quinaldopeptin
- CAS No.
- 130743-07-6
- Chemical Name:
- quinaldopeptin
- Synonyms
- quinaldopeptin;BMY 28662, BU 3845T;Quinaldopeptin (9CI)
- CBNumber:
- CB51318925
- Molecular Formula:
- C62H78N14O14
- Molecular Weight:
- 1243.38
- MDL Number:
- MFCD08061897
- MOL File:
- 130743-07-6.mol
- MSDS File:
- SDS
quinaldopeptin price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 28167 | Quinaldopeptin | 130743-07-6 | 500μg | $401 | 2024-03-01 | Buy |
Cayman Chemical | 28167 | Quinaldopeptin | 130743-07-6 | 2.5mg | $1502 | 2024-03-01 | Buy |
Usbiological | Q0965 | Quinaldopeptin | 130743-07-6 | 500ug | $582 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0019178 | QUINALDOPEPTIN 95.00% | 130743-07-6 | 0.5MG | $646 | 2021-12-16 | Buy |
quinaldopeptin Chemical Properties,Uses,Production
Description
Quinaldopeptin is a quinomycin antibiotic. It is active against a variety of bacteria, including S. pyogenes, S. aureus, C. perfringens, S. faecalis, E. coli, and K. pneumoniae (MICs = 0.2, 0.4, 0.8, 1.6, 3.1, and 6.3 μg/ml, respectively). It is cytotoxic to B16/F10 and Moser cells (IC50s = 0.0008 and 0.04 μg/ml, respectively) and increases survival in a P388 leukemia mouse model. Quinaldopeptin is a bis-intercalator depsipeptide (NPBID) that binds to and intercalates into DNA (Kd = 32 nM).
Uses
Quinaldopeptin is a bis-intercalating cyclic peptide antibiotic.
Uses
Quinaldopeptin is a symmetrical, cyclic decapeptide from an Amycolatopsis sp. that is a bis-intercalator of DNA, exhibiting strong in vitro antimicrobial and cytotoxic activity. Quinaldopeptin significantly prolongs the survival time of mice inoculated with a murine tumour, and also shows weak nematocidal activity. Quinaldopeptin is related to the luzopeptins and sandramycin.
quinaldopeptin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9707 | 58 |
Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 56086 | 58 |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
Meng Cheng Technology (Shanghai) Co., LTD | 400-820-6829 | sales@mitachieve.com | China | 8864 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |