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2-bromo-4-methylpropiophenone

CAS No.
1451-82-7
Chemical Name:
2-bromo-4-methylpropiophenone
Synonyms
2-bromo-1-(4-methylphenyl)propan-1-one;new bmk;4-Methylphenyl 1-BroMoethyl Ketone;2-Bromo-1-(4-methylphenyl)-1-propanone;EG-2201power;2-bromo-4 '- met;good price EG-2201;2-Bromo-1-(p-tolyl);2bromo high quality;2-BROMO-4'-METHYLPROPIOPHENE
CBNumber:
CB7946938
Molecular Formula:
C10H11BrO
Molecular Weight:
227.1
MDL Number:
MFCD11131402
MOL File:
1451-82-7.mol
Last updated:2023-10-17 11:37:00

2-bromo-4-methylpropiophenone Properties

Melting point 75-77℃
Boiling point 273℃
Density 1.357
Flash point 59℃
storage temp. Refrigerator
solubility Soluble in chloroform and methanol.
form Solid
color White to Off-White
InChIKey OZLUPIIIHOOPNQ-UHFFFAOYSA-N
FDA UNII V3ZPM7TKH9

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H315-H319
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
Hazard Codes  Xn
Risk Statements  22
HS Code  2914.79.4000
NFPA 704
1
2 0

2-bromo-4-methylpropiophenone Chemical Properties,Uses,Production

Description

It is usually used as the intermediate and raw material in the fine chemistry industry. Specifically, this chemical can act as the intermediate in the synthesis of 4-methyl methcathinone HCl, which is used as the sample for development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials.1 Moreover, this compound may function as an effective ingredient to prepare the therapeutically useful 1-phenyl-2-piperidinoalkanol derivatives.2 In addition, this substance has been demonstrated to be involved in the preparation of a pharmaceutical composition comprising a pyrrole derivative, which shows a desirable activity for the treatment pollakiuria or urinary incontinence.3

Uses

2-Bromo-4'-methylpropiophenone (cas# 1451-82-7) is a compound useful in organic synthesis.

Reference

  1. Philp, M.; Shimmon, R.; Stojanovska, N.; Tahtouh, M.; Fu, S. L., Development and validation of a presumptive colour spot test method for the detection of piperazine analogues in seized illicit materials. Anal. Methods 2013, 5, 5402-5410.
  2. Alexander Wick; Jonathan Frost; Bernard Gaudilliere; Jean Bertin; Regis Dupont; Rousseau, J., Therapeutically useful 1-phenyl-2-piperidinoalkanol derivatives. US Patent 4690931 1987.
  3. Masami Tsuda; Mitsushi Tanaka; Nakamura, A., Pyrrole derivatives and medicinal composition. US Patent 5998459 1999.

Chemical Properties

Off-White Solid

Uses

It employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field. Also used as intermediate for 4-methylmethcathinone.

2-bromo-4-methylpropiophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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