ChemicalBook >> CAS DataBase List >>Polymyxin B

Polymyxin B

CAS No.
1404-26-8
Chemical Name:
Polymyxin B
Synonyms
Polymyxin E see Colistin;polymyxin B 2.5sulfate entahydrate;Glucosamine Hydrochloride Impurity 32;Polymyxin B (base and/or unspecified salts)
CBNumber:
CB4902083
Molecular Formula:
C55H96N16O13
Molecular Weight:
0
MDL Number:
MFCD01775374
MOL File:
Mol file
MSDS File:
SDS
Last updated:2024-04-12 23:00:59

Polymyxin B Properties

alpha 5461 -106.3° (1N HCl)
FDA UNII J2VZ07J96K

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501

Polymyxin B Chemical Properties,Uses,Production

Description

Polymyxin B was isolated by Wellcome Research Laboratories, in 1949, from the mixture of polymyxins A, B, C, and D produced byBacillus polymyxa. It was later separated into the major component, B1, and the minor component, B2. Polymyxin B is a basic polypeptide and shows strong activity against gram-negative bacteria, but its activity against gram-positive bacteria, Mycobacterium, and fungi is weak. Because of its toxicity, it is used carefully by intramuscular injection for resistant Pseudomonas aeruginosa infections, e.g., sepsis. Polymyxin B is used orally to sterilize the gut in leukemic patients, intraspinally for meningitis, or topically.

Uses

Antibacterial Aerosporin.

Definition

ChEBI: A polymyxin having a 6-methylheptanoyl group at the amino terminus.

brand name

(GlaxoSmithKline); Poly-Rx (X Gen).

Contact allergens

Active against Gram-negative bacteria, Polymyxin B is a mixture of Polymyxin B1 and B2. Sensitization occurs by topical, ophthalmic, and otic preparations. Cosensitization is frequent with other topical antibiotics like neomycin or bacitracin.

Polymyxin B Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 99)Suppliers
Supplier Tel Email Country ProdList Advantage
Firsky International Trade (Wuhan) Co., Ltd
+8615387054039 admin@firsky-cn.com China 436 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177 sarah@tnjone.com China 893 58
TianYuan Pharmaceutical CO.,LTD
+86-755-23284190 13684996853 sales@tianpharm.com CHINA 304 58
Career Henan Chemica Co
+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
ANHUI WITOP BIOTECH CO., LTD
+8615255079626 eric@witopchemical.com China 23556 58
Shenzhen Shengda Pharma Limited
755-85269922 +8613424394241 sales@shengdapharm.com CHINA 310 58
Wuhan wingroup Pharmaceutical Co., Ltd
+86-13296627870; +8613296627870 info@whwingroup.com China 703 58
Hebei Duling International Trade Co. LTD
+8618032673083 sales05@hbduling.cn China 15745 58
Nantong HI-FUTURE Biology Co., Ltd.
+undefined18051384581 sales@chemhifuture.com China 3136 58

View Lastest Price from Polymyxin B manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Polymyxin B2 pictures 2024-04-12 Polymyxin B2
1404-26-8
US $0.00 / kg 1kg 99% 10000kg Shaanxi TNJONE Pharmaceutical Co., Ltd
Polymyxin B pictures 2023-10-08 Polymyxin B
1404-26-8
US $30.00 / KG 1KG 99% 20T Firsky International Trade (Wuhan) Co., Ltd
Polymyxin B pictures 2023-09-12 Polymyxin B
1404-26-8
US $100.00 / bag 1bag 99 5000 Hebei Fengqiang Trading Co., LTD
  • Polymyxin B2 pictures
  • Polymyxin B2
    1404-26-8
  • US $0.00 / kg
  • 99%
  • Shaanxi TNJONE Pharmaceutical Co., Ltd
  • Polymyxin B pictures
  • Polymyxin B
    1404-26-8
  • US $30.00 / KG
  • 99%
  • Firsky International Trade (Wuhan) Co., Ltd
  • Polymyxin B pictures
  • Polymyxin B
    1404-26-8
  • US $100.00 / bag
  • 99
  • Hebei Fengqiang Trading Co., LTD
polymyxin B 2.5sulfate entahydrate Polymyxin B (base and/or unspecified salts) Polymyxin E see Colistin Glucosamine Hydrochloride Impurity 32 1404-26-8 C43H82N16O12