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Sodium levothyroxine

CAS No.
25416-65-3
Chemical Name:
Sodium levothyroxine
Synonyms
O-(4;5,5´T4 sodium salt;L-THYROXIN SODIUM;Evothyroxine Sodium;SODIUM LEVOTHYROXINE;Levothryoxine Soidum;L-THYROXINE SODIUM SALT;Levothyroxine sodium CRS;Levothyroxine SodiuM, USP
CBNumber:
CB9123791
Molecular Formula:
C15H10I4NNaO4
Molecular Weight:
798.85
MDL Number:
MFCD06408007
MOL File:
25416-65-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:45:25

Sodium levothyroxine Properties

Melting point 207 °C
alpha 16 º (c=2,1M HCl/alcohol 1/4)
storage temp. Inert atmosphere,2-8°C
solubility Very slightly soluble in water, slightly soluble in ethanol (96 per cent). It dissolves in dilute solutions of alkali hydroxides.
form Liquid
color Clear yellow to yellow-greenish
Water Solubility 0.15 g/L (25 ºC)
Stability Hygroscopic
Major Application agriculture
environmental
InChI InChI=1/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/s3
InChIKey YDTFRJLNMPSCFM-ZLBVLXFENA-M
SMILES C1(=CC(=C(O)C(I)=C1)I)OC1=C(I)C=C(C[C@H](N)C([O-])=O)C=C1I.[Na+] |&1:16,r|
CAS DataBase Reference 25416-65-3(CAS DataBase Reference)
FDA UNII 9J765S329G
UNSPSC Code 41116107

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H372
Precautionary statements  P260-P264-P270-P314-P501
target organs Thyroid,Cardio-vascular system,Kidney
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  24/25
WGK Germany  3
HS Code  29379000
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications STOT RE 1

Sodium levothyroxine price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR2880 Levothyroxine Sodium Hydrate pharmaceutical secondary standard, certified reference material 25416-65-3 100MG $171 2026-04-30 Buy
Sigma-Aldrich L0570000 Levothyroxine sodium European Pharmacopoeia (EP) Reference Standard 25416-65-3 100 mg $254 2026-04-30 Buy
Sigma-Aldrich 1365065 Levothyroxine sodium United States Pharmacopeia (USP) Reference Standard 25416-65-3 50mg $501 2026-04-30 Buy
Sigma-Aldrich L0570000 Levothyroxine sodium European Pharmacopoeia (EP) Reference Standard 25416-65-3 l0570000 $220 2024-03-01 Buy
Usbiological 291138 3,3',5,5'-Tetraiodo-L-thyronine sodium salt Asreported 25416-65-3 1g $333 2026-06-03 Buy
Product number Packaging Price Buy
PHR2880 100MG $171 Buy
L0570000 100 mg $254 Buy
1365065 50mg $501 Buy
L0570000 l0570000 $220 Buy
291138 1g $333 Buy

Sodium levothyroxine Chemical Properties, Uses, Production

Uses

L-Thyroxine sodium hydrate is a useful research chemical. Its free form Thyroxine (T425600) is one of the thyroid hormones involved in the maintenance of metabolic homeostasis. Synthesized and stored as amino acid residues of thyroglobulin, the major protein component of the thyroid follicular colloid. Synthesis and secretion are regulated by the pituitary hormone (TSH). Deiodinated in peripheral tissues to the active metabolite, liothyronine. The D-form has very little activity as a thyroid hormone, but has been used to treat hyperlipidemia.

Chemical Properties

almost white to beige or

Uses

Thyroid hormone replacement.

Definition

ChEBI: Levothyroxine sodium hydrate is an organic molecular entity.

brand name

Levo-T (Alara); Levolet (Vintage); Levothroid (Lloyd); Levoxyl (Jones); Novothyrox (Genpharm); Synthroid (Abbott); Unithroid (Stevens J).

Sodium levothyroxine Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 239)
Supplier Tel Email Country ProdList Advantage
Shanxi jiaernuo Biotechnology Co.,LTD. 19992526222 13992350171 540492555@qq.com China 23 58
Shanghai Chiral Chemicals Inc. 021-37285021 13472570865 tym7xi@aliyun.com China 299 64
Weinan Ruilin Changxin Biotechnology Co., Ltd 13892558122 13892558122 13892558122 1550396525@qq.com China 21 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
future industrial shanghai co., ltd 400-0066400 13621662912 sales@jonln.com China 1989 65
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Suzhou Ryan Pharmaceutical Technology Co., Ltd. 0512-68780025 18962125825 sales@ryanchem.com China 169 62
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14412 57
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57

View Latest Price from Sodium levothyroxine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sodium levothyroxine pictures 2025-12-24 Sodium levothyroxine
25416-65-3
1KG 98.0% 1000Tons Shaanxi Dideu Medichem Co. Ltd
Sodium levothyroxine pictures 2025-04-04 Sodium levothyroxine
25416-65-3
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
Sodium levothyroxine pictures 2025-01-04 Sodium levothyroxine
25416-65-3
$1.00 1KG 99% 1T Shaanxi Dideu Medichem Co. Ltd

Sodium levothyroxine Spectrum

SODIUM LEVOTHYROXINE SODIUM LEVOTHYROXINE, HYDRATE sodium (2s)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate 3-[4-4-HYDROXY-3,5-DIIODOPHENOXY-3,5-DIIODOPHENYL]-L-ALANINE, HYDRATE L-THYROXINE SODIUM SALT L-THYROXINE SODIUM SALT, HYDRATE L-THYROXINE SODIUM, HYDRATE L-THYROXIN SODIUM 3,3μ,5,5μ-Tetraiodo-L-thyronine hydrate monosodium salt, Sodium O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine hydrate Levothyroxine sodium hydrate L-Thyroxine sodium salt hydrate,99% L-Thyroxine sodium salt hydrateSodium levothyroxine 3,3',5,5'-Tetraiodo-L-thyronine monosodium salt hydrate LEVOTHYROXINESODIUM,HYDRATE,BP Sodium O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine hydrate Levothyroxine SodiuM, USP 5,5´ -Tetraiodo-L-thyronine sodiuM salt SodiuM levothyroxine Levothyroxine sodiuM L-Thyroxine sodiuM xhydrate L-Thyroxin monosodium salt hydrate T4 sodium salt O-(4 3,3',5,5'-Tetraiodo-L-thyronine sodium salt≥ 98% (HPLC) L-Thyroxine Sodium Salt Hydrate 99% sodium 2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate hydrate Sodium 2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo phenyl) propanoate monohydrate Levothyroxine for peak identification CRS Levothyroxine sodium CRS Sodium Levothyroxine,>98% evothyroxine sodium hydrate L-Thyroxine sodium salt hydrate, 97+% Liothyronine sodium EP Impurity A sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate trihydrate Levothyroxine for peak identification (Y0001382)Q: What is Levothyroxine for peak identification (Y0001382) Q: What is the CAS Number of Levothyroxine for peak identification (Y0001382) Levothyroxine sodium monohydrate Levothryoxine Soidum Sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate xhydrate Evothyroxine Sodium Empagliflozin Impurity 200 3,3',5,5'-Tetraiodo-L-thyronine sodium hydrate 25416-65-3 6106-7-6 551-03-8 C15H11I4NO4Na C15H10I4NNaO4xH2O C15H10I4NO4NaH2O Hormone Drugs 25416-65-3