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ChemicalBook >> CAS DataBase List >>(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Structure
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid structure
CAS No.
1072833-77-2
Chemical Name:
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
Synonyms
IxazoMib;MLN2238;Ixazomib-d7;CS-1976;MLN2238(Ixazomib);MLN2238(iaxzomib);ixazomib(MLN2238);Ixazomib (MLN-9708);Ixazomib (10mM in DMSO);MLN2238;MLN 2238;MLN-2238
CBNumber:
CB62521080
Molecular Formula:
C14H19BCl2N2O4
Molecular Weight:
361.03
MDL Number:
MFCD18251438
MOL File:
1072833-77-2.mol
Last updated:2024-03-28 13:39:29
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(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Properties

Melting point >142°C (subl.)
Density 1.306
storage temp. -20°C Freezer
solubility DMSO (Sparingly), Methanol (Slightly)
pka 9.67±0.43(Predicted)
form Solid
color White to Pale Yellow
FDA UNII 71050168A2
ATC code L01XG03

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H362-H360
Precautionary statements  P201-P260-P263-P264-P270-P308+P313

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid price More Price(39)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18385 MLN2238 ≥95% 1072833-77-2 1mg $44 2024-03-01 Buy
Cayman Chemical 18385 MLN2238 ≥95% 1072833-77-2 5mg $193 2024-03-01 Buy
Cayman Chemical 18385 MLN2238 ≥95% 1072833-77-2 10mg $341 2024-03-01 Buy
Cayman Chemical 18385 MLN2238 ≥95% 1072833-77-2 50mg $1169 2024-03-01 Buy
TRC I942000 Ixazomib 1072833-77-2 100mg $700 2021-12-16 Buy
Product number Packaging Price Buy
18385 1mg $44 Buy
18385 5mg $193 Buy
18385 10mg $341 Buy
18385 50mg $1169 Buy
I942000 100mg $700 Buy

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Chemical Properties,Uses,Production

Uses

Ixazomib is a proteasome inhibitor that acts by preventing cell growth in solid tumours. It is an anticancer agent that is used to treat patients with multiple myeloma and is potentially neurotoxic.

Definition

ChEBI: A glycine derivative that is the amide obtained by formal condensation of the carboxy group of N-(2,5-dichlorobenzoyl)glycine with the amino group of [(1R)-1-amino-3-methylbutyl]boronic acid. The active metabolite of ixa omib citrate, it is used in combination therapy for treatment of multiple myeloma.

target

chymotrypsin-like proteolytic (β5) site of the 20S proteasome

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Suppliers

Global( 195)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai finete Pharmaceutical Co., Ltd. 		+86-18221039705 CHINA 139 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Lianyungang happen teng technology co., LTD 		15950718863 wang666xt@163.com CHINA 295 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Supplier Advantage
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai finete Pharmaceutical Co., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
Lianyungang happen teng technology co., LTD 		58
career henan chemical co 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Chongqing Chemdad Co., Ltd 		58

View Lastest Price from (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid pictures 2024-03-29 (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
1072833-77-2
 US $6.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid pictures 2021-09-29 (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
1072833-77-2
 US $0.00 / g 1g 98%-102% 100G WUHAN FORTUNA CHEMICAL CO., LTD
(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid pictures 2019-07-06 (R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid
1072833-77-2
 US $2.00 / kg 1kg 99% 100kg Career Henan Chemical Co

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid Spectrum

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid(1072833-77-2)MS

1072833-77-2((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid)Related Search:

Ixazomib citrate (USAN) Acetamide, 2-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]- Ixazomib Impurity 1 CUDC-101 Brivanib alaninate
AC480 (BMS-599626) 1H-indazole-7-carboxylic acid tert-butyl (S)-3-(4-bromophenyl)piperidine-1-carboxylate Niraparib (S)-tert-butyl 3-(4-aMinophenyl)piperidine-1-carboxylate
Piperidine, 3-(4-bromophenyl)- (aR,3aS,4S,6S,7aR)-Hexahydro-3a,8,8-trimethyl-alpha-(2-methylpropyl)-4,6-methano-1,3,2-benzodioxaborole-2-methanamine 2,2,2-trifluoroacetate 4-piperidin-3-ylaniline CHEMBRDG-BB 7959525 Methyl 3-formyl-2-nitrobenzoate
Bortezomib MLN9708 MK-2206 2HCl

1of4

(R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutylboronic acid B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid ixazomib(MLN2238) B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]boronic acid Ixazomib (MLN2238) MLN2238(iaxzomib) MLN2238(Ixazomib) MLN2238;MLN 2238;MLN-2238 IXAZOMIB;MLN 2238;MLN-2238 CS-1976 1-(2-(2,5-dichlorobenzamido)acetamido)- 3-methylbutylboronic acid Ixazomib (MLN-9708) Ixazomib, 98%, a selective, potent, and reversible proteasome inhibitor, which inhibits the chymotrypsin-like proteolytic (5) site of the 20S proteasome with an IC50 of 3.4 nM (Ki of 0.93 nM) (1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]boronic acid Boronic acid, B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]- (R)-(1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbuyl)boronic acid Ixazomib (10mM in DMSO) Ixazomib-13C2,15NQ: What is Ixazomib-13C2,15N Q: What is the CAS Number of Ixazomib-13C2,15N MLN2238 IxazoMib Ixazomib-d7 1072833-77-2 C14H19BCl2N2O4 Inhibitors Inhibitor apis