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Methyl 4-methoxyacetoacetate

CAS No.
41051-15-4
Chemical Name:
Methyl 4-methoxyacetoacetate
Synonyms
4-Methoxyacetoacetate;Methyl 4-methoxy-3-oxobu;Methyl methoxyacetoacetate;Methyl 4-Methoxyacetoacetat;Dolutegravir Intermediates2;METHYL 4-METHOXYACETOACETATE;Methyl 3-oxo-4-methoxybutyrate;METHYL 4-METHOXYACETOXYACETATE;methyl 4-methoxy-3-oxobutyrate;Methyl4-Methoxyacetoacetate>
CBNumber:
CB5291234
Molecular Formula:
C6H10O4
Molecular Weight:
146.14
MDL Number:
MFCD00010183
MOL File:
41051-15-4.mol
MSDS File:
SDS
Last updated:2023-12-22 09:12:54

Methyl 4-methoxyacetoacetate Properties

Melting point -80℃
Boiling point 89 °C/8.5 mmHg (lit.)
Density 1.129 g/mL at 25 °C (lit.)
refractive index n20/D 1.431(lit.)
Flash point 193 °F
storage temp. Sealed in dry,Room Temperature
form clear liquid
pka 9.88±0.46(Predicted)
Specific Gravity 1.129
color Colorless to Light yellow to Light orange
BRN 1761215
InChIKey QGBPKJFJAVDUNC-UHFFFAOYSA-N
LogP 0.340 (est)
CAS DataBase Reference 41051-15-4(CAS DataBase Reference)
NIST Chemistry Reference Methyl 4-methoxyacetoacetate(41051-15-4)
EPA Substance Registry System Methyl 4-methoxyacetoacetate (41051-15-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
10
HS Code  29189900
NFPA 704
2
0 0

Methyl 4-methoxyacetoacetate price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 281506 Methyl 4-methoxyacetoacetate 97% 41051-15-4 5g $58.56 2024-03-01 Buy
Sigma-Aldrich 281506 Methyl 4-methoxyacetoacetate 97% 41051-15-4 25g $201 2024-03-01 Buy
TCI Chemical M1031 Methyl 4-Methoxyacetoacetate >97.0%(GC) 41051-15-4 5g $50 2024-03-01 Buy
TCI Chemical M1031 Methyl 4-Methoxyacetoacetate >97.0%(GC) 41051-15-4 25g $139 2024-03-01 Buy
TRC M320845 Methyl 4-Methoxyacetoacetate 41051-15-4 10g $165 2021-12-16 Buy
Product number Packaging Price Buy
281506 5g $58.56 Buy
281506 25g $201 Buy
M1031 5g $50 Buy
M1031 25g $139 Buy
M320845 10g $165 Buy

Methyl 4-methoxyacetoacetate Chemical Properties,Uses,Production

Chemical Properties

colorless to yellow liquid

Uses

Methyl 4-methoxyacetoacetate has been used in generation of a small focused library of diversely functionalized dihydropyrimidine derivatives via one-pot three-component Biginelli cyclocondensation of β-ketoesters, aldehydes and (thio)ureas.

Uses

Methyl 4-Methoxyacetoacetate is a reactant in the formation of an abiotic poorphyrinogen in aqueous solution.

Preparation

The preparation method of a 4-methoxyl group methyl acetoacetate: add solvents tetrahydrofurane in a kettle. and pass into rare gas element, the temperature in the kettle arranging reactor is 15-25℃, industrial sodium hydride and metal alkaline compound is added under whipped state, add solvents tetrahydrofurane again, the mixed solution reaction 4-6h of methyl alcohol and 4-chloro methyl acetoacetate is dripped in less than 20℃, then be warming up to 20-25℃ and continue reaction 4-15h, TLC detection reaction is complete, reduce system temperature to 6-10℃, add the hydrochloric acid soln regulation system pH=5-7 that volumetric molar concentration is 2mol/L, stratification, after separatory, upper strata is concentrated is spin-dried for removing solvents tetrahydrofurane, then colorless product 4-methoxyl group methyl acetoacetate is obtained by wiped film molecular distillation.

67-56-1
32807-28-6
41051-15-4
Synthesis of Methyl 4-methoxyacetoacetate from Methanol and Methyl 4-chloro-3-oxo-butanoate
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View Lastest Price from Methyl 4-methoxyacetoacetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 4-methoxyacetoacetate pictures 2023-11-02 Methyl 4-methoxyacetoacetate
41051-15-4
US $20.00-1.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
Methyl 4- Methoxyacetoacetate pictures 2023-11-01 Methyl 4- Methoxyacetoacetate
41051-15-4
US $0.00-0.00 / kg 1kg 99.0% 20 tons Hangzhou ICH Biofarm Co., Ltd
Methyl 4-methoxyacetoacetate pictures 2023-10-19 Methyl 4-methoxyacetoacetate
41051-15-4
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
4-methoxy-3-oxo-butanoicacimethylester Butanoic acid, 4-methoxy-3-oxo-, methyl ester Methyl methoxyacetoacetate 4-METHOXYACETOACETIC ACID METHYL ESTER METHYL 4-METHOXYACETOACETATE METHYL 4-METHOXYACETOXYACETATE METHYL 4-METHOXY-3-OXO-BUTANOATE 3-Oxo-4-methoxybutanoic acid methyl ester 3-Oxo-4-methoxybutyric acid methyl ester Methyl 3-oxo-4-methoxybutyrate Methyl 4-methoxyacetoacetate,98% Methyl4-methoxy-acetoacetate,97% Methyl 4-Methoxyacetoacetate, 98% 10ML 4-METHOXYACETOACETIC ACID METHYL ESTER 97+% methyl 4-methoxy-3-oxobutyrate 4-methoxy-3-oxo-butanoic acid methyl ester 4-Methoxyacetoacetate Methyl 4-methoxy-3-oxobutanoate, Methyl 4-methoxy-3-oxobutyrate M4MAA,Methyl 4-methoxyacetoacetate Methyl4-Methoxyacetoacetate> Methyl 4-Methoxyacetoacetat Dolutegravir Intermediates2 N-(3-methylphenyl)-N-(phenylmethyl)-2-(1-piperidinyl)acetamide hydrochloride Methyl 4-methoxy-3-oxobu 4-Methoxyacetoacetate methyl ester 41051-15-4 CH3OCH2COCH2COOCH3 Organic Building Blocks Esters Building Blocks Carbonyl Compounds C6 to C7 Acetics acid and esters C6 to C7 Carbonyl Compounds Esters