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Tetramethylol acetylenediurea

CAS No.
5395-50-6
Chemical Name:
Tetramethylol acetylenediurea
Synonyms
Tetramethylol acetyl;Tetrahydroxy glycoluril;Tetramethylol glycoluril;Tetramethylol acetylenedurea;Tetramethylol acetylenediurea;Tetramethylol acetylene diuriene;Tetramethylol acetylenediurea TMAD;Tetrakis (hydroxy methy1) glycoluril;1,3,4,6-tetramethylol-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-quinone;Factory supply Tetramethylol Acetylenediurea CAS 5395-50-6 high quality
CBNumber:
CB8855149
Molecular Formula:
C8H14N4O6
Molecular Weight:
262.22
MDL Number:
MFCD00043995
MOL File:
5395-50-6.mol
MSDS File:
SDS
Last updated:2025-12-31 14:38:37
Product description Number Pack Size Price
1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione min. 95.0 % T3297 25G $33
1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione min. 95.0 % T3297 100G $91
TetramethylolAcetylenediurea T889708 5g $55
Tetramethylolacetylenediurea O477 500g $267
TETRAMETHYLOL ACETYLENEDIUREA 95.00% LIN0000332 5G $909.56
More product size

Tetramethylol acetylenediurea Properties

Melting point 137-138 °C
Boiling point 624.2±55.0 °C(Predicted)
Density 1.697±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly, Sonicated)
form Solid
pka 13.90±0.10(Predicted)
color White to Off-White
Cosmetics Ingredients Functions ANTIMICROBIAL
InChI InChI=1S/C8H14N4O6/c13-1-9-5-6(11(3-15)7(9)17)12(4-16)8(18)10(5)2-14/h5-6,13-16H,1-4H2
InChIKey UUGLSEIATNSHRI-UHFFFAOYSA-N
SMILES C(N1C(N(C2N(C(N(C21)CO)=O)CO)CO)=O)O
FDA UNII 3BH30G5P9H
EPA Substance Registry System Imidazo[4,5-d]imidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)- (5395-50-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
TSCA  TSCA listed

Tetramethylol acetylenediurea price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T3297 1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione min. 95.0 % 5395-50-6 25G $33 2026-04-30 Buy
TCI Chemical T3297 1,3,4,6-Tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione min. 95.0 % 5395-50-6 100G $91 2026-04-30 Buy
TRC T889708 TetramethylolAcetylenediurea 5395-50-6 5g $55 2021-12-16 Buy
AK Scientific O477 Tetramethylolacetylenediurea 5395-50-6 500g $267 2021-12-16 Buy
American Custom Chemicals Corporation LIN0000332 TETRAMETHYLOL ACETYLENEDIUREA 95.00% 5395-50-6 5G $909.56 2021-12-16 Buy
Product number Packaging Price Buy
T3297 25G $33 Buy
T3297 100G $91 Buy
T889708 5g $55 Buy
O477 500g $267 Buy
LIN0000332 5G $909.56 Buy

Tetramethylol acetylenediurea Chemical Properties,Uses,Production

Uses

Tetramethylol acetylene diurea is a formaldehyde type of textile-finish resin.

Uses

Crosslinker, Fungicide, Concrete additive

Uses

Tetramethylol Acetylenediurea is a useful additive for forming etching patterns in semiconductor manufacturing.

Flammability and Explosibility

Not classified

Synthesis

Formaldehyde

50-00-0

Glycoluril

496-46-8

Tetramethylol acetylenediurea

5395-50-6

In a suitable reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser, 688 parts (10 mol) of a 44% aqueous formaldehyde solution were added and the pH was adjusted to 8.7 with 22 parts of 0.5 N NaOH solution.The temperature of the reaction system was maintained at 40 °C to which 284 parts (2 mol) of glyburide were subsequently added. During the reaction, the temperature was gradually increased to 55 °C, at which time most of the glyburide was dissolved. After about 15 minutes, the pH of the reaction system was adjusted to 8.0 with 5 parts of 0.5N NaOH solution to obtain a clarified light yellow solution. This solution was subjected to reduced pressure distillation at 50°C to remove the water until about 640 parts remained in the reaction vessel. The concentrated syrupy product was poured into 800 parts of methanol and a white crystalline precipitate was precipitated. After filtration and drying, 483 parts (92% yield) of 1,3,4,6-tetrakis(hydroxymethyl)tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione were obtained with a melting point of 132°C~136°C.

References

[1] Patent: WO2014/166347, 2014, A1. Location in patent: Page/Page column 14
[2] Patent: WO2015/143974, 2015, A1. Location in patent: Page/Page column 15; 16
[3] Chemistry of Heterocyclic Compounds, 2006, vol. 42, # 3, p. 365 - 376
[4] Russian Journal of Applied Chemistry, 2016, vol. 89, # 1, p. 132 - 139
[5] Zh. Prikl. Khim. (S.-Peterburg, Russ. Fed.), 2016, vol. 89, # 1, p. 103 - 111,9

Tetramethylol acetylenediurea Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 164)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Pesan Chemical Co.,Ltd.
+8615921661320 zhangk@pesanchem.com China 1000 58
Hebei Yanxi Chemical Co., Ltd.
+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365 mina@chuanghaibio.com China 18126 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21590 55
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5906 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29794 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 9545 58
Hebei Runbin Biotechnology Co. LTD
13180553332 2179877681@qq.com CHINA 990 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58

View Lastest Price from Tetramethylol acetylenediurea manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,3,4,6-tetrakis(hydroxymethyl)-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione pictures 2025-12-24 1,3,4,6-tetrakis(hydroxymethyl)-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione
5395-50-6
US $0.00-0.00 / KG 1KG 0.99 1 tons Changzhou Pesan Chemical Co.,Ltd.
Tetramethylol acetylenediurea pictures 2025-12-01 Tetramethylol acetylenediurea
5395-50-6
US $0.00-0.00 / KG 1KG 98 10000KGS Shaanxi Dideu New Materials Co. Ltd
Tetramethylol acetylenediurea pictures 2025-06-27 Tetramethylol acetylenediurea
5395-50-6
US $30.00-10.00 / KG 50KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd

Tetramethylol acetylenediurea Spectrum

Tetramethylol acetylenediurea 1,3,4,6-Tetrakis-hydroxymethyl-tetrahydro-imidazo(4,5-d)imidazole-2,5-dione tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1H,3H)-dione Imidazo4,5-dimidazole-2,5(1H,3H)-dione, tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)- Tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazol-2,5(1H,3H)-dion Tetramethylol acetylene diuriene Tetrakis (hydroxy methy1) glycoluril 1,3,4,6-Tetrakis(hydroxymethyl)-3a,4,6,6a-tetrahydroimidazo[4,5-d]imidazole-2,5(1H,3H)-dione 1,3,4,6-Tetrakis(hydroxymethyl)octahydroimidazo[4,5-d]imidazole-2,5-dione 3a,4,6,6a-Tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1H,3H)-dione 1,3,4,6-tetrakis(hydroxymethyl)-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-dione 1,3,4,6-tetramethylol-3a,6a-dihydroimidazo[4,5-d]imidazole-2,5-quinone Tetramethylol acetyl 1,3,4,6-Tetrakis(hydroxyMethyl)tetrahydroiMidazo[4,5-d]iMidazole-2,5(1H,3H)-dione 1,3,4,6-Tetrakis-hydroxymethyl-tetrahydro-imidazo[4,5-d]imidazole-2,5-dionr in aqueous solution Tetramethylol acetylenedurea Tetrahydroxy glycoluril Tetramethylol glycoluril Factory supply Tetramethylol Acetylenediurea CAS 5395-50-6 high quality Tetramethylol acetylenediurea TMAD Tetrahydro-1,3,4,6-tetrakis(hydroxymethyl)imidazo[4,5-d]imidazole-2,5(1H,3H)-dione (TMAD) 5395-50-6 C8H14N4O6