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atrasentan

CAS No.
173937-91-2
Chemical Name:
atrasentan
Synonyms
A-147627;atrasentan;(+)-A 127722;(+)-A 127722;Atrasentan (ABT-627);A127722, CID 5310990;(+)-A 127722; ABT-627; A 127722; ABT 627;Atrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627;(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid;(2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID
CBNumber:
CB91320566
Molecular Formula:
C29H38N2O6
Molecular Weight:
510.62
MDL Number:
MFCD00940177
MOL File:
173937-91-2.mol
MSDS File:
SDS
Last updated:2023-09-04 16:42:00

atrasentan Properties

Melting point 122-124°
Boiling point 659.4±55.0 °C(Predicted)
Density 1.188±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.49±0.60(Predicted)
color Off-White
NCI Dictionary of Cancer Terms atrasentan
FDA UNII V6D7VK2215

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

atrasentan price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A793925 Atrasentan 173937-91-2 25mg $745 2021-12-16 Buy
American Custom Chemicals Corporation API0005136 ATRASENTAN 95.00% 173937-91-2 5MG $550 2021-12-16 Buy
CSNpharm CSN18015 Atrasentan 173937-91-2 50mg $784 2021-12-16 Buy
CSNpharm CSN18015 Atrasentan 173937-91-2 5mg $242 2021-12-16 Buy
Crysdot CD31002983 Atrasentan 98+% 173937-91-2 5mg $250 2021-12-16 Buy
Product number Packaging Price Buy
A793925 25mg $745 Buy
API0005136 5MG $550 Buy
CSN18015 50mg $784 Buy
CSN18015 5mg $242 Buy
CD31002983 5mg $250 Buy

atrasentan Chemical Properties,Uses,Production

Uses

Palliative treatment of bone pain due to metastatic prostate cancer and disease progression (endothelin (ETA) receptor antagonist).

Uses

Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.

Definition

ChEBI: Atrasentan is a member of pyrrolidines.

atrasentan Preparation Products And Raw materials

Raw materials

Preparation Products

atrasentan Suppliers

Global( 64)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
GL Biochem (Shanghai) Ltd.
+86-021-61263370 +86-18901917034 CHINA 3904 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
ZHEJIANG JIUZHOU CHEM CO., LTD
+86-0576225566889 +86-13454675544 admin@jiuzhou-chem.com;jamie@jiuzhou-chem.com;alice@jiuzhou-chem.com China 20000 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8474 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131981 58
Xi'an ZB Biotech Co.,Ltd sales03@xazbbio.com CHINA 722 58
Suzhou Haiben Pharmaceutical Co., Ltd 14760821013; 14760821013 1816280386@qq.com China 9036 58

View Lastest Price from atrasentan manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
atrasentan pictures 2020-01-10 atrasentan
173937-91-2
US $0.01 / KG 1KG 98%; 99% 500g;1kg; 25kg Career Henan Chemical Co
  • atrasentan pictures
  • atrasentan
    173937-91-2
  • US $0.01 / KG
  • 98%; 99%
  • Career Henan Chemical Co

atrasentan Spectrum

atrasentan (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid (+)-A 127722 A-147627 (2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid (2S,3S,4R)-4-(1,3-BENZODIOXOL-5-YL)-1-[2-(DIBUTYLAMINO)-2-OXOETHYL]-2-(4-METHOXYPHENYL)PYRROLIDINE-3-CARBOXYLIC ACID A127722, CID 5310990 Atrasentan (ABT-627) (+)-A 127722; ABT-627; A 127722; ABT 627 Atrasentan [2R,3R,4S]-2-(4-methoxyphenyl)-4-(1,3-benzodioxol-5-yl)-1-[[(N,N-dibutylamino)-carboxyl]methyl]pyrrolidine-3-carboxylic acid 3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-, (2R,3R,4S)- (2R,3R,4S)-4-(Benzod1,3dioxol-5-yl)-1-(2-(dibutylamino)-2-oxoethyl)-2-(4-methoxyphenyl)pyrrolidine-3-carboxylic acid.HCl (+)-A 127722 Atrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627 173937-91-2 API