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Silibinin

Silibinin
Silibinin structure
CAS No.
22888-70-6
Chemical Name:
Silibinin
Synonyms
ybin;7c3mt;SILYBIN;Sylibin;Mepasil;Realsil;flavobin;silliver;silybine;Silymrin
CBNumber:
CB6112194
Molecular Formula:
C25H22O10
Formula Weight:
482.44
MOL File:
22888-70-6.mol

Silibinin Properties

Melting point:
164-174°C
alpha 
D20 +11° (c = 0.25 in acetone + alcohol)
Boiling point:
793.0±60.0 °C(Predicted)
Density 
1.527±0.06 g/cm3(Predicted)
storage temp. 
-20°C
pka
pKa 6.42±0.04 (Uncertain)
Water Solubility 
54mg/L(24.99 ºC)
Merck 
13,8607
Stability:
Stable. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference
22888-70-6(CAS DataBase Reference)
EWG's Food Scores
1
FDA UNII
4RKY41TBTF
NCI Dictionary of Cancer Terms
silymarin
NCI Drug Dictionary
silymarin
SAFETY
  • Risk and Safety Statements
Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-24/25-22-36
RIDADR  3172
WGK Germany  3
RTECS  DJ2981770
HS Code  29329990
Toxicity LD50 intravenous in mouse: 1056mg/kg

Silibinin price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S0417 Silibinin ≥98% (HPLC) 22888-70-6 1g $42 2021-03-22 Buy
Sigma-Aldrich PHR2655 Silybin Pharmaceutical Secondary Standard; Certified Reference Material 22888-70-6 100MG $129 2021-03-22 Buy
Sigma-Aldrich 1612630 Silybin United States Pharmacopeia (USP) Reference Standard 22888-70-6 50mg $325 2021-03-22 Buy
Sigma-Aldrich 02000585 Silybin mixture of Silybin A and B, primary reference standard 22888-70-6 25 mg $654 2021-03-22 Buy
Cayman Chemical 10006211 Silybin ≥98% 22888-70-6 50000 mg $300 2021-03-22 Buy

Silibinin Chemical Properties,Uses,Production

Chemical Properties

solid

Originator

Legalon,Madaus,W. Germany,1969

Uses

Labelled Silybin (S465850). Hepatoprotectant.

Definition

ChEBI: A flavonolignan isolated from milk thistle, Silybum marianum, that has been shown to exhibit antioxidant and antineoplastic activities.

Manufacturing Process

Silymarin comprising polyhydroxyphenyl chromanones is recovered from the dried fruit of Silybum marianum Gaertn. by separating the fatty oils therefrom, extracting the remaining solid residue with ethyl acetate, evaporating the ethyl acetate and dissolving the dry residue in a solvent mixture comprising methanol, water and petroleum ether to form a two-phase system wherein the chromanones are contained in the lower phase, recovering the polyhydroxyphenyl chromanones from the lower phase after subjecting same to multiple counter-current contact with petroleum ether.

Therapeutic Function

Hepatoprotectant

Silibinin Preparation Products And Raw materials

Raw materials

Preparation Products


Silibinin Suppliers

Global( 424)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shaanxi Pioneer Biotech Co., Ltd .
86-13259417953(Whatsapp/Wechat) 86-13259417953(Whatsapp)
029-84385017 sales@pioneerbiotech.com CHINA 3001 58
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 21032 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
008615858145714
+86-571-56059825 fandachem@gmail.com CHINA 8882 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 890 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29961 58
Shaanxi Yikanglong Biotechnology Co., Ltd.
17791478691
yklbiotech@163.com CHINA 297 58
Chengdu Biopurify Phytochemicals Ltd.
18482058008 18080483897
maggie@biopurify.com CHINA 2712 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58

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View Lastest Price from Silibinin manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-15 Silibinin
22888-70-6
US $0.00 / KG 100g 98%+ 100kg WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
2021-09-29 Silibinin
22888-70-6
US $0.00 / KG 1KG 97.0% 50kg/month WUHAN FORTUNA CHEMICAL CO., LTD
2021-07-13 Silibinin
22888-70-6
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd

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