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ChemicalBook >> CAS DataBase List >>1-Methyl-1H-1,2,3-triazole-5-carbaldehyde

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde Structure
1-Methyl-1H-1,2,3-triazole-5-carbaldehyde structure
CAS No.
202931-88-2
Chemical Name:
1-Methyl-1H-1,2,3-triazole-5-carbaldehyde
Synonyms
3-methyltriazole-4-carbaldehyde;1-Methyl-1H-1,2,3-triazole-5-carbaldehyde;3-Methyl-3H-[1,2,3]triazole-4-carbaldehyde;1H-1,2,3-Triazole-5-carboxaldehyde, 1-methyl-
CBNumber:
CB52595875
Molecular Formula:
C4H5N3O
Molecular Weight:
111.1
MDL Number:
MFCD10696346
MOL File:
202931-88-2.mol
MSDS File:
SDS
Last updated:2026-05-28 03:23:05
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1-Methyl-1H-1,2,3-triazole-5-carbaldehyde Properties

Boiling point 253.5±32.0 °C(Predicted)
Density 1.31±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -0.22±0.10(Predicted)
Appearance Colorless to off-white Solid-Liquid Mixture

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H335-H315-H319
Precautionary statements  P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS114604 1-Methyl-1H-1,2,3-triazole-5-carbaldehyde 95% 202931-88-2 100mg $267 2026-06-04 Buy
Activate Scientific AS114604 1-Methyl-1H-1,2,3-triazole-5-carbaldehyde 95% 202931-88-2 250mg $294 2026-06-04 Buy
Activate Scientific AS114604 1-Methyl-1H-1,2,3-triazole-5-carbaldehyde 95% 202931-88-2 1g $686 2026-06-04 Buy
Matrix Scientific 133373 1-Methyl-1H-1,2,3-triazole-5-carbaldehyde 202931-88-2 250.00mg $1620 2026-05-18 Buy
Synthonix M40133 1-Methyl-1H-1,2,3-triazole-5-carbaldehyde 95+% 202931-88-2 100mg $120 2026-05-06 Buy
Product number Packaging Price Buy
AS114604 100mg $267 Buy
AS114604 250mg $294 Buy
AS114604 1g $686 Buy
133373 250.00mg $1620 Buy
M40133 100mg $120 Buy

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde Chemical Properties, Uses, Production

Synthesis

1-Methyl-1,2,3-triazole

16681-65-5

N,N-Dimethylformamide

68-12-2

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde

202931-88-2

1.6 M n-butyllithium (0.9 mL, 1.4 mmol) was added slowly and dropwise to a tetrahydrofuran (THF, 10 mL) solution of 1-methyl-1H-1,2,3-triazole (32.0 mg, 1.2 mmol) at -78 °C, ensuring that the reaction temperature was maintained below -60 °C. After the reaction mixture was stirred continuously at -78 °C for 30 min, N,N-dimethylformamide (0.14 mL, 1.8 mmol) was added. Subsequently, the reaction system was slowly warmed to room temperature and stirring was continued for 1 hour. Upon completion of the reaction, the reaction was quenched with water and extracted with ethyl acetate (3 × 10 mL). The organic phases were combined, washed with water (3 x 10 mL), dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with an eluent ratio of 95:5 to 100:0 dichloromethane to methanol, resulting in 1-methyl-1H-1,2,3-triazole-5-carboxaldehyde as a yellow oil (40 mg, 30% yield).1H NMR (CDCl3) data: δ 4.10 (s, 3H), 7.88 (s, 1H), 9.55 (s, 1H). 1H).

References

[1] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 6, p. 650 - 654
[2] Patent: WO2008/135826, 2008, A2. Location in patent: Page/Page column 157; 158
[3] Patent: US2014/107094, 2014, A1. Location in patent: Paragraph 0625; 0626
[4] Patent: US2015/105372, 2015, A1. Location in patent: Paragraph 0304; 0305
[5] Patent: WO2015/57206, 2015, A1. Location in patent: Page/Page column 74; 75

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde Preparation Products And Raw materials

Raw materials

1-Methyl-1,2,3-triazole N,N-Dimethylformamide Tetrahydrofuran n-Butyllithium

Preparation Products

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde Suppliers

Global Suppliers ( 34)
Supplier Tel Email Country ProdList Advantage
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10265 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 13913916777 cfzhang@aikonchem.com China 19902 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
SynAsst Chemical. 021-60343070 China 12731 55
Shanghai Chainpharm Bio-medical Technology Co., Ltd. +86-021-61727342 13611721451 sales@chainpharm.com China 984 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Yancheng KangdiSen Pharmaceutical Co., Ltd. 13812573443;18052965989 tongbenwan22@163.com China 1975 55
Changzhou Hopschain Chemical Co.,Ltd. 85528066 13775048983 sales@hopschem.com China 31548 55
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Chengdu Saiousi Pharmaceutical Co., Ltd 028-64971018 18108168130 China 1780 55
Supplier Advantage
Hangzhou Sage Chemical Co., Ltd. 58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 55
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
SynAsst Chemical. 55
Shanghai Chainpharm Bio-medical Technology Co., Ltd. 58
Bide Pharmatech Ltd. 60
Yancheng KangdiSen Pharmaceutical Co., Ltd. 55
Changzhou Hopschain Chemical Co.,Ltd. 55
Amadis Chemical Company Limited 58
Chengdu Saiousi Pharmaceutical Co., Ltd 55

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde Spectrum

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde(202931-88-2)1HNMR

202931-88-2 (1-Methyl-1H-1,2,3-triazole-5-carbaldehyde) Related Search:

Halcinonide 1-Methyl-1H-1,2,3-triazole-5-carboxylic acid 1H-1,2,3-Triazole-5-carboxylicacid,1-methyl-,methylester(9CI) 1-Methyl-1H-1,2,3-triazole-4-carbaldehyde 1-Benzyl-1H-1,2,3-triazole-5-carbaldehyde
1-methyl-1H-1,2,3-Triazole-5-methanol

1of2

1-Methyl-1H-1,2,3-triazole-5-carbaldehyde 3-methyltriazole-4-carbaldehyde 3-Methyl-3H-[1,2,3]triazole-4-carbaldehyde 1H-1,2,3-Triazole-5-carboxaldehyde, 1-methyl- 202931-88-2