3-Nitrophthalic anhydride
- CAS No.
- 641-70-3
- Chemical Name:
- 3-Nitrophthalic anhydride
- Synonyms
- 1,3-Isobenzofurandione, 4-nitro-;3-Nitrophthalic Acid Anhydride;4-NITRO-ISOBENZOFURAN-1,3-DIONE;NSC 4134;NSC 27006;3-NitrophthaL;Pomalidomide INT;Apremilast Impurity 90;Pomalidomide Impurity 36;3-NITROPHTHALIC ANHYDRIDE
- CBNumber:
- CB8116378
- Molecular Formula:
- C8H3NO5
- Molecular Weight:
- 193.11
- MDL Number:
- MFCD00005921
- MOL File:
- 641-70-3.mol
- MSDS File:
- SDS
Melting point | 163-165 °C (lit.) |
---|---|
Boiling point | 329.3°C (rough estimate) |
Density | 1.6392 (rough estimate) |
refractive index | 1.4700 (estimate) |
storage temp. | Store below +30°C. |
form | Crystalline Powder |
color | Beige to yellow |
Water Solubility | MAY DECOMPOSE |
Sensitive | Moisture Sensitive |
BRN | 179963 |
CAS DataBase Reference | 641-70-3(CAS DataBase Reference) |
FDA UNII | X2BXS9KCY2 |
NIST Chemistry Reference | 3-Nitrophthalic anhydride(641-70-3) |
EPA Substance Registry System | 1,3-Isobenzofurandione, 4-nitro- (641-70-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-21 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29173980 | |||||||||
NFPA 704 |
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3-Nitrophthalic anhydride price More Price(44)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.20903 | 3-Nitrophthalic anhydride for synthesis | 641-70-3 | 25g | $87.5 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.20903 | 3-Nitrophthalic anhydride for synthesis | 641-70-3 | 100g | $164 | 2024-03-01 | Buy |
Sigma-Aldrich | 156884 | 3-Nitrophthalic anhydride 98% | 641-70-3 | 5g | $76.2 | 2024-03-01 | Buy |
Sigma-Aldrich | 156884 | 3-Nitrophthalic anhydride 98% | 641-70-3 | 25g | $148.8 | 2024-03-01 | Buy |
TCI Chemical | N0245 | 3-Nitrophthalic Anhydride >97.0%(GC)(T) | 641-70-3 | 25g | $33 | 2024-03-01 | Buy |
3-Nitrophthalic anhydride Chemical Properties,Uses,Production
Chemical Properties
Beige to yellow crystalline powder
Uses
An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). Reactions with aminoquinazolinones yield phthalimidoquinazolinones.
Uses
4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.
Preparation
3-Nitrophthalic anhydride can be prepared by heating 3-nitrophthalic acid under various conditions and by the action of acetic anhydride, essentially as in the procedure described. The direct nitration of phthalic anhydride yields 3-nitrophthalic anhydride together with the isomeric 4-nitro compound.
Purification Methods
Crystallise it from *C6H6, *C6H6/pet ether, Me2CO, AcOH, or Ac2O (m 164-165o). Dry it at 100o. [Beilstein 17 III/IV 6149, 17/11 V 266.]
3-Nitrophthalic anhydride Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Asia Chem I and E (Jiangsu) Co Ltd | +8615105181882 | mera.z@nitrobenzenechemical.com | China | 129 | 58 |
Hebei Kangcang new material Technology Co., LTD | +8619133911216 | fanfan@kangcang.com.cn | China | 340 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
View Lastest Price from 3-Nitrophthalic anhydride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-04-28 | 3-Nitrophthalic anhydride
641-70-3
|
US $9.00-80.00 / g | 10g | min99% | 10 tons | Hebei Kangcang new material Technology Co., LTD | ||
2024-04-28 | 3-Nitrophthalic anhydride
641-70-3
|
US $62.79 / Kg/Drum | 25Kg/Drum | 98.00%HPLC | 8.8tons/month | Asia Chem I and E (Jiangsu) Co Ltd | ||
2023-03-06 | 3-Nitrophthalic anhydride
641-70-3
|
US $10.70 / Kg/Bag | 10g | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD |
- 3-Nitrophthalic anhydride
641-70-3
- US $9.00-80.00 / g
- min99%
- Hebei Kangcang new material Technology Co., LTD
- 3-Nitrophthalic anhydride
641-70-3
- US $62.79 / Kg/Drum
- 98.00%HPLC
- Asia Chem I and E (Jiangsu) Co Ltd
- 3-Nitrophthalic anhydride
641-70-3
- US $10.70 / Kg/Bag
- 99%
- Hebei Guanlang Biotechnology Co,.LTD