Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>SC-51322

SC-51322

SC-51322 Structure
SC-51322 structure
CAS No.
146032-79-3
Chemical Name:
SC-51322
Synonyms
SC-51322;8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[3-[(2-FuranylMethyl) thio]-1-oxopropyl]hydrazide;8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacidhydrazide;Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide
CBNumber:
CB7235197
Molecular Formula:
C22H20ClN3O4S
Molecular Weight:
457.93
MDL Number:
MFCD00916246
MOL File:
Mol file
Last updated:2023-06-30 15:45:59
Request For Quotation

SC-51322 Properties

Melting point 112-114°C
RTECS HQ4002000
storage temp. Store at +4°C
solubility DMSO: ≥10mg/mL
form powder
color white to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45
RIDADR  UN 2811 6.1 / PGIII
WGK Germany  3
HazardClass  6.1
NFPA 704
0
2 0

SC-51322 price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PZ0132 SC-51322 ≥98% (HPLC) 146032-79-3 5mg $40.8 2024-03-01 Buy
Sigma-Aldrich PZ0132 SC-51322 ≥98% (HPLC) 146032-79-3 25mg $404 2024-03-01 Buy
Alfa Aesar J67002 SC-51322, 98% 146032-79-3 5mg $125 2021-12-16 Buy
Cayman Chemical 10010744 SC-51322 ≥98% 146032-79-3 1mg $20 2024-03-01 Buy
Cayman Chemical 10010744 SC-51322 ≥98% 146032-79-3 5mg $85 2024-03-01 Buy
Product number Packaging Price Buy
PZ0132 5mg $40.8 Buy
PZ0132 25mg $404 Buy
J67002 5mg $125 Buy
10010744 1mg $20 Buy
10010744 5mg $85 Buy

SC-51322 Chemical Properties,Uses,Production

Description

The prostaglandin E2 (PGE2) receptor (EP1) is involved in triggering PGE2-mediated pain as well as neuronal survival and growth. SC-51322 is a selective EP1 antagonist that inhibits PGE2 signaling in a guinea pig ileum muscle strip assay with a pA2 value of 8.1 and demonstrates analgesic activity in a mouse writhing assay with an ED50 value of 0.9 mg/kg. It is pharmacologically similar to SC-51089, but does not release hydrazine, a known carcinogen to rats, as does SC-51089. SC-51322 potentiates the vasorelaxation of human pulmonary vein induced by PGE2 with an EC50 value of 7.75 μM.

Chemical Properties

Off-White Solid

Uses

A selective E-prostanoid receptor subtype 1 (EP1) receptor antagonist which shows antihypertensive effects.

storage

Store at -20°C

SC-51322 Preparation Products And Raw materials

Raw materials

Preparation Products

SC-51322 Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32344 50
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4428 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55827 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
J & K SCIENTIFIC LTD. 76
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Chemsky（shanghai）International Co.,Ltd. 50
BOC Sciences 65
Guangzhou Isun Pharmaceutical Co., Ltd 55
EMMX Biotechnology LLC 60
Shanghai EFE Biological Technology Co., Ltd. 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58

146032-79-3(SC-51322)Related Search:

13,14-DIHYDROPROSTAGLANDIN E1 PROSTAGLANDIN F1ALPHA Latanoprost Misoprostol Acid PROSTAGLANDIN D2
Sulprostone PROSTAGLANDIN B1 Fluprostenol Prostaglandin F2a PROSTAGLANDIN A1
PROSTAGLANDIN B2 SC-51089 U-75302 L-161,982 6(R)-(4-CARBOXYPHENYLTHIO)-5(S)-HYDROXY-7(E),9(E),11(Z),14(Z)-EICOSATETRAENOIC ACID
11BETA-PROSTAGL AND IN F2ALPHA LEUKOTRIENE B4 DIMETHYL AMIDE LEUKOTRIENE D4

1of4

SC-51322 8-Chloro-2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]-dibenz(Z)[b,f][1,4]oxazepine-10(11H)-carboxylicacidhydrazide 8-Chloro-dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic Acid 2-[3-[(2-FuranylMethyl) thio]-1-oxopropyl]hydrazide Dibenz[b,f][1,4]oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-[3-[(2-furanylmethyl)thio]-1-oxopropyl]hydrazide 146032-79-3 Amines Heterocycles Inhibitors Intermediates & Fine Chemicals Pfizer compounds Pharmaceuticals Sulfur & Selenium Compounds