ChemicalBook
Chinese Japanese Germany

Nonivamide

Description References
Nonivamide
Nonivamide
CAS No.
2444-46-4
Chemical Name:
Nonivamide
Synonyms
PAVA;NonvaMide;NON-4-ENE;AH-23491X;NONIVAMIDE;NSC 172795;capscaisin;Capsaicinoid;Capsaicin std.;NONYLVANYLAMIDE
CBNumber:
CB8103743
Molecular Formula:
C17H27NO3
Formula Weight:
293.4
MOL File:
2444-46-4.mol

Nonivamide Properties

Melting point:
54°C
Density 
1,1 g/cm3
FEMA 
2787 | NONANOYL 4-HYDROXY-3-METHOXYBENZYLAMIDE
Flash point:
190°C
storage temp. 
2-8°C
solubility 
methanol: 100 mg/mL, clear to slightly hazy
form 
powder
color 
white to off-white
BRN 
2144300
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
2444-46-4(CAS DataBase Reference)
EPA Substance Registry System
Nonanamide, N-[(4-hydroxy-3-methoxyphenyl) methyl]-(2444-46-4)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T,Xi
Risk Statements  25-36/37/38-43
Safety Statements  26-45-37/39-36/37
RIDADR  UN 3462 6.1/PG 2
WGK Germany  3
RTECS  RA5998000
19
HazardClass  6.1
PackingGroup  II
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

Nonivamide price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich V9130 N-Vanillylnonanamide ≥97%, powder 2444-46-4 1g $53 2018-11-20 Buy
Sigma-Aldrich S567868 N-VANILLYLNONANOAMIDE AldrichCPR 2444-46-4 50mg $133 2018-11-13 Buy
TCI Chemical M0900 N-Vanillylnonanamide [=Capsaicin (Synthetic)] >98.0%(HPLC)(N) 2444-46-4 10g $132 2018-11-22 Buy
Cayman Chemical 25328 Nonivamide ≥98% 2444-46-4 1g $28 2018-11-19 Buy
Cayman Chemical 25328 Nonivamide ≥98% 2444-46-4 5g $98 2018-11-19 Buy

Nonivamide Chemical Properties,Uses,Production

Description

Nonivamide is also called pelargonic acid vanillylamide or PAVA. It is a capsaicinoid. Nonivamide, isolated from peppers, is a naturally occurring analog of capsaicin (sc-3577). Similar to capsaicin, nonivamide can activate the TRPV1 receptor, thus, stimulate the firing rate of dopaminergic neurons in the ventral tegmental area of the brain and to increase the expression of the serotonin receptor gene HTR2A. Nonivamide is with lower TRPV1 binding affinity, thus, a reduced pungency (9 200 000 scoville heat units) compared to capsaicin (16 000 000 scoville heat units).
Nonivamide is used in the food production to add a hot sensation to flavoring agents and spice mixtures. It is also used in the sweets and confectionary industries to add hot sensation into products. In pharmaceutical industries, nonivamide is used as a cheaper alternative for capsaicin. Warming or heating ointment of nonivamide is used for temporary relief of pain from conditions such as rheumatism, arthritis, lumbao, muscular aches, sprains and strains, sporting injuries and other conditions where local warmth is beneficial. Finalgon is one of the common product utilizing nonivamide for this purpose. Nonivamide is also used as an incapacitant spray, affecting the assailed person’s eyes, causing intense pain and swelling.

References

[1] https://www.scbt.com/scbt/product/nonivamide-2444-46-4
[2] https://pubchem.ncbi.nlm.nih.gov/compound/N-Vanillylnonanamide#section=Clinical-Trials
[3] https://cot.food.gov.uk/sites/default/files/cot/cotsection.pdf

Chemical Properties

solid

Uses

analgesic (topical), depletes Substance P

Uses

N-Vanillylnonanamide is a synthetic analogue of Capsaicin (175680) with similar bioactivity.

Definition

ChEBI: A capsaicinoid that is the carboxamide resulting from the formal condensation of the amino group of 4-hydroxy-3-methoxybenzylamine with the carboxy group of nonanoic acid. It is the active ingredient in many pepper sprays.

Nonivamide Preparation Products And Raw materials

Raw materials

Preparation Products


Nonivamide Suppliers

Global( 290)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19958 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22058 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20795 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32764 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 893 55
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2200 58
Qingdao Hongjin Trading Co., Ltd.
0532-83657313
hjt@hong-jin.com CHINA 113 58
Shanghai Arbor Chemical Co., Ltd.
021-60451682
021-60451683 act@arborchemical.com CHINA 905 58
Kono Chem Co., Ltd
+86-132 8924 6953
info@konochemical.com CHINA 2164 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3624 58

View Lastest Price from Nonivamide manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-26 Nonivamide
2444-46-4
US $300.00 / KG 10G 99% customise career henan chemical co

2444-46-4(Nonivamide)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved