LICOCHALCONE-A
- CAS No.
- 58749-22-7
- Chemical Name:
- LICOCHALCONE-A
- Synonyms
- Glycyrrhiza chalcone A;CS-919;LICOCHALCONE-A;Licocgalcone-A;Licoricchalcone A;Licochalcone A-RM;7-Dimethoxycoumarin;Licorice Chalcone A;Licochalcone A, >99%;Licochalcone A, >=98%
- CBNumber:
- CB5114580
- Molecular Formula:
- C21H22O4
- Molecular Weight:
- 338.4
- MDL Number:
- MFCD01417903
- MOL File:
- 58749-22-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 100° |
|---|---|
| Boiling point | 532.6±50.0 °C(Predicted) |
| Density | 1.171±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility |
DMF:25.0(Max Conc. mg/mL);73.88(Max Conc. mM) DMSO:37.67(Max Conc. mg/mL);111.31(Max Conc. mM) Ethanol:43.5(Max Conc. mg/mL);128.54(Max Conc. mM) |
| pka | 7.82±0.15(Predicted) |
| form | Yellow solid |
| color | Yellow-orange |
| BRN | 4534154 |
| InChI | InChI=1S/C21H22O4/c1-5-21(2,3)17-12-15(20(25-4)13-19(17)24)8-11-18(23)14-6-9-16(22)10-7-14/h5-13,22,24H,1H2,2-4H3/b11-8+ |
| InChIKey | KAZSKMJFUPEHHW-DHZHZOJOSA-N |
| SMILES | C(C1=CC=C(O)C=C1)(=O)/C=C/C1=CC(C(C)(C)C=C)=C(O)C=C1OC |
| FDA UNII | JTV5467968 |
| NCI Drug Dictionary | licochalcone A |
| UNSPSC Code | 41116107 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332 | |||||||||
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352+P312-P304+P340+P312 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22 | |||||||||
| Safety Statements | 36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UB8755000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
|||||||||
| NFPA 704 |
|
LICOCHALCONE-A price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL80486 | Licochalcone A phyproof? Reference Substance | 58749-22-7 | 10MG | $506 | 2026-04-30 | Buy |
| Sigma-Aldrich | 435800 | Licochalcone-A, Synthetic | 58749-22-7 | 10mg | $122 | 2026-04-30 | Buy |
| Sigma-Aldrich | 435800 | Licochalcone-A, Synthetic | 58749-22-7 | 50mg | $445 | 2026-04-30 | Buy |
| TCI Chemical | L0261 | Licochalcone A | 58749-22-7 | 5MG | $98 | 2026-04-30 | Buy |
| TCI Chemical | L0261 | Licochalcone A | 58749-22-7 | 25MG | $293 | 2026-04-30 | Buy |
LICOCHALCONE-A Chemical Properties, Uses, Production
Chemical Properties
Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of licorice.
Uses
Licochalcone A is an estrogenic flavonoid that induces apoptosis in multiple types of cancer cells. Licochalcone A applied to bone marrow mesenchymal stem cells (BMSC)-aggregate has strong osteogenetic differentiation thus providing a promising strategy in treating osteoporotic weight-bearing bone fractures with defects.
Definition
ChEBI: Licochalcone A is a member of chalcones.
General Description
An estrogenic flavanoid with anti-tumor and anti-parasitic properties. Shown to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Also induces cell differentiation and enhances the effect of paclitaxel and vinblastine chemotherapy. Reported to interfere with parasite mitochondrial electron transport chain and energy metabolism.
Biochem/physiol Actions
Inhibits vegetative growth of spore-forming bacteria, B. subtilis and other food-contaminating microorganisms.
LICOCHALCONE-A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Nakeli Biotechnology Co., Ltd. | 028-61983833 19138982515 | 3265827856@qq.com | China | 1584 | 58 |
| Nanjing Peiwill Biotechnology Co.,Ltd. | 025-57027729 15850702895 | 15850702895@163.com | China | 89 | 55 |
| Nanjing puyi biotechnology co., LTD | 13814510036 | 927565933@qq.com | China | 1933 | 58 |
| Nanjing Yuanzhi Biotechnology Co. Ltd. | 15805159960; | 1211550495@qq.com | China | 1797 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7715 | 56 |
| Nanjing Spring & Autumn Biological Engineering Co., Ltd. | 17388075642 13815430202 | sale02@cqherb.com | China | 261 | 59 |
| Nanjing Bencao Yikang Biotechnology Co., Ltd | 025-69790911 18362932668 | 522593521@qq.com | China | 1163 | 58 |
| Xi'an Hongtaiyuan Biotechnology Co., Ltd | 15829065593; 15829065593 | hty15829065593@qq.com | China | 167 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
View Latest Price from LICOCHALCONE-A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-25 | Licochalcone A
58749-22-7
|
$2.00-5.00 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
 |
2026-07-27 | Licochalcone A
58749-22-7
|
$50.00 | 99.65% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-05-22 | Licochalcone A
58749-22-7
|
1kg | 5% 10% 50% 98% 99% | 1000 kg | BINBOBIO CO., LTD. |
-
- Licochalcone A
58749-22-7
- $2.00-5.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- Licochalcone A
58749-22-7
- $50.00
- 99.65%
- TargetMol Chemicals Inc.
-
- Licochalcone A
58749-22-7
- $0.00
- 5% 10% 50% 98% 99%
- BINBOBIO CO., LTD.
