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Methyl propionate

Description References
Methyl propionate
Methyl propionate structure
Chemical Name:
Methyl propionate
Molecular Formula:
Formula Weight:
MOL File:

Methyl propionate Properties

Melting point:
-88 °C
Boiling point:
79 °C(lit.)
0.915 g/mL at 25 °C(lit.)
vapor density 
3 (vs air)
vapor pressure 
40 mm Hg ( 11 °C)
refractive index 
n20/D 1.376(lit.)
Flash point:
43 °F
storage temp. 
Flammables area
H2O: soluble16 parts
Clear colorless
explosive limit
Water Solubility 
5 g/100 mL at 20 ºC
JECFA Number
Stable. Highly flammable. Incompatible with strong oxidizing agents, acids, bases. Readily forms explosive mixtures with air. Moisture sensitive.
CAS DataBase Reference
554-12-1(CAS DataBase Reference)
NIST Chemistry Reference
Propanoic acid, methyl ester(554-12-1)
EPA Substance Registry System
Propanoic acid, methyl ester(554-12-1)
  • Risk and Safety Statements
Signal word  Danger
Hazard statements  H225-H332
Precautionary statements  P210-P261-P370+P378-P403+P235-P280a-P303+P361+P353-P304+P340-P501a
Hazard Codes  F,Xn
Risk Statements  11-20-2017/11/20
Safety Statements  16-24-29-33
RIDADR  UN 1248 3/PG 2
WGK Germany  1
RTECS  UF5970000
Autoignition Temperature 876 °F
HSCode  2915 50 00
HazardClass  3
PackingGroup  II
Toxicity LD50 orally in Rabbit: 5000 mg/kg

NFPA 704

Diamond Hazard Value Description
1 0
Health   1 Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride)
Flammability   3 Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone)
Instability   0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)

(NFPA, 2010)

Methyl propionate price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 109258 Methyl propionate 99% 554-12-1 100ml $26.6 2018-11-13 Buy
Sigma-Aldrich 109258 Methyl propionate 99% 554-12-1 500ml $71 2018-11-13 Buy
TCI Chemical P0508 Methyl Propionate >99.0%(GC) 554-12-1 25mL $19 2018-11-22 Buy
TCI Chemical P0508 Methyl Propionate >99.0%(GC) 554-12-1 500mL $66 2018-11-22 Buy
Alfa Aesar A14944 Methyl propionate, 99% 554-12-1 500ml $69.5 2018-11-13 Buy

Methyl propionate Chemical Properties,Uses,Production


Methyl propionate is an organic compound belonging to the family of carboxylic acid esters, which is commonly applied as a solvent for cellulose nitrate and lacquers. It also serves as a raw material in organic synthesis for manufacturing paints, varnishes and other chemical productions such as methyl methacrylate. Besides, the fruity smell and taste of methyl propanoate results in its usage of fragrances and flavoring agents.
Methyl propanoate can be synthesized by esterifying propionic acid with methanol. In the field of industry, it is produced by the reaction of ethylene with carbon monoxide and methanol in the presence of nickel carbonyl.



Methyl propionate, also known as methyl propanoate, is a chemical compound with the molecular formula C4H8O2. It is a volatile ester with a sweet, fruity, rum-like odor.

Chemical Properties

colourless liquid

Chemical Properties

Methyl propionate is colorless liquid with a sweet, fruity, rum-like odor.

Chemical Properties

Methyl propionate has a fruity odor reminiscent of rum with a sweet flavor suggestive of black currant. May be prepared by direct esterification of the acid with methanol in the presence of concentrated H2S04.

Chemical Properties

Methyl propionate has a fruity odor reminiscent of rum. It has a sweet flavor suggestive of black currant


Reported found in guava, honey, melon, pineapple, raspberry, blackberry, strawberry, cheddar cheese, cooked beef, coffee, soy protein, durian (Durio zibethinus), starfruit, plum brandy, cherimoya, kiwifruit, naranjilla, mussels and rooibus tea (Aspalathus linearis)


Methyl propionate is used as a solvent for cellulose nitrate and lacquers, and as a raw material for the production of paints, varnishes and other chemicals such as methyl methacrylate.
Due to its fruity smell and taste, it is also used in fragrances and flavoring.


In organic synthesis.


Methyl propionate can be prepared by esterification of propionic acid with methanol. Industrially, it is prepared by the reaction of ethylene with carbon monoxide and methanol in the presence of nickel carbonyl.

Aroma threshold values

Detection: 100 ppb to 8.8 ppm

General Description

A clear colorless liquid. Flash point 28°F. Density about the same as water. Vapors heavier than air. May irritate skin, eyes, and mucous membranes. Used for flavoring and as a solvent.

Air & Water Reactions

Highly flammable. Soluble in water.

Reactivity Profile

Methyl propionate reacts with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction with caustic solutions. Flammable hydrogen is generated with alkali metals and hydrides.


Flammable, dangerous fire risk, explosivelimits in air 2.5–13%.

Health Hazard

May cause toxic effects if inhaled or absorbed through skin. Inhalation or contact with material may irritate or burn skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Moderately toxic by ingestion. Mildly toxic by inhalation. A skin irritant. A very dangerous fire hazard when exposed to heat, flame, or oxidizers. Explosive in the form of vapor when exposed to heat or flame. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and irritating fumes.

Chemical Synthesis

By direct esterification of the acid with methanol in the presence of concentrated H2SO4

Potential Exposure

Used as a solvent; and in making paints, lacquers, and varnishes. Also used in flavorings and fragrances


UN1248 Methyl propionate, Hazard Class: 3; Labels: 3-Flammable liquid.

Purification Methods

Wash the ester with saturated aqueous NaCl, then dry it with Na2CO3 and distil it from P2O5. (This removes any free acid and alcohol.) It has also been dried with anhydrous CuSO4. [Beilstein 2 IV 104.]


May form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Keep away from heat and moisture.

Methyl propionate Preparation Products And Raw materials

Raw materials

Preparation Products

Methyl propionate Suppliers

Global( 173)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733 CHINA 32447 55
career henan chemical co
+86-371-86658258 CHINA 30002 58
Chemwill Asia Co.,Ltd.
86-21-51861608;;; CHINA 23980 58
Hubei Jusheng Technology Co.,Ltd.
027-59599243 CHINA 28236 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114 CHINA 6372 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23049 58
Chongqing Chemdad Co., Ltd
+86-13650506873 CHINA 35440 58
Liyang Ruipu New Materials Co., Ltd. 0519-82038123 18951201333
0519-87015112 China 9950 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
86-10-82849933; China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40269 62

View Lastest Price from Methyl propionate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-21 Methyl propionate
US $1.00 / kg 1g 99% 100KG career henan chemical co

Methyl propionate Spectrum

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