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5,6-Dichloronicotinic acid

5,6-Dichloronicotinic acid structure

CAS No.: 41667-95-2

Chemical Name:: 5,6-Dichloronicotinic acid

Synonyms: 2,3-dichloropyridine-5-carboxylic acid;5,6-DichL;5,6-Dichloro;TIMTEC-BB SBB003623;5,6-DICHLORONICOTINIC A;Avatrombopag Impurity 10;Avatroposide impurities16;5,6-DICHLORONICOTINIC ACID;5,6-DichloronicotinicAcid>5,6-Dichloronicotinic acid 97%

CBNumber:: CB5261891

Molecular Formula:: C6H3Cl2NO2

Molecular Weight:: 192

MDL Number:: MFCD00075181

MOL File:: 41667-95-2.mol

MSDS File:: SDS

Last updated:2024-05-16 10:38:37

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5,6-Dichloronicotinic acid Properties

Melting point	164-168 °C(lit.)
Boiling point	342.1±37.0 °C(Predicted)
Density	1.612±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
pka	2.87±0.10(Predicted)
form	Powder
color	White to beige to tan
BRN	383740
InChI	InChI=1S/C6H3Cl2NO2/c7-4-1-3(6(10)11)2-9-5(4)8/h1-2H,(H,10,11)
InChIKey	RNRLTTNKVLFZJS-UHFFFAOYSA-N
SMILES	C1=NC(Cl)=C(Cl)C=C1C(O)=O
CAS DataBase Reference	41667-95-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P301+P312+P330

Hazard Codes

Risk Statements

36/37/38

Safety Statements

22-24/25-36-26

WGK Germany

HazardClass

IRRITANT

HS Code

29339900

NFPA 704

	1
2		0

5,6-Dichloronicotinic acid price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	340219	5,6-Dichloropyridine-3-carboxylic acid 96%	41667-95-2	5g	$26	2023-06-20	Buy
TCI Chemical	D2401	5,6-Dichloronicotinic Acid >98.0%(T)	41667-95-2	5g	$56	2024-03-01	Buy
TCI Chemical	D2401	5,6-Dichloronicotinic Acid >98.0%(T)	41667-95-2	25g	$191	2024-03-01	Buy
Alfa Aesar	B25586	5,6-Dichloronicotinic acid, 98+%	41667-95-2	25g	$209	2021-12-16	Buy
Alfa Aesar	B25586	5,6-Dichloronicotinic acid, 98+%	41667-95-2	5g	$62.7	2021-12-16	Buy

Product number	Packaging	Price	Buy
340219	5g	$26	Buy
D2401	5g	$56	Buy
D2401	25g	$191	Buy
B25586	25g	$209	Buy
B25586	5g	$62.7	Buy

5,6-Dichloronicotinic acid Chemical Properties,Uses,Production

Chemical Properties

white to off-white crystalline powder

Uses

5,6-Dichloronicotinic acid is a dihalonicotinic acid. It is used in the preparation of 5-chloro-6-iodonicotinic acid by iodine displacement.

Application

5,6-Dichloronicotinic acid is a compound that can be synthesized by reacting methyl ketones with chloroacetic acid. It is used in the synthesis of maleic anhydride and has been shown to inhibit the catalysis of acetylcholine chloride. It has also been shown to have an inhibitory effect on Alzheimer's disease. The kinetic mechanism for this inhibition occurs through the hydrolysis step of 5,6-Dichloronicotinic acid by magnesium chloride in hexane solution. The reactive acylation reaction proceeds when it reacts with acetic anhydride in the presence of pyridine.

5,6-Dichloronicotinic acid synthesis

Synthesis of 5,6-Dichloronicotinic acid from 5,6-DICHLORONICOTINIC ACID ETHYL ESTER

5,6-Dichloronicotinic acid Preparation Products And Raw materials

Raw materials

5,6-dichloronicotinonitrile 5-Chloro-6-hydroxy-3-pyridinecarboxylic acid

Preparation Products

2,3-DICHLOROPYRIDINE-5-CARBONYL CHLORIDE 5,6-DICHLORONICOTINIC ACID ETHYL ESTER 5-Chloronicotinic acid 3-Pyridinecarboxylicacid,5,6-dimethyl-(9CI) 5-chloro-6-(cyclohexyloxy)pyridine-3-carboxylic acid

5-chloro-6-(2-methylpropoxy)pyridine-3-carboxylic acid 6-Methyl-5-(2-methylpropyl)pyridine-3-carboxylic Acid Hydrochloride 5-chloro-6-[4-(ethoxycarbonyl)piperidino]nicotinic acid tert-butyl 5,6-dichloropyridin-3-ylcarbamate 5,6-Dichloro-nicotinic acid tert-butyl ester

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5,6-Dichloronicotinic acid Suppliers

Global( 408)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88299272	info@edengenechem.com	China	2169	58
Senova Technology Co. Ltd.	+86-0755-86703119 +8618503098836	info@senovatech.com	China	350	58
Shenyang TYSChem Co., Ltd.	+86-24-83607930 +8618640359690	sales@honghuchem.com	China	403	58
Jinan Dexinjia Bio&Tech Co., Ltd	+86-0531-82375893 +86-15553111391	sales@jndxj.com	China	1201	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	6011	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	18219	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	3001	58
Frapp's ChemicalNFTZ Co., Ltd.	+86 (576) 8169-6106	sales@frappschem.com	China	885	50
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21688	55

Supplier	Advantage
Changzhou Ditong Chemical Co.,Ltd	58
Senova Technology Co. Ltd.	58
Shenyang TYSChem Co., Ltd.	58
Jinan Dexinjia Bio&Tech Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Frapp's ChemicalNFTZ Co., Ltd.	50
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55

View Lastest Price from 5,6-Dichloronicotinic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-05-31	5,6-Dichloronicotinic acid 41667-95-2	US $0.00-0.00 / kg	1kg	≥98% by HPLC	50kg/month	Zison Pharmaceutical (Shandong) Co., Ltd.
2024-04-24	5,6-Dichloronicotinic acid 41667-95-2	US $5.00 / kg	1kg	99.92%	50000tons	Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-04-11	Avatrombopag Impurity 10	US $0.00-0.00 / mg	10mg	0.98	10g	ShenZhen H&D Pharmaceutical Technology Co., LTD

5,6-Dichloronicotinic acid
41667-95-2
US $0.00-0.00 / kg
≥98% by HPLC
Zison Pharmaceutical (Shandong) Co., Ltd.

5,6-Dichloronicotinic acid
41667-95-2
US $5.00 / kg
99.92%
Ouhuang Engineering Materials (Hubei) Co., Ltd

Avatrombopag Impurity 10
US $0.00-0.00 / mg
0.98
ShenZhen H&D Pharmaceutical Technology Co., LTD

5,6-Dichloronicotinic acid Spectrum

5,6-Dichloronicotinic acid(41667-95-2)MS 5,6-Dichloronicotinic acid(41667-95-2)¹HNMR 5,6-Dichloronicotinic acid(41667-95-2)¹³CNMR 5,6-Dichloronicotinic acid(41667-95-2)IR1 5,6-Dichloronicotinic acid(41667-95-2)IR2

41667-95-2(5,6-Dichloronicotinic acid)Related Search:

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4-Chloronicotinic acid EPA Dichloroethane 2-chloro-5-cyanopyridine 2-Mercaptonicotinic acid

6-Aminonicotinic acid 2,6-DICHLORONICOTINIC ACID 98%,2 6-DICHLORONICOTINIC ACID TECH. 90%,2,6-DICHLORONICOTINIC ACID 2,5-DICHLORONICOTINIC ACID

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5,6-DICHLORO-3-PYRIDINECARBOXYLIC ACID 5,6-DICHLORONICOTINIC ACID 5,6-DICHLOROPYRIDINE-3-CARBOXYLIC ACID TIMTEC-BB SBB003623 5,6-Dichloropyridine-3-carboxylicacid,96% 5,6-Dichloro 5,6-DICHLORONICOTINIC ACID 98+% 5,6-Dichloronicotinic acid, 5,6-Dichloropyridine-3-carboxylic acid 5,6-Dichloropyridine-3-carboxylic acid, 98+% 5,6-Dichloropyridine-3-carboxylic acid, 5-Carboxy-2,3-dichloropyridine 5,6-Dichloronicotinic acid 97% 5,6-DichloronicotinicAcid> 5,6-DichL 3-Pyridinecarboxylic acid, 5,6-dichloro- Avatrombopag Impurity 10 5,6-Dichloronicotinic acid ISO 9001：2015 REACH 5,6-DICHLORONICOTINIC A 2,3-dichloropyridine-5-carboxylic acid Avatroposide impurities16 (4-cyclohexylpiperazin-1-yl)(5,6-dichloropyridin-3-yl)methanone 41667-95-2 1667-95-2 Pyridines Heterocyclic Building Blocks Halogenated Heterocycles Building Blocks Chloropyridines Halopyridines Heterocycle-Pyridine series Chloropyridines Halopyridines Pyridine Building Blocks C5 to C6 C6 to C7 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Pyridines pharmacetical Organic acids Pyridines, Pyrimidines, Purines and Pteredines Intermediate