ChemicalBook >> CAS DataBase List >>atrasentan
atrasentan
- CAS No.
- 173937-91-2
- Chemical Name:
- atrasentan
- Synonyms
- A-147627;atrasentan;(+)-A 127722;(+)-A 127722;Atrasentan (ABT-627);A127722, CID 5310990;(+)-A 127722; ABT-627; A 127722; ABT 627;Atrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627;(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid;(2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID
- CBNumber:
- CB91320566
- Molecular Formula:
- C29H38N2O6
- Molecular Weight:
- 510.62
- MDL Number:
- MFCD00940177
- MOL File:
- 173937-91-2.mol
- MSDS File:
- SDS
Last updated:2023-09-04 16:42:00
Melting point | 122-124° |
---|---|
Boiling point | 659.4±55.0 °C(Predicted) |
Density | 1.188±0.06 g/cm3(Predicted) |
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 3.49±0.60(Predicted) |
color | Off-White |
NCI Dictionary of Cancer Terms | atrasentan |
FDA UNII | V6D7VK2215 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
atrasentan price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | A793925 | Atrasentan | 173937-91-2 | 25mg | $745 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0005136 | ATRASENTAN 95.00% | 173937-91-2 | 5MG | $550 | 2021-12-16 | Buy |
CSNpharm | CSN18015 | Atrasentan | 173937-91-2 | 50mg | $784 | 2021-12-16 | Buy |
CSNpharm | CSN18015 | Atrasentan | 173937-91-2 | 5mg | $242 | 2021-12-16 | Buy |
Crysdot | CD31002983 | Atrasentan 98+% | 173937-91-2 | 5mg | $250 | 2021-12-16 | Buy |
atrasentan Chemical Properties,Uses,Production
Uses
Palliative treatment of bone pain due to metastatic prostate cancer and disease progression (endothelin (ETA) receptor antagonist).
Uses
Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.
Definition
ChEBI: Atrasentan is a member of pyrrolidines.
atrasentan Preparation Products And Raw materials
Raw materials
Preparation Products
atrasentan Suppliers
Global( 64)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
GL Biochem (Shanghai) Ltd. | +86-021-61263370 +86-18901917034 | CHINA | 3904 | 58 | |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com | China | 20000 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
Xi'an ZB Biotech Co.,Ltd | sales03@xazbbio.com | CHINA | 722 | 58 | |
Suzhou Haiben Pharmaceutical Co., Ltd | 14760821013; 14760821013 | 1816280386@qq.com | China | 9036 | 58 |
View Lastest Price from atrasentan manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-01-10 | atrasentan
173937-91-2
|
US $0.01 / KG | 1KG | 98%; 99% | 500g;1kg; 25kg | Career Henan Chemical Co |
- atrasentan
173937-91-2
- US $0.01 / KG
- 98%; 99%
- Career Henan Chemical Co
173937-91-2(atrasentan)Related Search:
atrasentan
(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid
(+)-A 127722
A-147627
(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid
(2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID
A127722, CID 5310990
Atrasentan (ABT-627)
(+)-A 127722; ABT-627; A 127722; ABT 627
Atrasentan [2R,3R,4S]-2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-[[(N,N-dibutylamino)-carboxyl]methyl]pyrrolidine-3-carboxylic acid
3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-, (2R,3R,4S)-
(2R,3R,4S)-4-(Benzod1,3dioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid.HCl
(+)-A 127722
Atrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627
173937-91-2
API