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AC480 (BMS-599626)

AC480 (BMS-599626)
AC480 (BMS-599626) structure
CAS No.
714971-09-2
Chemical Name:
AC480 (BMS-599626)
Synonyms
AC-480;CS-341;CS-1550;BMS-599616;BMS 599626 ;AC480 (BMS-599626);BMS599626 Free base;BMS599626;AC-480; BMS 599626 (AC480);(S)-Morpholin-3-ylmethyl (4-((1-(3-fluorobenzyl)-1H-indazol-5-yl)amino)-5-methylpyrrolo[2,1-f];[(3S)-Morpholin-3-yl]methyl N-[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-5-methyl-pyrr
CBNumber:
CB12464670
Molecular Formula:
C27H27FN8O3
Formula Weight:
530.561
MOL File:
714971-09-2.mol

AC480 (BMS-599626) Properties

Density 
1.48±0.1 g/cm3(Predicted)
pka
7.27±0.46(Predicted)
FDA UNII
2252724U5N
NCI Dictionary of Cancer Terms
BMS-599626

AC480 (BMS-599626) price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical B5520 BMS-599626 >98.0%(HPLC) 714971-09-2 10mg $208 2020-06-24 Buy
TCI Chemical B5520 BMS-599626 >98.0%(HPLC) 714971-09-2 50mg $721 2020-06-24 Buy

AC480 (BMS-599626) Chemical Properties,Uses,Production

Uses

BMS-599626 is a highly selective pan-HERKinase inhibitor with IC50 of 20 and 30 nM for the inhibition of HER1and HER2, respectively.

Uses

It is a highly selective and potent inhibitor of HER1 and HER2 kinases and inhibits tumor cell proliferation through modulation of receptor signaling. BMS-599626 inhibits HER1/HER2 receptor heterodimerization and provides an additional mechanism of inhibiting tumors in which receptor coexpression and heterodimerization play a major role in driving tumor growth.

AC480 (BMS-599626) Preparation Products And Raw materials

Raw materials

Preparation Products


AC480 (BMS-599626) Suppliers

Global( 76)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21836 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22625 55
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28231 58
Amadis Chemical Company Limited
0086-571-89925085
0086-571-89925065 sales@amadischem.com China 132149 58
Chembest Research Laboratories Limited 021-20908456-
021-58180499 sales@BioChemBest.com China 5956 61
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24555 81
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15425 60
Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811783
+86 (531) 55696010 QQ 1762738062 sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market) China 1856 62
BOC Sciences 16316197922
info@bocsci.com United States 9983 65
Dalian Meilun Biotech Co., Ltd. 0411-66771943-
0411-66771945 sales@meilune.com;sales@meilune.com; China 3922 58

714971-09-2(AC480 (BMS-599626))Related Search:


  • CS-1550
  • BMS-599616
  • BMS599626 Free base
  • [(3S)-Morpholin-3-yl]methyl N-[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-5-methyl-pyrr
  • (S)-Morpholin-3-ylmethyl (4-((1-(3-fluorobenzyl)-1H-indazol-5-yl)amino)-5-methylpyrrolo[2,1-f]
  • (S)-MORPHOLIN-3-YLMETHYL 4-(1-(3-FLUOROBENZYL)-1H-INDAZOL-5-YLAMINO)-5-METHYLPYRROLO[2,1-F][1,2,4]-TRIAZIN-6-YLCARBAMATE
  • CARBAMIC ACID, [4-[[1-[(3-FLUOROPHENYL)METHYL]-1H-INDAZOL-5-YL]AMINO]-5-METHYLPYRROLO[2,1-F][1,2,4]TRIAZIN-6-YL]-, (3S)-3-MORPHOLINYLMETHYL ESTER
  • BMS 599626
  • Carbamic acid, [4-[[1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]-, (3S)-3-morpholinylmethyl ester (9CI)
  • AC-480
  • N-[4-[[1-[(3-Fluorophenyl)Methyl]-1H-indazol-5-yl]aMino]-5-Methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbaMic Acid (3S)-3-MorpholinylMethyl Ester
  • (S)-Morpholin-3-ylmethyl (4-((1-(3-fluorobenzyl)-1H-indazol-5-yl)amino)-5-methylpyrrolo[2,1-f][1,
  • AC480 (BMS-599626)
  • (S)-morpholin-3-ylmethyl 4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-ylcarbamate
  • (3S)-morpholin-3-ylmethyl N-[4-({1-[(3-fluorophenyl)methyl]-1H-indazol-5-yl}amino)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate
  • [(3S)-Morpholin-3-yl]methyl N-[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-5-methyl-pyrrolo
  • CS-341
  • BMS599626;AC-480; BMS 599626 (AC480)
  • 714971-09-2
  • 8173837-23-1
  • C27H27FN8O3
  • C26H25FN8O3
  • Aromatics
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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