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koumine

koumine structure

CAS No.: 1358-76-5

Chemical Name:: koumine

Synonyms: koumine;(3R,7alpha,20alpha)-1,2,18,19-Tetradehydro-3,17-epoxy-7,20(2H,19H)cyclovobasan;7,20(2H,19H)-Cyclovobasan, 1,2,18,19-tetradehydro-3,17-epoxy-, (3R,7alpha,20alpha)-;(3S,4S,4aR,6R,11bS,11cS)-2-Methyl-11c-vinyl-1,2,3,4,4a,5,6,11c-octahydro-6,4-(epoxymethano)-3,11b-methanopyrido[4,3-c]carbazole;6,4-(Epoxymethano)-3,11b-methano-11bH-pyrido[4,3-c]carbazole, 11c-ethenyl-1,2,3,4,4a,5,6,11c-octahydro-2-methyl-, (3S,4S,4aR,6R,11bS,11cS)-

CBNumber:: CB31480541

Molecular Formula:: C20H22N2O

Molecular Weight:: 306.4

MDL Number:: MFCD11111448

MOL File:: 1358-76-5.mol

Last updated:2023-04-23 13:52:06

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koumine Properties

Melting point	168℃
Boiling point	436.5±45.0 °C(Predicted)
Density	1.42
storage temp.	2-8°C
solubility	DMSO : 31.25 mg/mL (101.99 mM; Need ultrasonic)
form	powder
pka	8.67±0.40(Predicted)
color	Yellow-brown

koumine price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Usbiological	300533	Koumine	1358-76-5	10mg	$439	2021-12-16	Buy
TRC	K655750	Koumine	1358-76-5	100mg	$2310	2021-12-16	Buy
ApexBio Technology	N2312	Koumine	1358-76-5	20mg	$450	2021-12-16	Buy
Biosynth Carbosynth	FK73903	Koumine	1358-76-5	100mg	$867	2021-12-16	Buy
Biorbyt Ltd	orb594062	Koumine	1358-76-5	20mg	$550.8	2021-12-16	Buy

Product number	Packaging	Price	Buy
300533	10mg	$439	Buy
K655750	100mg	$2310	Buy
N2312	20mg	$450	Buy
FK73903	100mg	$867	Buy
orb594062	20mg	$550.8	Buy

koumine Chemical Properties,Uses,Production

Description

The Chinese drug 'Kou-wen', said to be derived from Gelsemium elegans Benth., is stated to contain this alkaloid which forms rhombic prisms from Me2 CO. It has [α]²³_D - 265° (EtOH) and forms a crystalline hydrochloride, m.p. 255°C (dec.) and a hydrobromide, m.p. 269°C (dec.).

Occurrence

Koumine is an alkaloid isolated from Gelsemium elegans Benth.

Uses

Koumine is known to attenuate the lipopolysaccharide-stimulated inflammation in RAW264.7 macrophages.

References

Chou, Pak, Hou., Chin. 1. Physiol., 5, 345 (1931)
Chou, Wang, Chen., ibid, 8,40 (1934)
Chi, Kao, Huang., 1. Amer. Chem. Soc., 60, 1723 (1938)

koumine Preparation Products And Raw materials

Raw materials

Preparation Products

koumine Suppliers

Global( 155)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253	jancyzheng@gcgreenpure.com	China	952	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu Greenpure Biopharma CO.,Ltd	58
career henan chemical co	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Shaanxi Pioneer Biotech Co., Ltd .	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
Shanghai Standard Technology Co., Ltd.	58

View Lastest Price from koumine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-02-24	Koumine 1358-76-5	US $0.00 / mg	5mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.
2021-07-02	koumine 1358-76-5	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd
2019-07-06	koumine 1358-76-5	US $1.00 / KG	1g	99%	100KG	Career Henan Chemical Co

Koumine
1358-76-5
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

koumine
1358-76-5
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

koumine
1358-76-5
US $1.00 / KG
99%
Career Henan Chemical Co

koumine Spectrum

koumine(1358-76-5)¹HNMR

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Cianidanol koumine 3-SPIRAL INDOLE-4-PIPERIDINE

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koumine (3R,7alpha,20alpha)-1,2,18,19-Tetradehydro-3,17-epoxy-7,20(2H,19H)cyclovobasan 7,20(2H,19H)-Cyclovobasan, 1,2,18,19-tetradehydro-3,17-epoxy-, (3R,7alpha,20alpha)- 6,4-(Epoxymethano)-3,11b-methano-11bH-pyrido[4,3-c]carbazole, 11c-ethenyl-1,2,3,4,4a,5,6,11c-octahydro-2-methyl-, (3S,4S,4aR,6R,11bS,11cS)- (3S,4S,4aR,6R,11bS,11cS)-2-Methyl-11c-vinyl-1,2,3,4,4a,5,6,11c-octahydro-6,4-(epoxymethano)-3,11b-methanopyrido[4,3-c]carbazole 1358-76-5 58-76-5 Alkaloids chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract