EC 5.3.4.1
- CAS No.
- 37318-49-3
- Chemical Name:
- EC 5.3.4.1
- Synonyms
- PDI;DSBA;PADI1;PDA2;HPAD10;EC 5.3.4.1;LA16c-314G4.2;PAD1, GST tagged human;PROTEIN DISULFIDE ISOMERASE;Native Human Topoisomerase II α
- CBNumber:
- CB8363754
- Molecular Formula:
- C7H5Cl2NO5S
- Molecular Weight:
- 0
- MDL Number:
- MFCD00163364
- MOL File:
- Mol file
- MSDS File:
- SDS
storage temp. | -20°C |
---|---|
form | lyophilized powder |
FDA UNII | 5WLU24LOMH |
SAFETY
Risk and Safety Statements
WGK Germany | 3 |
---|---|
F | 3-10-21 |
HS Code | 3504009000 |
EC 5.3.4.1 price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | P3818 | Protein Disulfide Isomerase from bovine liver >95% (SDS-PAGE), ≥100?units/mg protein, lyophilized powder | 37318-49-3 | 0.1mg | $175 | 2024-03-01 | Buy |
Sigma-Aldrich | P3818 | Protein Disulfide Isomerase from bovine liver >95% (SDS-PAGE), ≥100?units/mg protein, lyophilized powder | 37318-49-3 | 250μg | $208.2 | 2024-03-01 | Buy |
Sigma-Aldrich | SAB2501845 | Anti-PDIA2 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 37318-49-3 | 100μG | $545 | 2023-01-07 | Buy |
Sigma-Aldrich | SAB2501851 | Anti-PDIA2 antibody produced in goat affinity isolated antibody, buffered aqueous solution | 37318-49-3 | 100μG | $505 | 2022-05-15 | Buy |
Usbiological | 156500 | Protein Disulfide Isomerase | 37318-49-3 | 10ug | $345 | 2021-12-16 | Buy |
EC 5.3.4.1 Chemical Properties,Uses,Production
Uses
Protein Disulfide Isomerase from bovine liver has been used:
- to study the functional role of PDI in parasite infection and the interaction between macrophage PDI and?L. chagasi
- in the in vitro translation reaction for the generation of disulfide bonds
- in insulin-disulfide reduction assay and peptide binding assay
- as a positive control in thiol-disulfide oxidoreductase activity assay
General Description
Protein disulfide isomerase (PDI) from bovine liver is a homodimer with a molecular weight of 107 kDa with the monomer corresponding to 57 kDa. The isoelectric point (pI) is approximately 4.2. The enzyme is a glycoprotein with 12% total carbohydrate content comprising of mannose, galactose, N-acetyl neuraminic acid (NANA) and 2-acetamido-2-deoxyglucose. PDI is an ubiquitous redox chaperone enzyme. It belongs to the, thioredoxin superfamily and is high conserved.
Biochem/physiol Actions
Protein Disulfide Isomerase (PDI) is mainly located in the endoplasmic reticulum (ER), where it assists in protein-folding and thiol-disulfide exchanges. It aids protein refolding in vitro allowing recombinant proteins to achieve their native state.
EC 5.3.4.1 Preparation Products And Raw materials
Raw materials
Preparation Products
EC 5.3.4.1 Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Nanjing Peptide Biotech Ltd. | 025-025-58361106-805-805 13082558573 | liugang@njpeptide.com | China | 9978 | 55 |
Guangzhou Tomums Life Science Co., Ltd. | 020-31155029 18902330969 | sales@tomums.cn | China | 4698 | 58 |
Henan Weituxi Chemical Technology Co., Ltd. | 0371-63284658 18135795563 | 2885349392@qq.com | China | 10026 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
Shanghai Yaji Biological Technology Co., Ltd. | 021-34661275 15301693058 | yajikit@163.com | China | 9592 | 58 |
JiangSu Star Science Co.,Ltd | 400-605-7200 17312445705 | sales022@b2star.com | China | 3764 | 58 |
Shanghai Yingxin laboratory equipment Co., Ltd | 021-021-59178156 15300768757 | 359382369@qq.com | China | 10678 | 58 |
Shanghai Guchen Biotechnology Co., LTD | 021-34675735 19147740836 | 1986399151@qq.com | China | 9849 | 58 |
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