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[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid

CAS No.
16142-03-3
Chemical Name:
[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
Synonyms
mPEG5-CH2COOH;MPEG5-OCH2COOH;m-PEG6-CH4COOH;mPEG5-acetic acid;3,6,9,12,15,18-Hexaoxa-nonadecansaeure;3,6,9,12,15,18-Hexaoxanonadecanoic acid;2,5,8,11,14,17-Hexaoxanonadecan-19-oic acid;2,5,8,11,14,17-Hexaoxa-19-nonadecanoic Acid;mPEG5-CH2COOH/3,6,9,12,15,18-Hexaoxanonadecanoic acid;[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
CBNumber:
CB52747175
Molecular Formula:
C13H26O8
Molecular Weight:
310.34
MDL Number:
MFCD30536160
MOL File:
16142-03-3.mol
Last updated:2023-03-13 11:54:02

[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Properties

Boiling point 418.6±40.0 °C(Predicted)
Density 1.124±0.06 g/cm3(Predicted)
pka 3.39±0.10(Predicted)

SAFETY

Risk and Safety Statements

[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
BroadPharm BP-23434 m-PEG6-CH2COOH 98% 16142-03-3 1g $310 2021-12-16 Buy
Activate Scientific AS104071 mPEG5-CH2COOH 95+% 16142-03-3 1g $471 2021-12-16 Buy
purepeg 363605 mPEG5-CH2COOH min.95% 16142-03-3 250mg $152 2021-12-16 Buy
Acrotein B-0958 mPEG5-CH2COOH 97% 16142-03-3 0.5g $247.5 2021-12-16 Buy
purepeg 363605 mPEG5-CH2COOH min.95% 16142-03-3 1g $275 2021-12-16 Buy
Product number Packaging Price Buy
BP-23434 1g $310 Buy
AS104071 1g $471 Buy
363605 250mg $152 Buy
B-0958 0.5g $247.5 Buy
363605 1g $275 Buy

[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Chemical Properties,Uses,Production

Description

m-PEG6-CH2COOH is a PEG linker containing a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media.

Biological Activity

m-PEG5-CH2COOH is a non-cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs). It is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

Non-cleavable

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PEGs

[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid Suppliers

Global( 52)Suppliers
Supplier Tel Email Country ProdList Advantage
9i LLC
+18039569191 MWan@NiNeiLab.com United States 418 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.
+86-021-61551413 +8618813727289 contact@trustwe.com China 5738 58
QINGDAO KAIENSI INTERNATIONAL TRADE CO.,LTD.
+86-0532-8699-9256 +8615254267723 kaley@cnfdevelop.com China 1410 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Shanxi Tihondan Pharmaceutical Technology Co., Ltd
+8618235132063 sales@tihondan.com China 3725 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Biomatrik (Jiaxing) Inc. 573-573-82623377 18967387295 sales@biomatrik.cn China 71 61
Beijing Isomersyn Technology CO;LTD 010-82954736 13391601435 sales@isomersyn.com China 3296 57

View Lastest Price from [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid pictures 2019-12-23 [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
16142-03-3
US $1.00 / KG 1KG 97%-99.9% 100kg Career Henan Chemical Co
MPEG5-OCH2COOH [2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid 3,6,9,12,15,18-Hexaoxanonadecanoic acid m-PEG6-CH4COOH mPEG5-acetic acid mPEG5-CH2COOH 2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]acetic acid 3,6,9,12,15,18-Hexaoxa-nonadecansaeure 2,5,8,11,14,17-Hexaoxanonadecan-19-oic acid mPEG5-CH2COOH/3,6,9,12,15,18-Hexaoxanonadecanoic acid 2,5,8,11,14,17-Hexaoxa-19-nonadecanoic Acid 16142-03-3 C13H26O8