failure. It has a role as an antihypertensive agent, an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor and a prodrug. It contains a cilazapril.
brand name
Inhibace (Hoffmann-LaRoche).
CILAZAPRIL Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 63)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9126 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15396 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33350 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
View Lastest Price from CILAZAPRIL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-05-10 | Cilazapril
92077-78-6
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-13 | Cilazapril (monohydrate)
92077-78-6
|
US $1.00 / g | 1g | 95-99% | 1ton | Career Henan Chemical Co | |
 |
2020-01-13 | CILAZAPRIL
92077-78-6
|
US $1.00 / g | 1g | 99% | 200kg | Career Henan Chemical Co |
-
- Cilazapril
92077-78-6
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Cilazapril (monohydrate)
92077-78-6
- US $1.00 / g
- 95-99%
- Career Henan Chemical Co
-
- CILAZAPRIL
92077-78-6
- US $1.00 / g
- 99%
- Career Henan Chemical Co
92077-78-6(CILAZAPRIL)Related Search:
Initiss
Justor
Vascase
9[[1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]OCTAHYDRO-10-OXO-6HPYRIDAZINO[1,2-A][1,2]DIAZEPINE-1-CARBOXYLIC ACID
CILAZAPRIL EPC(
CILAZAPRIL EPC(CRM STANDARD)
CILAZAPRIL IMPURITY A1,1-DIMETHYLETHYL(1S,9S)-9-[[(S)-1-ETHOXYCARBONYL-3-PHENYLPROPYL]AMINO]-10-OXO-OCTAHYDRO-6H-PYRIDAZINO[1,2A][1,2]DIAZEPINE-1-CABOXYLATE EPC
[1S-[1α，9α(R^<*>^)]]-9-[[1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1，2-α][1，2]diazepine-1-carboxylic acid monohydrate
9-[(1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-10-oxo-1,2,3,4,6,7,8,9-oc tahydropyridazino[1,2-a]diazepine-1-carboxylic acid
Inhibace
(1S,9S)-9-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]aMino}-1-hydroxy-10-oxo-octahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
Cilazapril Monohydrate (Inhibace)
6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylicacid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]aMino]octahydro-10-oxo-,hydrate (1:1), (1S,9S)-
(1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, hydrate (1:1)
(1S,9S)-9-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate
(1S,9S)-9-{[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid hydrate (1:1)
6h-pyridazino(1,2-a)(1,2)diazepine-1-carboxylicacid,octahydro-9-((1-(ethoxyca
cilazaprilmonohydrate
hydrate,(1s-(1-alpha,9-alpha(r*)))-rbonyl)-3-phenylpropyl)amino)-10-oxo
ro31-2848monohydrate
(1s,9s)-9-[(s)-1-ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
Cilazapril Hydrate
Inhibace monohydrate
INHIBACE MONOHYDRATE;RO 31-2848 MONOHYDRATE;VASCACE MONOHYDRATE
Vascace monohydrate
Cilazapril CRS
(1S,9S)-9-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)amino)-10-oxooctahydro-1H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid
Cilazapril Monohydrate (Ro 31-2848)
(1S,9S)-9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-10-oxooctahydro-6h-pyridazino[1,2-a][1,2]diazepine-1-carboxylicacidmonohydrate
Dynorm
92077-78-6
C22H31N3O5H2O
Inhibitors