Polymyxin B
- CAS No.
- 1404-26-8
- Chemical Name:
- Polymyxin B
- Synonyms
- Polymyxin E see Colistin;polymyxin B 2.5sulfate entahydrate;Glucosamine Hydrochloride Impurity 32;Polymyxin B (base and/or unspecified salts)
- CBNumber:
- CB4902083
- Molecular Formula:
- C55H96N16O13
- Molecular Weight:
- 0
- MDL Number:
- MFCD01775374
- MOL File:
- Mol file
- MSDS File:
- SDS
alpha | 5461 -106.3° (1N HCl) |
---|---|
FDA UNII | J2VZ07J96K |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P330-P501 |
Polymyxin B Chemical Properties,Uses,Production
Description
Polymyxin B was isolated by Wellcome Research Laboratories, in 1949, from the mixture of polymyxins A, B, C, and D produced byBacillus polymyxa. It was later separated into the major component, B1, and the minor component, B2. Polymyxin B is a basic polypeptide and shows strong activity against gram-negative bacteria, but its activity against gram-positive bacteria, Mycobacterium, and fungi is weak. Because of its toxicity, it is used carefully by intramuscular injection for resistant Pseudomonas aeruginosa infections, e.g., sepsis. Polymyxin B is used orally to sterilize the gut in leukemic patients, intraspinally for meningitis, or topically.
Uses
Antibacterial Aerosporin.
Definition
ChEBI: A polymyxin having a 6-methylheptanoyl group at the amino terminus.
brand name
(GlaxoSmithKline); Poly-Rx (X Gen).
Contact allergens
Active against Gram-negative bacteria, Polymyxin B is a mixture of Polymyxin B1 and B2. Sensitization occurs by topical, ophthalmic, and otic preparations. Cosensitization is frequent with other topical antibiotics like neomycin or bacitracin.
Polymyxin B Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 893 | 58 |
TianYuan Pharmaceutical CO.,LTD | +86-755-23284190 13684996853 | sales@tianpharm.com | CHINA | 304 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
Shenzhen Shengda Pharma Limited | 755-85269922 +8613424394241 | sales@shengdapharm.com | CHINA | 310 | 58 |
Wuhan wingroup Pharmaceutical Co., Ltd | +86-13296627870; +8613296627870 | info@whwingroup.com | China | 703 | 58 |
Hebei Duling International Trade Co. LTD | +8618032673083 | sales05@hbduling.cn | China | 15745 | 58 |
Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
View Lastest Price from Polymyxin B manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-12 | Polymyxin B2
1404-26-8
|
US $0.00 / kg | 1kg | 99% | 10000kg | Shaanxi TNJONE Pharmaceutical Co., Ltd | ||
2023-10-08 | Polymyxin B
1404-26-8
|
US $30.00 / KG | 1KG | 99% | 20T | Firsky International Trade (Wuhan) Co., Ltd | ||
2023-09-12 | Polymyxin B
1404-26-8
|
US $100.00 / bag | 1bag | 99 | 5000 | Hebei Fengqiang Trading Co., LTD |
- Polymyxin B2
1404-26-8
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
- Polymyxin B
1404-26-8
- US $30.00 / KG
- 99%
- Firsky International Trade (Wuhan) Co., Ltd
- Polymyxin B
1404-26-8
- US $100.00 / bag
- 99
- Hebei Fengqiang Trading Co., LTD
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